| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
melatonin
[no description available] | 2.03 | 1 | 0 | acetamides;
tryptamines | anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger |
chloroquine
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.. chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis. | 2.1 | 1 | 0 | aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound | anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug |
phenindione
Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234) | 2.15 | 1 | 0 | aromatic ketone;
beta-diketone | anticoagulant |
streptonigrin
[no description available] | 2.15 | 1 | 0 | pyridines;
quinolone | antimicrobial agent;
antineoplastic agent |
4-chloroaniline
4-chloroaniline: RN given refers to parent cpd; structure. 4-chloroaniline : A chloroaniline in which the chloro atom is para to the aniline amino group. | 2.15 | 1 | 0 | chloroaniline;
monochlorobenzenes | |
1,4-naphthoquinone
naphthoquinone : A polycyclic aromatic ketone metabolite of naphthalene.. 1,4-naphthoquinone : The parent structure of the family of 1,4-naphthoquinones, in which the oxo groups of the quinone moiety are at positions 1 and 4 of the naphthalene ring. Derivatives have pharmacological properties. | 2.15 | 1 | 0 | 1,4-naphthoquinones | |
2-(2'-hydroxyphenyl)benzimidazole
2-(2'-hydroxyphenyl)benzimidazole: structure in first source | 2.15 | 1 | 0 | | |
6,7-Dimethyl-9-(2-acetoxyethyl)isoalloxazine
[no description available] | 2.15 | 1 | 0 | flavin | |
iridium
Iridium: A metallic element with the atomic symbol Ir, atomic number 77, and atomic weight 192.22. | 2.04 | 1 | 0 | cobalt group element atom;
platinum group metal atom | |
rhodium
Rhodium: A hard and rare metal of the platinum group, atomic number 45, atomic weight 102.905, symbol Rh.. rhodium atom : A cobalt group element atom of atomic number 45. | 2.04 | 1 | 0 | cobalt group element atom | |
chaetochromin
chaetochromin: from Chaetomium spp.; RN given refers to chaetochromin A | 2.15 | 1 | 0 | | |
benzofurazan
benzofurazan: structure | 2.15 | 1 | 0 | benzoxadiazole | |
4(5)-phenylimidazole
4(5)-phenylimidazole: tautomeric cpd; cytochrome P450 14alpha-sterol demethylase, CYP51 antagonist | 2.15 | 1 | 0 | | |
chrysomycin a
chrysomycin A: Streptomyces arenae; differs only in sugar moiety from gilvocarcin V | 2.15 | 1 | 0 | glycoside | |
2-phenylisatogen
2-phenylisatogen: inhibitor of mitochondrial oxidative phosphorylation; structure | 2.15 | 1 | 0 | | |
Porfiromycine
[no description available] | 2.15 | 1 | 0 | mitomycin | |
nsc228155
[no description available] | 2.15 | 1 | 0 | | |
1-(4-hydroxyphenyl)-3-(3-methoxyphenyl)thiourea
[no description available] | 2.15 | 1 | 0 | thioureas | |
arsenic
Arsenic: A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed) | 1.95 | 1 | 0 | metalloid atom;
pnictogen | micronutrient |
sodium artesunate
[no description available] | 2.1 | 1 | 0 | | |