2-nitroimidazole-1-acetohydroxamic acid profile

Cross-References

ID Source	ID
PubMed CID	159484
SCHEMBL ID	5312329
MeSH ID	M0161268

Synonyms (11)

Synonym
kih 801
n-hydroxy-2-nitro imidazole-1-acetamide
kih-801
1h-imidazole-1-acetamide, n-hydroxy-2-nitro-
117259-20-8
n-hydroxy-2-(2-nitroimidazol-1-yl)acetamide
AKOS006273708
kih-802
2-nitroimidazole-1-acetohydroxamic acid
SCHEMBL5312329
DTXSID80151746

Research

Studies (7)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	5 (71.43)	18.7374
1990's	2 (28.57)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.26

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.26 (24.57)
Research Supply Index	2.08 (2.92)
Research Growth Index	4.34 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.26)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	2 (28.57%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (71.43%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
thymine [no description available]	3.07	1	pyrimidine nucleobase; pyrimidone	Escherichia coli metabolite; human metabolite; mouse metabolite
etanidazole Etanidazole: A nitroimidazole that sensitizes hypoxic tumor cells that are normally resistant to radiation therapy.. etanidazole : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitro-1H-imidazol-1-yl)acetic acid with the amino group of ethanolamine. Used as a radiosensitising agent for hypoxic tumour cells.	3.76	3	C-nitro compound; imidazoles; monocarboxylic acid amide	alkylating agent; antineoplastic agent; prodrug; radiosensitizing agent
azomycin azomycin: RN given refers to parent cpd with specified locant; structure	4.97	7	C-nitro compound; imidazoles	antitubercular agent
misonidazole Misonidazole: A nitroimidazole that sensitizes normally radio-resistant hypoxic cells to radiation. It may also be directly cytotoxic to hypoxic cells and has been proposed as an antineoplastic.	4.68	5
1-(4'-hydroxy-2'-butenoxy)methyl-2-nitroimidazole 1-(4'-hydroxy-2'-butenoxy)methyl-2-nitroimidazole: structure given in first source	4.27	3

Condition	Relationship Strength	Studies
Anoxemia [description not available]	1.97	1
Hypoxia Sub-optimal OXYGEN levels in the ambient air of living organisms.	1.97	1
Experimental Neoplasms [description not available]	4.05	3

2-nitroimidazole-1-acetohydroxamic acid