Page last updated: 2024-12-07
2-naphthoylglycine
Description
2-naphthoylglycine: RN not in Chemline 8/18/82 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 129671 |
| CHEMBL ID | 8798 |
| SCHEMBL ID | 5632427 |
| MeSH ID | M0108289 |
Synonyms (24)
| Synonym |
|---|
| 2-naphthuric acid |
| 2-naphthoylglycine |
| AKOS000264527 |
| CHEMBL8798 , |
| 69826-63-7 |
| HMS1729L03 |
| bdbm50009982 |
| [(naphthalene-2-carbonyl)-amino]-acetic acid |
| 2-(naphthalene-2-carbonylamino)acetic acid |
| (2-naphthoylamino)acetic acid |
| 2-[(naphthalen-2-yl)formamido]acetic acid |
| EN300-08095 |
| glycine, n-(2-naphthalenylcarbonyl)- |
| glycine,n-(2-naphthalenylcarbonyl)- |
| 2-(naphthalen-2-ylformamido)acetic acid |
| DTXSID90220114 |
| SCHEMBL5632427 |
| sr-01000044843 |
| SR-01000044843-1 |
| (2-naphthoylamino)acetic acid # |
| Z56928566 |
| [(naphthalene-2-carbonyl)amino]acetic acid |
| 2-(2-naphthamido)acetic acid |
| 2-(2-naphthamido)aceticacid |
Protein Targets (1)
Inhibition Measurements
Bioassays (5)
| Assay ID | Title | Year | Journal | Article |
|---|
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3
| High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID34944 | Inhibition of aldose reductase from rat lens. Value ranges from 25-64 | 1989 | Journal of medicinal chemistry, May, Volume: 32, Issue:5
| Synthesis and in vitro aldose reductase inhibitory activity of compounds containing an N-acylglycine moiety. |
| AID35127 | Inhibition of partially purified aldose reductase obtained from rat lens (100 uM ); ND is No Data | 1989 | Journal of medicinal chemistry, May, Volume: 32, Issue:5
| Synthesis and in vitro aldose reductase inhibitory activity of compounds containing an N-acylglycine moiety. |
| AID34965 | Inhibitory activity against aldose reductase in rat lens | 1991 | Journal of medicinal chemistry, Jul, Volume: 34, Issue:7
| Relative structure-inhibition analyses of the N-benzoyl and N-(phenylsulfonyl) amino acid aldose reductase inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (4)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.72
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 12.72 (24.57) | | Research Supply Index | 1.79 (2.92) | | Research Growth Index | 4.51 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |