Compounds > 2-methylselenobenzanilide
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2-methylselenobenzanilide

Description

2-methylselenobenzanilide: metabolite of ebselen [MeSH]

Cross-References

ID SourceID
PubMed CID3080873
CHEMBL ID220461
SCHEMBL ID7343494
MeSH IDM0188449

Synonyms (10)

Synonym
2-(methylseleno)benzanilide
2-msbad
benzamide, 2-(methylseleno)-n-phenyl-
60940-24-1
2-methylselenobenzanilide
CHEMBL220461
2-methylselanyl-n-phenylbenzamide
SCHEMBL7343494
DTXSID90209767
2-methylseleno-n-phenylbenzamide

Bioassays (6)

Assay IDTitleYearJournalArticle
AID274140Inhibition of horseradish peroxidase at 100 uM2006Bioorganic & medicinal chemistry letters, Oct-15, Volume: 16, Issue:20
ISSN: 0960-894X		Horseradish peroxidase inhibition and antioxidant activity of ebselen and related organoselenium compounds.
AID274142Antioxidant activity assessed by singlet oxygen quenching ability2006Bioorganic & medicinal chemistry letters, Oct-15, Volume: 16, Issue:20
ISSN: 0960-894X		Horseradish peroxidase inhibition and antioxidant activity of ebselen and related organoselenium compounds.
AID274137Inhibition of horseradish peroxidase by spectrophotometric method2006Bioorganic & medicinal chemistry letters, Oct-15, Volume: 16, Issue:20
ISSN: 0960-894X		Horseradish peroxidase inhibition and antioxidant activity of ebselen and related organoselenium compounds.
AID274135Inhibition of gamma radiation-induced lipid peroxidation in liposomes2006Bioorganic & medicinal chemistry letters, Oct-15, Volume: 16, Issue:20
ISSN: 0960-894X		Horseradish peroxidase inhibition and antioxidant activity of ebselen and related organoselenium compounds.
AID274139Glutathione peroxidase activity assessed by GSH-GSSG coupled assay2006Bioorganic & medicinal chemistry letters, Oct-15, Volume: 16, Issue:20
ISSN: 0960-894X		Horseradish peroxidase inhibition and antioxidant activity of ebselen and related organoselenium compounds.
AID274138Effect on gamma irradiation-induced TBARS formation in liposomes at 50 uM2006Bioorganic & medicinal chemistry letters, Oct-15, Volume: 16, Issue:20
ISSN: 0960-894X		Horseradish peroxidase inhibition and antioxidant activity of ebselen and related organoselenium compounds.

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
ebselen
1
benzoselenazoleanti-inflammatory drug;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 3.5.4.1 (cytosine deaminase) inhibitor;
EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor;
enzyme mimic;
ferroptosis inhibitor;
genotoxin;
hepatoprotective agent;
neuroprotective agent;
radical scavenger		2006200618.0low000100
bis(2-(n-phenylcarboxamido)phenyl)diselenide
1
2006200618.0medium000100
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
aspirin
1
benzoic acids;
phenyl acetates;
salicylates		anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent		1991199133.0low001000
ebselen
4
benzoselenazoleanti-inflammatory drug;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 3.5.4.1 (cytosine deaminase) inhibitor;
EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor;
enzyme mimic;
ferroptosis inhibitor;
genotoxin;
hepatoprotective agent;
neuroprotective agent;
radical scavenger		1991199531.8high004000
thiazoles
1
1,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene		1992199232.0low001000
fura-2
1
1991199133.0low001000
2-phenyl-1,2-benzisothiazol-3-(2h)-one
1
1992199232.0medium001000
inositol 1,4,5-trisphosphate
1
myo-inositol trisphosphatemouse metabolite1991199133.0low001000
methimazole
1
1,3-dihydroimidazole-2-thionesantithyroid drug1995199529.0low001000
nadp
1
1995199529.0low001000
selenium
2
chalcogen;
nonmetal atom		micronutrient1991199133.0medium002000
2-selenylbenzanilide
1
1995199529.0high001000
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020