2-methylpyrrolidine

Description

2-Methylpyrrolidine is a cyclic secondary amine with a five-membered ring structure. It is a colorless liquid with a pungent odor and is soluble in water. It is used as a starting material for the synthesis of pharmaceuticals, pesticides, and other fine chemicals. 2-methylpyrrolidine is known to be a potent inhibitor of acetylcholinesterase, an enzyme that breaks down acetylcholine, a neurotransmitter involved in muscle contraction and memory. This property has led to research on its potential use as a therapeutic agent for Alzheimer's disease and other neurological disorders. 2-methylpyrrolidine is also a potent inhibitor of the enzyme monoamine oxidase, which is involved in the breakdown of neurotransmitters such as dopamine, norepinephrine, and serotonin. This property has led to research on its potential use as an antidepressant.'

2-methylpyrrolidine: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

2-methylpyrrolidine : A member of the class of pyrrolidines that is pyrrolidine which is substituted by a methyl group at position 2. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]