Substance | Relationship Strength | Studies | Trials | Classes | Roles |
catechol [no description available] | 2.41 | 1 | 0 | catechols | allelochemical; genotoxin; plant metabolite |
guaiacol Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747). methylcatechol : Any member of the class of catechols carrying one or more methyl substituents.. guaiacol : A monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position. | 2.41 | 1 | 0 | guaiacols | disinfectant; EC 1.1.1.25 (shikimate dehydrogenase) inhibitor; expectorant; plant metabolite |
imidazole imidazole: RN given refers to parent cpd. 1H-imidazole : An imidazole tautomer which has the migrating hydrogen at position 1. | 2.41 | 1 | 0 | imidazole | |
oxyquinoline Oxyquinoline: An antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics.. quinolin-8-ol : A monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes. | 2.41 | 1 | 0 | monohydroxyquinoline | antibacterial agent; antifungal agrochemical; antiseptic drug; iron chelator |
acetohydroxamic acid acetohydroxamic acid: urease inhibitor. oxime : Compounds of structure R2C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes; those from ketones may be called ketoximes.. N-hydroxyacetimidic acid : A carbohydroximic acid consisting of acetimidic acid having a hydroxy group attached to the imide nitrogen.. acetohydroxamic acid : A member of the class of acetohydroxamic acids that is acetamide in which one of the amino hydrogens has been replaced by a hydroxy group. | 2.41 | 1 | 0 | acetohydroxamic acids; carbohydroximic acid | algal metabolite; EC 3.5.1.5 (urease) inhibitor |
deferiprone Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.. deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia. | 2.41 | 1 | 0 | 4-pyridones | iron chelator; protective agent |
gaboxadol gaboxadol: GABA agonist; inhibitor of GABA uptake systems; structure | 2.17 | 1 | 0 | oxazole | |
benzimidazole 1H-benzimidazole : The 1H-tautomer of benzimidazole. | 7.03 | 1 | 0 | benzimidazole; polycyclic heteroarene | |
benzoxazolone benzoxazolone: RN given refers to parent cpd; structure. 2-benzoxazolinone : A member of the class of benzoxazoles that is 2,3-dihydro-1,3-benzoxazole carrying an oxo group at position 2. | 2.17 | 1 | 0 | benzoxazole | allelochemical; phytoalexin |
3-hydroxy-2-oxoindole 3-hydroxyindolin-2-one: structure in first source. 3-hydroxyindolin-2-one : An oxindole that is 1,3-dihydro-2H-indol-2-one substituted by a hydroxy group at position 3. | 2.07 | 1 | 0 | hydroxyindoles; oxindoles | |
barbituric acid barbituric acid: RN given refers to parent cpd; structure from Merck Index, 9th ed, #966. barbituric acid : A barbiturate, the structure of which is that of perhydropyrimidine substituted at C-2, -4 and -6 by oxo groups. Barbituric acid is the parent compound of barbiturate drugs, although it is not itself pharmacologically active. | 2.41 | 1 | 0 | barbiturates | allergen; xenobiotic |
4-toluenesulfonamide 4-toluenesulfonamide: RN given refers to parent cpd. toluene-4-sulfonamide : A sulfonamide that is benzenesulfonamide bearing a methyl group at position 4. | 2.41 | 1 | 0 | sulfonamide | |
isatin tribulin: endogenous MONOAMINE OXIDASE inhibitory activity extractable into ethyl acetate found in brain and many mammalian tissues and fluids; ISATIN is a major component; produced in excess following alcohol withdrawal; | 2.17 | 1 | 0 | indoledione | EC 1.4.3.4 (monoamine oxidase) inhibitor; plant metabolite |
benzenesulfonamide [no description available] | 2.41 | 1 | 0 | sulfonamide | |
2-aminobenzothiazole [no description available] | 2.17 | 1 | 0 | benzothiazoles | |
hydantoins Hydantoins: Compounds based on imidazolidine dione. Some derivatives are ANTICONVULSANTS.. imidazolidine-2,4-dione : An imidazolidinone with oxo groups at position 2 and 4. | 2.41 | 1 | 0 | imidazolidine-2,4-dione | |
lysidine lysidine: structure in first source; do not confuse with the imidazole-derivative known as lysidine. lysidine : Cytidine in which the 2-keto group on the cytosine ring is substituted by an epsilon-Llysyl residue. | 2.41 | 1 | 0 | | |
8-aminoquinoline [no description available] | 2.41 | 1 | 0 | | |
1,2-Dihydroquinolin-2-imine [no description available] | 2.41 | 1 | 0 | aminoquinoline | |
4-methylimidazole 4-methylimidazole: RN given refers to parent cpd. 4-methylimidazole : Imidazole substituted at position 4 by a methyl group. | 2.41 | 1 | 0 | imidazoles | carcinogenic agent; reaction intermediate |
2-hydroxybenzothiazole 2-hydroxybenzothiazole : Benzothiazole substituted with a hydroxy group at the 2-position. | 2.41 | 1 | 0 | benzothiazole | |
pyromeconic acid pyromeconic acid: from herb Dengzhanhua; structure | 2.41 | 1 | 0 | | |
serinol serinol: RN given refers to cpd without isomeric designation | 2.41 | 1 | 0 | | |
1-hydroxy-2(1h)-pyridinone 1-hydroxy-2(1H)-pyridinone: structure in first source | 2.41 | 1 | 0 | | |
8-hydroxy-2-quinolinecarboxylic acid [no description available] | 2.41 | 1 | 0 | quinolines | |
1-phenylimidazole 1-phenylimidazole: ligand for cytochrome P-450 & inhibitor of microsomal oxidation | 2.41 | 1 | 0 | | |
3-indazolinone 3-indazolinone: structure given in first source | 2.17 | 1 | 0 | | |
5-Chloro-1H-indole-2,3-dione [no description available] | 2.17 | 1 | 0 | indoles | anticoronaviral agent |
1-methyl-3-hydroxypyridine-2-one [no description available] | 2.41 | 1 | 0 | | |
2-acetylcyclopentanone 2-acetylcyclopentanone: an enolate-forming compound that is protective against electrophilic drugs; structure in first source | 2.41 | 1 | 0 | | |
8-(methylsulfonylamino)quinoline 8-(methylsulfonylamino)quinoline: has diabetogenic properties; structure given in first source | 2.41 | 1 | 0 | | |
hydroxyl radical Hydroxyl Radical: The univalent radical OH. Hydroxyl radical is a potent oxidizing agent. | 2.03 | 1 | 0 | oxygen hydride; oxygen radical; reactive oxygen species | |
5-Fluoroisatin [no description available] | 2.17 | 1 | 0 | indoles | anticoronaviral agent |
2-mercaptobenzimidazole 2-mercaptobenzimidazole: purine synthesis antimetabolite; RN given refers to parent cpd | 2.66 | 2 | 0 | | |
3-hydroxyquinolin-2(1h)-one 3-hydroxyquinolin-2(1H)-one: structure in first source. dihydroxyquinoline : Any hydroxyquinoline in which the number of hydroxy substituents is specified as two. | 2.17 | 1 | 0 | hydroxyquinoline; quinolone | |
thiohydantoins Thiohydantoins: Sulfur analogs of hydantoins with one or both carbonyl groups replaced by thiocarbonyl groups. | 2.41 | 1 | 0 | | |
6-Chlorobenzo[d]isoxazol-3-ol [no description available] | 2.17 | 1 | 0 | benzisoxazole | |
4-hydroxyquinazoline 4-oxo-3,4-dihydroquinazoline: structure in first source | 2.03 | 1 | 0 | quinazolines | |
4,5-dihydro-1h-1,2,4-triazol-5-one 4,5-dihydro-1H-1,2,4-triazol-5-one: a 1,2,4-triazole derivative; structure given in first source | 2.41 | 1 | 0 | | |