Page last updated: 2024-11-07

2-hydroxy-7-methoxy-2h-1,4-benzoxazin-3-one

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2-hydroxy-7-methoxy-2H-1,4-benzoxazin-3-one: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID152213
CHEMBL ID451316
CHEBI ID179371
SCHEMBL ID914279
MeSH IDM0105546

Synonyms (17)

Synonym
2-hydroxy-7-methoxy-2h-1,4-benzoxazin-3(4h)-one
17359-53-4
CHEBI:179371
2-hydroxy-7-methoxy-4h-1,4-benzoxazin-3-one
hmboa
2-hydroxy-7-methoxy-1,4-benzoxazin-3-one
CHEMBL451316
2h-1,4-benzoxazin-3(4h)-one, 2-hydroxy-7-methoxy-
2-hydroxy-7-methoxy-2h-1,4-benzoxazin-3-one
SCHEMBL914279
2-hydroxy-7-methoxy-3,4-dihydro-2h-1,4-benzoxazin-3-one
7-methoxy-2h-1,4-benzoxazine-2,3-diol
DTXSID30938408
BCP31439
2-hydroxy-7-methoxy-1,4-benzoxazin-3-one; 2h-1,4-benzoxazin-3(4h)-one, 2-hydroxy-7-methoxy-
A904257
2-hydroxy-7-methoxy-2h-benzo[b][1,4]oxazin-3(4h)-one
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
benzoxazine
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID1103171Antifeedant activity against third-instar larvae of Rhopalosiphum padi assessed as repellency index after 24 hr by feeding choice assay2004Journal of agricultural and food chemistry, May-05, Volume: 52, Issue:9
Chemical basis for the antifeedant activity of natural hydroxamic acids and related compounds.
AID338667Antiinflammatory activity in Wistar rat peritoneal mast cells assessed as inhibition of concanavalin A-induced histamine release treated 10 mins before concanavalin A challenge measured after 30 mins
AID338669Antiinflammatory activity in Wistar rat peritoneal mast cells assessed as inhibition of IgE-induced histamine release at 1000 uM treated 10 mins before IgE challenge measured after 5 mins
AID338668Antiinflammatory activity in Wistar rat peritoneal mast cells assessed as inhibition of concanavalin A-induced histamine release at 1000 uM treated 10 mins before concanavalin A challenge measured after 30 mins
AID1585947Antifungal activity against Candida albicans after 24 hrs by spectrophotometric method2018Bioorganic & medicinal chemistry, 12-15, Volume: 26, Issue:23-24
QSAR of 1,4-benzoxazin-3-one antimicrobials and their drug design perspectives.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (4)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.36

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.36 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.16 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.36)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]