Compounds > 2-hydroxy-5-(trifluoromethyl)pyridine
Page last updated: 2024-11-07

2-hydroxy-5-(trifluoromethyl)pyridine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2-hydroxy-5-(trifluoromethyl)pyridine: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID147443
SCHEMBL ID525257
MeSH IDM0357644

Synonyms (58)

Synonym
33252-63-0
2-hydroxy-5-(trifluoromethyl)pyridine, 97%
MAYBRIDGE1_006426 ,
SR-01000639040-1
5-(trifluoromethyl)-2-pyridone
T2539
5-(trifluoromethyl)-2-pyridinone
2-hydroxy-5-trifluoromethylpyridine
2-hydroxy-5-(trifluoromethyl)pyridine
HMS559M02
AKOS005145592
5-(trifluoromethyl)pyridin-2-ol
5-(trifluoromethyl)-1h-pyridin-2-one
AKOS001054750
A5938
unii-1ccp81h07b
2h-5tfmp
1ccp81h07b ,
2(1h)-pyridinone, 5-(trifluoromethyl)-
5-(trifluoromethyl)-2(1h)-pyridinone
5-(trifluoromethyl)-1,2-dihydropyridin-2-one
5-trifluoromethyl-pyridin-2-ol
5-(trifluoromethyl)-2-pyridinol
5-trifluoromethyl-2-(1h)-pyridinone
CCG-49593
5-(trifluoromethyl)pyridin-2(1h)-one
BP-20272
FT-0612553
79894-13-6
FS-2555
AM20070045
RB1047
CS-B0101
SCHEMBL525257
5E-502
mfcd00042315
SY007020
5-(trifluoromethyl) pyridin-2-ol
5-trifluoromethyl-2(1h)-pyridone
5-(trifloromethyl)-2(1h)-pyridone
5-trifluoromethyl-2-pyridone
5-(trifluoromethyl)-2-(1h)-pyridone
5-trifluoromethyl-2-pyridinol
DTXSID8044387
5-trifluoromethyl-2-hydroxypyridine
trifluoromethyl)-2(1h)-pyridinone, 5-(
AC-9476
Z56910389
5-trifluoromethylpyrid-2-one
STL554352
fluazifop-p-butyl metabolite 10
BBL100558
Q27252234
yzuqzfucrslken-uhfffaoysa-n
juvojlxgvhwbeo-uhfffaoysa-n
EN300-05018
u4d ,
5-(trifluoromethyl)pyridin-2-one

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
"Directly coupled HPLC-NMR-MS was used to characterize two major metabolites of 5-trifluoromethylpyridone (2-hydroxy-5-trifluoromethylpyridine), a model compound for herbicides, after it had been dosed into hydroponically grown maize plants."( Application of directly coupled HPLC-NMR-MS/MS to the identification of metabolites of 5-trifluoromethylpyridone (2-hydroxy-5-trifluoromethylpyridine) in hydroponically grown plants.
Bailey, NJ; Cooper, P; Hadfield, ST; Lenz, EM; Lindon, JC; Nicholson, JK; Stanley, PD; Taylor, SD; Wilson, ID; Wright, B, 2000)		0.31
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).2014Journal of biomolecular screening, Jul, Volume: 19, Issue:6
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.53

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.53 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.53)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
fluazifop-butyl
fluazifop-butyl: RN given for cpd without isomeric designation. fluazifop-butyl : A racemate that is the butyl ester of fluazifop. It is used as a post-emergence herbicide for the control grass weeds in various broad-leaved crops.. butyl 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoate : A carboxylic ester resulting from the formal condensation of the carboxy group 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid with the hydroxy group of butan-1-ol.		2.1110aromatic ether;
carboxylic ester;
organofluorine compound;
pyridines
ConditionIndicatedRelationship StrengthStudiesTrials
Plasmodium falciparum Malaria
[description not available]		02.110
Malaria, Falciparum
Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.		02.110
Anemia, Fanconi
[description not available]		02.1310
Fanconi Anemia
Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)		02.1310