2-fluoro-2-deoxy-d-glucose profile

2-deoxy-2-fluoromannose: RN given refers to (D)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	170049
CHEMBL ID	1908940
CHEBI ID	49135
SCHEMBL ID	38895
MeSH ID	M0029361

Synonym
fludeoxyglucose
(2r,3s,4r,5r)-2-fluoro-3,4,5,6-tetrahydroxyhexanal
CHEBI:49135 ,
2-deoxy-2-fluoro-aldehydo-d-glucose
2-fluoro-2-deoxy-d-glucose ,
AKOS006272985
D3023
A820014
29702-43-0
2-fluoro-3,4,5,6-tetrahydroxy-hexanal
2-deoxy-2-fluoromannose
fludeoxyglucose [usp-rs]
fludeoxyglucose [vandf]
.alpha.-d-glucopyranose, 2-deoxy-2-fluoro
d-glucose, 2-deoxy-2-fluoro-
ZO2JV75L55 ,
SCHEMBL38895
c6h11fo5
W-202232
CHEMBL1908940
alpha-d-glucopyranose, 2-deoxy-2-fluoro
unii-zo2jv75l55
2-fluoro-2-deoxy-d-glucopyranose
AS-59436
Q27121494
DTXSID701311592
CS-0182797
HY-141637

Class	Description
2-deoxy-2-fluoro-D-glucose	A monosaccharide derivative that is glucose in which the hydroxy group at position 2 is replaced by fluorine.
aldehyde	A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	9 (45.00)	18.7374
1990's	6 (30.00)	18.2507
2000's	2 (10.00)	29.6817
2010's	3 (15.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (5.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	19 (95.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
pentetic acid Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.	1.97	1	pentacarboxylic acid	copper chelator
fluorouracil Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.. 5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.	7	1	nucleobase analogue; organofluorine compound	antimetabolite; antineoplastic agent; environmental contaminant; immunosuppressive agent; radiosensitizing agent; xenobiotic
mannose mannopyranose : The pyranose form of mannose.	2.03	1	D-aldohexose; D-mannose; mannopyranose	metabolite
technetium Technetium: The first artificially produced element and a radioactive fission product of URANIUM. Technetium has the atomic symbol Tc, and atomic number 43. All technetium isotopes are radioactive. Technetium 99m (m=metastable) which is the decay product of Molybdenum 99, has a half-life of about 6 hours and is used diagnostically as a radioactive imaging agent. Technetium 99 which is a decay product of technetium 99m, has a half-life of 210,000 years.	3.06	1	manganese group element atom
fluorine Fluorine: A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as fluoride (FLUORIDES) to prevent dental caries.	4.58	8	diatomic fluorine; gas molecular entity	NMR chemical shift reference compound
rhamnose [no description available]	5.43	20	L-rhamnose
fluorides [no description available]	1.96	1	halide anion; monoatomic fluorine
fluorodeoxyglucose f18 Fluorodeoxyglucose F18: The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162)	4.86	11	2-deoxy-2-((18)F)fluoro-D-glucose; 2-deoxy-2-fluoro-aldehydo-D-glucose
deoxyglucose Deoxyglucose: 2-Deoxy-D-arabino-hexose. An antimetabolite of glucose with antiviral activity.. deoxyglucose : A deoxyhexose comprising glucose having at least one hydroxy group replaced by hydrogen.	4.86	11
3-deoxy-3-fluoro-d-glucose [no description available]	3.77	3
coenzyme q10 coenzyme Q10: Ubiquinone ring with a chain of 10 isoprene units; redox equilibrium with ubiqunol serving in mitochondrial inner membrane to transfer electrons; presence during reconstitution of acetylcholine receptor into phospholipid vesicles yields vesicles active in catalyzing carbamylcholine-sensitive Na+ flux; coenzyme Q10 depletion has been noted with use of statins. coenzyme Q10 : A ubiquinone having a side chain of 10 isoprenoid units. In the naturally occurring isomer, all isoprenyl double bonds are in the E- configuration.	1.97	1	ubiquinones	antioxidant; ferroptosis inhibitor; human metabolite
ubiquinone Ubiquinone: A lipid-soluble benzoquinone which is involved in ELECTRON TRANSPORT in mitochondrial preparations. The compound occurs in the majority of aerobic organisms, from bacteria to higher plants and animals.	1.97	1
guanosine diphosphate Guanosine Diphosphate: A guanine nucleotide containing two phosphate groups esterified to the sugar moiety.	1.96	1	guanosine 5'-phosphate; purine ribonucleoside 5'-diphosphate	Escherichia coli metabolite; mouse metabolite; uncoupling protein inhibitor

Condition	Relationship Strength	Studies
Hepatocellular Carcinoma [description not available]	2.08	1
Cancer of Liver [description not available]	3.31	2
Carcinoma, Hepatocellular A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.	2.08	1
Liver Neoplasms Tumors or cancer of the LIVER.	3.31	2
Atherogenesis [description not available]	2.1	1
Atheroma [description not available]	2.1	1
Atherosclerosis A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.	2.1	1
Carcinoma, Epidermoid [description not available]	1.96	1
Experimental Hepatoma [description not available]	2.38	2
Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)	1.96	1
Fibrosarcoma A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)	2	1
Brain Disorders [description not available]	1.97	1
Benign Neoplasms, Brain [description not available]	1.97	1
Brain Hemorrhage, Cerebral [description not available]	1.97	1
Anterior Choroidal Artery Infarction [description not available]	1.97	1
Brain Diseases Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.	1.97	1
Brain Neoplasms Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.	1.97	1
Cerebral Hemorrhage Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.	1.97	1
Cerebral Infarction The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).	1.97	1
Sarcoma 180 An experimental sarcoma of mice.	1.97	1
Cell Transformation, Viral An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus.	1.96	1

2-fluoro-2-deoxy-d-glucose

Description

Cross-References

Synonyms (28)

Drug Classes (2)

Research

Studies (20)

Market Indicators

Research Demand Index: 47.08

Study Types

2-fluoro-2-deoxy-d-glucose

Description

Cross-References

Synonyms (28)

Drug Classes (2)

Research

Studies (20)

Market Indicators

Research Demand Index: 47.08

Study Types

Related Drugs (13)

Related Conditions (21)