Page last updated: 2024-11-13

2-ethylhexyl 2,3,4,5-tetrabromobenzoate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2-ethylhexyl 2,3,4,5-tetrabromobenzoate: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID71316600
SCHEMBL ID2728830
MeSH IDM0578954

Synonyms (21)

Synonym
FT-0668285
benzoic acid, 2,3,4,5-tetrabromo-, 2-ethylhexyl ester
2-ethylhexyltetrabromobenzoate
2-ethylhexyl-2,3,4,5-tetrabromobenzoate
firemaster 550 component
2,3,4,5-tetrabromobenzoic acid 2-ethylhexyl ester
2-ethylhexyl 2,3,4,5-tetrabromobenzoate
183658-27-7
SCHEMBL2728830
DTXSID9052686
AKOS027323847
J-011768
benzoic acid, 2,3,4,5-tetrabromo-, 2-ethylhexyl ester (tbb)
Q20054520
A929326
SY261702
mfcd26960592
2-ethylhexyl 2,3,4,5-tetrabromobenzoate(tbb)
CS-0449217
2-ethylhexyl2,3,4,5-tetrabromobenzoate
2-ethylhexyl-2,3,4,5-tetrabromobenzoate (tbb)

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" Induction of CYP3A4 might cause undesired drug-drug interactions, lower bioavailability of pharmaceutical drugs, higher formation of reactive toxic metabolites, or enhanced elimination of endogenous hormones, such as T3/T4, to lead to endocrine disruption."( New brominated flame retardants and their metabolites as activators of the pregnane X receptor.
Carino, A; Distrutti, E; Fiorucci, S; Gramec Skledar, D; Peterlin Mašič, L; Tomašič, T, 2016
)
0.43

Dosage Studied

ExcerptRelevanceReference
" Both compounds were detected in fish carcasses at 76% and 2% of the daily dosage of BTBPE and EH-TBB, respectively, indicating accumulation of BTBPE and by contrast extensive depuration/metabolism of EH-TBB."( Effects of food-borne exposure of juvenile rainbow trout (Oncorhynchus mykiss) to emerging brominated flame retardants 1,2-bis(2,4,6-tribromophenoxy)ethane and 2-ethylhexyl-2,3,4,5-tetrabromobenzoate.
Douville, M; Giraudo, M; Houde, M; Letcher, RJ, 2017
)
0.46
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (22)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (9.09)29.6817
2010's20 (90.91)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 20.19

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index20.19 (24.57)
Research Supply Index3.14 (2.92)
Research Growth Index5.70 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (20.19)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other22 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]