2-ethyl-2-oxazoline profile

2-Ethyl-2-oxazoline is a heterocyclic compound that has been studied for its potential use as a building block in organic synthesis. It is a versatile reagent that can be used to synthesize a variety of other compounds, including pharmaceuticals and agricultural chemicals. The compound is typically synthesized through a ring-closing reaction involving an amino alcohol and an aldehyde or ketone. The synthesis can be performed in various ways, such as by using a Lewis acid catalyst or under microwave irradiation. 2-Ethyl-2-oxazoline exhibits a variety of pharmacological effects, including anti-inflammatory, analgesic, and antimicrobial activity. The compound's potential applications in these areas are being investigated. 2-Ethyl-2-oxazoline is studied because it is a versatile building block for organic synthesis and its potential applications in various fields, such as pharmaceuticals and agriculture. Researchers are exploring its chemical reactivity and its ability to form new compounds with desirable properties. '

2-ethyl-2-oxazoline: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	66412
MeSH ID	M0550843

Synonym
2-ethyloxazoline
nsc-136557
10431-98-8
2-oxazoline, 2-ethyl-
nsc136557
2-ethyl-2-oxazoline
oxazole,5-dihydro-
oxazole, 2-ethyl-4,5-dihydro-
inchi=1/c5h9no/c1-2-5-6-3-4-7-5/h2-4h2,1h
2-ethyl-2-oxazoline, >=99%
2-ethyl-4,5-dihydro-1,3-oxazole
E0373
2-ethyl-4,5-dihydrooxazole
A800954
25805-17-8
einecs 233-912-4
unii-b8cd92t4p5
nsc 136557
b8cd92t4p5 ,
FT-0612270
AKOS015912733
2-ethyl-4,5-dihydro-oxazole
AM84318
Z-1053
ethyl oxazoline
DTXSID9065075
2-ethyl-4,5-dihydro-1,3-oxazole #
W-110272
FT-0699359
F0001-0097
mfcd00005302
Q26218964
E78873
STARBLD0019600
SY011237

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	10 (71.43)	24.3611
2020's	4 (28.57)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	14 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
lactic acid Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed). 2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.	2.11	1	2-hydroxy monocarboxylic acid	algal metabolite; Daphnia magna metabolite
dilactide dilactide: structure given in first source	2.11	1	dioxanes
aziridine [no description available]	2.06	1	azacycloalkane; aziridines; saturated organic heteromonocyclic parent	alkylating agent
oxazoles Oxazoles: Five-membered heterocyclic ring structures containing an oxygen in the 1-position and a nitrogen in the 3-position, in distinction from ISOXAZOLES where they are at the 1,2 positions.. 1,3-oxazole : A five-membered monocyclic heteroarene that is an analogue of cyclopentadiene with O in place of CH2 at position 1 and N in place of CH at position 3.. oxazole : An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom.	4.14	14	1,3-oxazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
thiazoles [no description available]	2.05	1	1,3-thiazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
caprolactone hexano-6-lactone : A epsilon-lactone that is oxepane substituted by an oxo group at position 2.	2.15	1	epsilon-lactone
d-alpha tocopherol Vitamin E: A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.. tocopherol : A collective name for a group of closely related lipids that contain a chroman-6-ol nucleus substituted at position 2 by a methyl group and by a saturated hydrocarbon chain consisting of three isoprenoid units. They are designated as alpha-, beta-, gamma-, and delta-tocopherol depending on the number and position of additional methyl substituents on the aromatic ring. Tocopherols occur in vegetable oils and vegetable oil products, almost exclusively with R,R,R configuration. Tocotrienols differ from tocopherols only in having three double bonds in the hydrocarbon chain.. vitamin E : Any member of a group of fat-soluble chromanols that exhibit biological activity against vitamin E deficiency. The vitamers in this class consists of a chroman-6-ol core which is substituted at position 2 by a methyl group and (also at position 2) either a saturated or a triply-unsaturated hydrocarbon chain consisting of three isoprenoid units. The major function of vitamin E is to act as a natural antioxidant by scavenging free radicals and molecular oxygen.. (R,R,R)-alpha-tocopherol : An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils.	2.11	1	alpha-tocopherol	algal metabolite; antiatherogenic agent; anticoagulant; antioxidant; antiviral agent; EC 2.7.11.13 (protein kinase C) inhibitor; immunomodulator; micronutrient; nutraceutical; plant metabolite
glutamic acid Glutamic Acid: A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.. glutamic acid : An alpha-amino acid that is glutaric acid bearing a single amino substituent at position 2.	2.21	1	glutamic acid; glutamine family amino acid; L-alpha-amino acid; proteinogenic amino acid	Escherichia coli metabolite; ferroptosis inducer; micronutrient; mouse metabolite; neurotransmitter; nutraceutical
irinotecan [no description available]	2.21	1	carbamate ester; delta-lactone; N-acylpiperidine; pyranoindolizinoquinoline; ring assembly; tertiary alcohol; tertiary amino compound	antineoplastic agent; apoptosis inducer; EC 5.99.1.2 (DNA topoisomerase) inhibitor; prodrug
thiazolyl blue thiazolyl blue: RN & II refers to bromide. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide : The bromide salt of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium.	2.05	1	organic bromide salt	colorimetric reagent; dye
2-methyl-2-oxazoline 2-methyl-2-oxazoline: structure in first source. 2-methyl-2-oxazoline : A 5-membered heterocyclic compound, which is substituted in the 2-position with a methyl group and which is often used as a monomer in polymerisation reactions.	2.5	2	oxazoline
tocophersolan tocophersolan: RN given refers to parent cpd	2.11	1	tocol
artesunic acid [no description available]	2.25	1
calcitonin [no description available]	7.25	1

Condition	Relationship Strength	Studies
Cancer of Colon [description not available]	2.25	1
Colonic Neoplasms Tumors or cancer of the COLON.	2.25	1
Glial Cell Tumors [description not available]	2.15	1
Glioma Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)	2.15	1
Colorectal Cancer [description not available]	2.21	1
Colorectal Neoplasms Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.	2.21	1

2-ethyl-2-oxazoline

Description

Cross-References

Synonyms (35)

Research

Studies (14)

Market Indicators

Research Demand Index: 39.49

Study Types