Compounds > 2-dimethylamino-3-chloro-1,4-naphthoquinone
Page last updated: 2024-12-06

2-dimethylamino-3-chloro-1,4-naphthoquinone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2-dimethylamino-3-chloro-1,4-naphthoquinone is a synthetic compound with potential biological activity. It is a derivative of 1,4-naphthoquinone, a class of compounds known for their diverse pharmacological properties. Research on this compound often focuses on its potential as an anticancer agent, particularly due to its ability to interfere with cell growth and induce apoptosis. However, further studies are needed to fully understand its mechanisms of action and potential therapeutic applications.'

2-dimethylamino-3-chloro-1,4-naphthoquinone: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID21448
SCHEMBL ID2462086
MeSH IDM0139603

Synonyms (22)

Synonym
STL356139
1,4-naphthoquinone, 2-chloro-3-(dimethylamino)-
1,4-naphthalenedione, 2-chloro-3-(dimethylamino)-
brn 2727225
nsc 7
wln: l66 bv evj cn1&1 dg
5350-26-5
nsc-7
1, 2-chloro-3-(dimethylamino)-
2-dimethylamino-3-chloro-1,4-naphthoquinone
nsc7
2-chloro-3-(dimethylamino)-1,4-naphthoquinone
2-chloro-3-(dimethylamino)naphthalene-1,4-dione
AKOS003233484
unii-xed3nk8cxf
xed3nk8cxf ,
AB00080142-01
2-chloro-3-(dimethylamino)naphthoquinone
SCHEMBL2462086
DTXSID20201714
2-chloro-3-(dimethylamino)-1,4-dihydronaphthalene-1,4-dione
CS-0365192
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.63

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.63 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.42 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.63)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
5,5-dimethyl-1-pyrroline-1-oxide
5,5-dimethyl-1-pyrroline-1-oxide: do not confuse with DMPO (4',5'-dihydroxy-7-methoxy-4-phenyl-5,2'-oxidocoumarin). 5,5-dimethyl-1-pyrroline N-oxide : A member of the class of 1-pyrroline nitrones (1-pyrroline N-oxides) resulting from the formal N-oxidation of 5,5-dimethyl-1-pyrroline. Used as a spin trap for the study of radicals formed by enzymatic acetaldehyde oxidation.		1.99101-pyrroline nitronesneuroprotective agent;
spin trapping reagent
adrenochrome
Adrenochrome: Pigment obtained by the oxidation of epinephrine.		1.9910indoles
aminopyrine
Aminopyrine: A pyrazolone with analgesic, anti-inflammatory, and antipyretic properties but has risk of AGRANULOCYTOSIS. A breath test with 13C-labeled aminopyrine has been used as a non-invasive measure of CYTOCHROME P-450 metabolic activity in LIVER FUNCTION TESTS.. aminophenazone : A pyrazolone that is 1,2-dihydro-3H-pyrazol-3-one substituted by a dimethylamino group at position 4, methyl groups at positions 1 and 5 and a phenyl group at position 2. It exhibits analgesic, anti-inflammatory, and antipyretic properties.		1.9610pyrazolone;
tertiary amino compound		antipyretic;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
3,4-xylidine
3,4-dimethylaniline : A primary arylamine that is aniline in which the hydrogens at the 3- and 4-positions are replaced by methyl groups. A low-melting, crystalline solid, it is used in the production of vitamin B2, dyes, pesticides and other chemicals.		2.0610dimethylaniline;
primary arylamine
daunorubicin
Daunorubicin: A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of LEUKEMIA and other NEOPLASMS.. anthracycline : Anthracyclines are polyketides that have a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine.. daunorubicin : A natural product found in Actinomadura roseola.		1.9710aminoglycoside antibiotic;
anthracycline;
p-quinones;
tetracenequinones		antineoplastic agent;
bacterial metabolite
naphthoquinones
Naphthoquinones: Naphthalene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.		3.0950
ConditionIndicatedRelationship StrengthStudiesTrials