2-Chlorobenzyl chloride, also known as o-chlorobenzyl chloride, is a colorless liquid with a pungent odor. It is a versatile chemical intermediate used in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and dyes. Its synthesis typically involves the chlorination of o-chlorotoluene. 2-Chlorobenzyl chloride exhibits a range of biological activities, including antibacterial and antifungal properties. Its importance stems from its role in the production of important chemicals, its potential for further development as a bioactive compound, and its utility in chemical research. Research on 2-Chlorobenzyl chloride focuses on its synthesis, reactivity, biological activity, and potential applications.'
2-chlorobenzyl chloride: inhibits growth of Saccharomyces cerevisiae & lowers the contents of fatty acids & sterols [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 11906 |
| CHEMBL ID | 3187054 |
| SCHEMBL ID | 126469 |
| MeSH ID | M0087664 |
| Synonym |
|---|
| a,2-dichlorotoluene |
| o,.alpha.-dichlorotoluene |
| nsc8446 |
| .alpha.,2-dichlorotoluene |
| nsc-8446 |
| .alpha.,o-dichlorotoluene |
| 1-chloro-2-(chloromethyl)benzene |
| 611-19-8 |
| o-chlorobenzyl chloride |
| benzene, 1-chloro-2-(chloromethyl)- |
| 2-chlorobenzyl chloride |
| ortho-.alpha.-dichlorotoluene |
| toluene, o,.alpha.-dichloro- |
| alpha,2-dichlorotoluene |
| ar,alpha-dichlorotoluene |
| ai3-14885 |
| toluene, ar,alpha-dichloro- |
| ortho-alpha-dichlorotoluene |
| toluene, alpha,o-dichloro- |
| toluene, o,alpha-dichloro- |
| einecs 210-258-8 |
| nsc 8446 |
| brn 0471700 |
| alpha,o-dichlorotoluene |
| benzene, chloro(chloromethyl)- |
| 2-chlorobenzyl chloride, >=99% |
| 2-chlorobenzyl chloride, >=98% |
| NCGC00164081-01 |
| D0420 |
| AKOS000119336 |
| A833049 |
| NCGC00164081-02 |
| 2-chlorobenzylchloride |
| dtxcid707241 |
| dtxsid3027241 , |
| cas-611-19-8 |
| tox21_201089 |
| NCGC00258641-01 |
| STL163635 |
| BBL012560 |
| 40795-52-6 |
| ec 210-258-8 |
| ortho-chlorobenzyl chloride |
| h58di83rmd , |
| unii-h58di83rmd |
| FT-0611925 |
| FT-0611660 |
| 1-chloro-2-chloromethyl-benzene |
| AM101018 |
| SCHEMBL126469 |
| 2-chloro benzylchloride |
| 2-chloromethylchlorobenzene |
| 2-chorobenzyl chloride |
| 2-chloro benzyl chloride |
| 2-chlorobenzyl-chloride |
| W-105192 |
| 2,alpha-dichlorotoluene |
| 2,.alpha.-dichlorotoluene |
| toluene, .alpha.,2-dichloro- |
| CHEMBL3187054 |
| F2190-0261 |
| 11-19-8 |
| mfcd00000893 |
| 1-chloro-2-chloromethylbenzene |
| BCP25774 |
| VS-03389 |
| EN300-18204 |
| Q27279668 |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| AR protein | Homo sapiens (human) | Potency | 34.0491 | 0.0002 | 21.2231 | 8,912.5098 | AID1259243; AID743036; AID743053 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (34.36) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||