Page last updated: 2024-12-06
2-aminobenzonitrile
Description
2-Aminobenzonitrile, also known as 2-cyanophenylamine, is a key intermediate in the synthesis of various pharmaceuticals, agrochemicals, and dyes. It's typically synthesized through the nitration of toluene followed by reduction and cyanation. Its versatile structure allows for modifications leading to diverse derivatives with various applications. Research studies focus on its potential in medicinal chemistry, particularly as a building block for anti-cancer agents and inhibitors of specific enzymes. The compound exhibits fluorescence properties and is investigated for its potential applications in organic light-emitting diodes (OLEDs) and other optoelectronic devices. '
o-aminobenzonitrile: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 72913 |
| CHEMBL ID | 3561681 |
| SCHEMBL ID | 71324 |
| MeSH ID | M000605722 |
Synonyms (49)
| Synonym |
|---|
| aminobenzonitrile |
| einecs 217-549-9 |
| brn 0907187 |
| o-aminobenzonitrile |
| 2-cyanoaniline |
| o-cyanoaniline |
| 2-amino-benzonitrile |
| 1885-29-6 |
| 2-aminobenzonitrile , |
| anthranilonitrile |
| inchi=1/c7h6n2/c8-5-6-3-1-2-4-7(6)9/h1-4h,9h |
| benzonitrile, 2-amino- |
| 2-aminobenzonitrile, 98% |
| A0861 |
| STK802207 |
| AKOS000120456 |
| unii-5rxh2b211r |
| 4-14-00-01013 (beilstein handbook reference) |
| 5rxh2b211r , |
| FT-0611231 |
| 2-cyano-1-aminobenzene |
| AM20060057 |
| 2-aminobenzenecarbonitrile |
| BP-21336 |
| SCHEMBL71324 |
| 2-amino benzonitrile |
| 2-aminobenzo nitrile |
| 2- aminobenzenecarbonitrile |
| 2-amino-1-cyano-benzene |
| tox21_304036 |
| dtxsid9051824 , |
| cas-1885-29-6 |
| NCGC00357243-01 |
| dtxcid4030380 |
| W-107755 |
| benzonitrile, amino- |
| AN-584/40186357 |
| benzonitrile, o-amino- |
| CHEMBL3561681 |
| mfcd00007631 |
| F0020-1996 |
| D70483 |
| AS-10868 |
| 2-cyanoaniline;o-aminobenzonitrile |
| BCP33252 |
| CS-W013598 |
| Q27262788 |
| EN300-20429 |
| Z104478174 |
Protein Targets (2)
Potency Measurements
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 34.60
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 34.60 (24.57) | | Research Supply Index | 1.79 (2.92) | | Research Growth Index | 4.99 (4.65) | | Search Engine Demand Index | 40.31 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |