Page last updated: 2024-12-05

2-amino-6-nitrotoluene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID11783
CHEMBL ID1882292
SCHEMBL ID190550
SCHEMBL ID15630321
MeSH IDM0115706

Synonyms (64)

Synonym
AC-2973
d3jc433ceb ,
4-12-00-01811 (beilstein handbook reference)
unii-d3jc433ceb
AKOS015831346
2-amino-6-nitrotoluene
2-methyl-3-nitroaniline
nsc-227939
nsc227939
603-83-8
benzenamine, 2-methyl-3-nitro-
nsc-25011
AC-907/25014174
2-methyl-3-nitro-aniline
x-nitro-o-toluidine
NCGC00091779-01
brn 0388393
o-toluidine, 3-nitro-
3-nitro-o-toluidine
nsc 227939
einecs 210-059-6
2-methyl-3-nitroaniline, 97%
NCIOPEN2_002635
inchi=1/c7h8n2o2/c1-5-6(8)3-2-4-7(5)9(10)11/h2-4h,8h2,1h
STL069425
MLS002454365
smr001371989
N0455
1-amino-2-methyl-3-nitrobenzene
AKOS000120322
A8426
NCGC00091779-02
HMS3039H05
NCGC00258327-01
cas-603-83-8
tox21_200773
dtxcid505628
dtxsid8025628 ,
2-methyl-3-nitrobenzenamine
2-methyl-3-nitro-phenylamine
FT-0602349
AM20050227
3-(cyclohexylsulfonyl)phenylboronic acid
CS-M0044
SCHEMBL190550
PS-6293
2-methyl-3-nitro aniline
2-nitro-6-aminotoluene
2-amino-6-nitro-toluene
AKOS024268502
2-nitro-6-amino toluene
2-methy-3-nitroaniline
CHEMBL1882292
SCHEMBL15630321
mfcd00007731
F8880-4835
J-509954
(2-methyl-3-nitrophenyl)amine
P20503
EN300-20624
6-amino-2-nitrotoluene
6-nitro-2-aminotoluene
methyl-3-nitroaniline, 2-
Z104479332
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (7)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
RAR-related orphan receptor gammaMus musculus (house mouse)Potency0.24730.006038.004119,952.5996AID1159521
USP1 protein, partialHomo sapiens (human)Potency28.18380.031637.5844354.8130AID743255
AR proteinHomo sapiens (human)Potency30.55090.000221.22318,912.5098AID1259243; AID1259247
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency43.25370.001022.650876.6163AID1224838; AID1224893
aryl hydrocarbon receptorHomo sapiens (human)Potency31.13700.000723.06741,258.9301AID743122
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency7.82130.000323.4451159.6830AID743065
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency74.97800.000627.21521,122.0200AID651741
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (13)

Assay IDTitleYearJournalArticle
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID1745845Primary qHTS for Inhibitors of ATXN expression
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.74

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.74 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.82 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.74)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]