| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
chloroquine
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.. chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis. | 2.25 | 1 | 0 | aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound | anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug |
deoxynivalenol
deoxynivalenol : A trichothecene mycotoxin produced by Fusarium to which wheat, barley, maize (corn) and their products are susceptible to contamination. | 2.06 | 1 | 0 | cyclic ketone;
enone;
primary alcohol;
secondary alpha-hydroxy ketone;
trichothecene;
triol | mycotoxin |
moniliformin
moniliformin: RN given refers to parent cpd; structure; do not confuse with plant product, moniliformin | 2.48 | 2 | 0 | | |
aurofusarin
aurofusarin: from Fusarium graminearum; structure given in first source | 2.08 | 1 | 0 | organic heterotricyclic compound;
organooxygen compound | |
enniatin b
enniatins: cyclohexadepsipeptides containing valine, isoleucine & valeric acid from Fusarian; form complexes with cations & cellular membranes; there are at least three different enniatins H, B & C; minor descriptor (76-86); on-line & INDEX MEDICUS search PEPTIDES, CYCLIC (76-86); see also record for enniatin D, E, F. enniatin B : An enniatin obtained from formal cyclocondensation of three N-[(2R)-2-hydroxy-3-methylbutanoyl]-N-methyl-L-valine units. | 2.48 | 2 | 0 | enniatin | antimicrobial agent |
15-acetoxyscirpen-3,4-diol
15-acetoxyscirpen-3,4-diol: hydrolysis product of anguidine | 2.06 | 1 | 0 | trichothecene | |
nivalenol
nivalenol: RN given refers to 3alpha,4beta,7alpha-isomer | 2.06 | 1 | 0 | trichothecene | |
ergosterol
[no description available] | 2.08 | 1 | 0 | 3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols | fungal metabolite;
Saccharomyces cerevisiae metabolite |
naphthoquinones
Naphthoquinones: Naphthalene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups. | 2.08 | 1 | 0 | | |
fusarin c
fusarin C: structure given in first source | 2.08 | 1 | 0 | sesquiterpenoid | |
concanamycin a
concanamycin A: from Streptomyces diastatochromogenes S-45; inhibits vacuolar H+ ATPase. concanamycin A : A concanamycin in which the lactone ring contains 4 double bonds and is substituted by 4 methyl groups, 2 hydroxy groups, 2 methoxy groups and an ethyl group. | 2.25 | 1 | 0 | carbamate ester;
concanamycin | antifungal agent;
EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor;
metabolite |
chlamydosporal
chlamydosporal: new metabolite from Fusarium chlamydosporum; structure given in first source | 2.08 | 1 | 0 | | |