Compounds > 2-acetylaminofluorene-n-sulfate
Page last updated: 2024-12-06

2-acetylaminofluorene-n-sulfate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2-acetylaminofluorene-N-sulfate: reactive intermediate of 2-acetylaminofluorene; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID28091
CHEBI ID35424
MeSH IDM0136031

Synonyms (22)

Synonym
acetohydroxamic acid, n-fluoren-2-yl-, sulfate ester
hydroxylamine-o-sulfonic acid, n-acetyl-n-(2-fluorenyl)-
n-sulfonoxy-n-acetyl-2-aminofluorene
n-fluoren-2-ylacetohydroxamic acid sulfate
n-sulfonoxy-aaf
acetamide, n-9h-fluoren-2-yl-n-(sulfooxy)-
acetylaminofluorene-n-sulfate
sulfate ester of n-hydroxy-n-2-fluorenylacetamide
2-acetylaminofluorene-n-sulfate
n-(9h-fluoren-2-yl)-n-acetylhydroxylamine-o-sulfonic acid
16808-85-8
2-acetylaminofluorene n-sulfate
n-(sulfoxy)-2-fluorenylacetamide
n-(9h-fluoren-2-yl)-n-(sulfooxy)acetamide
CHEBI:35424
n-sulfonyloxy-2-acetylaminofluorene
2-acetamidofluorene n-sulfate
[acetyl(9h-fluoren-2-yl)amino] hydrogen sulfate
n-sulfooxy-2-acetylaminofluorene
n-(sulfooxy)-2-fluorenylacetamide
DTXSID80168475
Q27116473
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
hydroxylamine O-sulfonic acid
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (4)

PathwayProteinsCompounds
Metabolism14961108
Biological oxidations150276
Phase II - Conjugation of compounds73122
Cytosolic sulfonation of small molecules1747

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.37

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.37 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.37)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
sulfuric acid
sulfuric acid : A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom.		1.9710sulfur oxoacidcatalyst
potassium chloride
Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.. potassium chloride : A metal chloride salt with a K(+) counterion.		1.9610inorganic chloride;
inorganic potassium salt;
potassium salt		fertilizer
hydroxyacetylaminofluorene
Hydroxyacetylaminofluorene: A N-hydroxylated derivative of 2-ACETYLAMINOFLUORENE that has demonstrated carcinogenic action.		2.88402-acetamidofluorenes
2-acetylaminofluorene
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.		8.06502-acetamidofluorenesantimitotic;
carcinogenic agent;
epitope;
mutagen
methionine
Methionine: A sulfur-containing essential L-amino acid that is important in many body functions.. methionine : A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4.		1.9610aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
acetoxyacetylaminofluorene
Acetoxyacetylaminofluorene: An alkylating agent that forms DNA ADDUCTS at the C-8 position in GUANINE, resulting in single strand breaks. It has demonstrated carcinogenic action.. N-acetoxy-2-acetamidofluorene : A 2-acetamidofluorene compound in which the parent 2-acetamidofluorene is substituted on nitrogen by an acetoxy group.		1.96102-acetamidofluorenescarcinogenic agent;
mutagen
n-acetylmethionine
N-acetylmethionine: RN given refers to L-isomer. N-acetylmethionine : A methionine derivative that is methionine in which one of the amine hydrogens is substituted by an acetyl group.		1.9610L-methionine derivative;
N-acetyl-L-amino acid;
N-acetylmethionine		nutraceutical
cysteine
Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3.		1.9610cysteiniumfundamental metabolite
guanosine
ribonucleoside : Any nucleoside where the sugar component is D-ribose.		1.9610guanosines;
purines D-ribonucleoside		fundamental metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Experimental Hepatoma
[description not available]		01.9710