Page last updated: 2024-12-08

2,5-dihydrophenylalanine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2,5-dihydrophenylalanine: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID441444
CHEMBL ID3251934
CHEBI ID27940
SCHEMBL ID3917899
MeSH IDM0045148

Synonyms (22)

Synonym
antibiotic u 51738
alanine, 3-(2,5-cyclohexadienyl)-, l-
1,4-cyclohexadiene-1-propionic acid, alpha-amino-, l-
CHEBI:27940 ,
l-3-(2,5-cyclohexadienyl)alanine
2,5-dihydrophenyl-l-alanine
(2s)-2-amino-3-(cyclohexa-1,4-dien-1-yl)propanoic acid
3-(cyclohexa-1,4-dien-1-yl)-l-alanine
(s)-alpha-amino-1,4-cyclohexadiene-1-propanoic acid
16055-12-2
C08273
2,5-dihydrophenylalanine
l-2,5-dihydrophenylalanine
(2s)-2-amino-3-cyclohexa-1,4-dien-1-ylpropanoic acid
3-(1,4-cyclohexadienyl)-l-alanine
CHEMBL3251934
SCHEMBL3917899
FSZMHEMPLAVBQZ-QMMMGPOBSA-N
2,5-dihydro-l-phenylalanine
Q27103413
(alphas)-alpha-amino-1,4-cyclohexadiene-1-propanoic acid
DTXSID001235696
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
non-proteinogenic L-alpha-amino acidAny L-alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID1131307Stability of the compound in phosphate buffer at pH 7.5 in presence of rat kidney homogenates1979Journal of medicinal chemistry, Dec, Volume: 22, Issue:12
[3-(1,4-Cyclohexadienyl)-L-alanine,8-lysine]vasopressin: synthesis and some pharmacological properties.
AID1266381Competitive inhibition of rabbit small intestine IDO1 by double reciprocal plot analysis in presence of L-tryptophan2015Journal of medicinal chemistry, Dec-24, Volume: 58, Issue:24
Challenges in the Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors.
AID1131308Stability of the compound in phosphate buffer at pH 7.5 in presence of rat liver homogenates1979Journal of medicinal chemistry, Dec, Volume: 22, Issue:12
[3-(1,4-Cyclohexadienyl)-L-alanine,8-lysine]vasopressin: synthesis and some pharmacological properties.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.58

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.58 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.97 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.58)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (10.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (90.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]