Page last updated: 2024-12-07
2,4-dinitroimidazole-1-ethanol
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
2,4-dinitroimidazole-1-ethanol: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 125775 |
| CHEMBL ID | 350013 |
| SCHEMBL ID | 3303223 |
| MeSH ID | M0073637 |
Synonyms (10)
| Synonym |
|---|
| ka 161 |
| 2-(2,4-dinitroimidazol-1-yl)ethanol |
| CHEMBL350013 |
| 69542-89-8 |
| 1h-imidazole-1-ethanol, 2,4-dinitro- |
| 2,4-dinitroimidazole-1-ethanol |
| ka-161 |
| SCHEMBL3303223 |
| DTXSID00989523 |
| 2-(2,4-dinitro-1h-imidazol-1-yl)ethan-1-ol |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (5)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID229115 | Radiosensitizing effectivity evaluated as its ability to sensitize hypoxic Chinese hamster cells (V-79) towards ionizing radiation at 0.1 mM | 1981 | Journal of medicinal chemistry, May, Volume: 24, Issue:5 | Potential radiosensitizing agents. 2. Synthesis and biological activity of derivatives of dinitroimidazole with oxiranes. |
| AID1123542 | Induction of sensitization to irradiation in Escherichia coli AB1157 under hypoxic condition assessed as reduction in colony formation at 1 mM measured after irradiation | 1979 | Journal of medicinal chemistry, May, Volume: 22, Issue:5 | Potential radiosensitizing agents. Dinitroimidazoles. |
| AID1123544 | Induction of sensitization to irradiation in Escherichia coli AB1157 under oxic condition assessed as reduction in colony formation at 1 mM measured after irradiation | 1979 | Journal of medicinal chemistry, May, Volume: 22, Issue:5 | Potential radiosensitizing agents. Dinitroimidazoles. |
| AID1123543 | Antimicrobial activity against Escherichia coli AB1157 assessed as reduction in colony formation at 1 mM | 1979 | Journal of medicinal chemistry, May, Volume: 22, Issue:5 | Potential radiosensitizing agents. Dinitroimidazoles. |
| AID84701 | Concentration needed to achieve 50% kill of chinese hamster cells under oxygenated conditions on exposure for 2 hours | 1981 | Journal of medicinal chemistry, May, Volume: 24, Issue:5 | Potential radiosensitizing agents. 2. Synthesis and biological activity of derivatives of dinitroimidazole with oxiranes. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (8)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 8 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.25
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.25) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||