Compounds > 2,4-dichlorophenoxyacetic acid methyl ester
Page last updated: 2024-11-04

2,4-dichlorophenoxyacetic acid methyl ester

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID1488
CHEMBL ID1327631
SCHEMBL ID5004223
MeSH IDM0190715

Synonyms (82)

Synonym
KBIO1_001512
DIVK1C_006568
ai3-14625
2,4-dichlorophenoxyacetic acid, methyl ester
epa pesticide chemical code 030067
2,4-d-methyl [iso]
brn 2053392
einecs 217-670-7
caswell no. 315aw
ccris 1458
2,4-d-methyl
methyl 2,4-dichlorophenoxyacetate
nsc 9399
SPECTRUM_001861
acetic acid,4-dichlorophenoxy)-, methyl ester
2,4-d methyl ester
methyl (2,4-dichlorophenoxy)acetate
1928-38-7
nsc9399
methyl 2,4-d ester
nsc-9399
(2, methyl ester
2,4-dichlorophenoxyacetic acid methyl ester
acetic acid, (2,4-dichlorophenoxy)-, methyl ester
SPECTRUM5_001986
BSPBIO_002391
2,4-d methyl ester, analytical standard
NCGC00094534-02
NCGC00094534-01
KBIOGR_001111
KBIOSS_002378
KBIO2_007510
KBIO2_004942
KBIO2_002374
KBIO3_001891
SPECTRUM3_000836
SPBIO_001662
SPECTRUM2_001851
SPECPLUS_000472
SPECTRUM4_000676
SPECTRUM330044
NCGC00094534-03
AKOS001581160
methyl 2-(2,4-dichlorophenoxy)acetate
sg8721q1o5 ,
unii-sg8721q1o5
cas-1928-38-7
tox21_301422
NCGC00255411-01
dtxsid6041349 ,
dtxcid4021349
CCG-39389
FT-0633918
CHEMBL1327631
(2,4-dichlorophenoxy)acetic acid methyl ester
acetic acid, 2-(2,4-dichlorophenoxy)-, methyl ester
2,4-d, methyl ester
SCHEMBL5004223
2,4-d-methyl ester
STL426119
BBL034670
(2,4-dichlorophenoxy)acetic acid, methyl ester
methyl ester of 2,4-dichlorophenoxyacetic acid
(2,4-dichlorophenoxy) acetic acid, methyl ester
HWIGZMADSFQMOI-UHFFFAOYSA-N
J-521802
methyl 2-(2,4-dichlorophenoxy)-acetate
F0850-6568
sr-01000596974
SR-01000596974-1
mfcd00018356
2,4-d methyl ester, pestanal(r), analytical standard
J-012479
2,4-d-methylester
VS-12633
methyl 2,4-dichloro phenoxyethanoate
Q22329230
methyl2-(2,4-dichlorophenoxy)acetate
CS-0086889
F87217
2,4-dichlorophenoxy acetic acid-methyl ester
EN300-1266013
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (6)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, Ferritin light chainEquus caballus (horse)Potency50.11875.623417.292931.6228AID485281
LuciferasePhotinus pyralis (common eastern firefly)Potency44.78530.007215.758889.3584AID1224835
SMAD family member 2Homo sapiens (human)Potency30.89560.173734.304761.8120AID1346859
SMAD family member 3Homo sapiens (human)Potency30.89560.173734.304761.8120AID1346859
GLI family zinc finger 3Homo sapiens (human)Potency10.87070.000714.592883.7951AID1259369
thyroid stimulating hormone receptorHomo sapiens (human)Potency34.37620.001628.015177.1139AID1224843
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (4)

Assay IDTitleYearJournalArticle
AID977602Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID977599Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID1159550Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening2015Nature cell biology, Nov, Volume: 17, Issue:11
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 13.13

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index13.13 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.92 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (13.13)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (20.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
2,4-dichlorophenoxyacetic acid
2,4-Dichlorophenoxyacetic Acid: An herbicide with irritant effects on the eye and the gastrointestinal system.. 2,4-D : A chlorophenoxyacetic acid that is phenoxyacetic acid in which the ring hydrogens at postions 2 and 4 are substituted by chlorines.		2.420chlorophenoxyacetic acid;
dichlorobenzene		agrochemical;
defoliant;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
environmental contaminant;
phenoxy herbicide;
synthetic auxin
simazine
Simazine: A triazine herbicide.. simazine : A diamino-1,3,5-triazine that is N,N'-diethyl-1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6.		2.0110chloro-1,3,5-triazine;
diamino-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
ConditionIndicatedRelationship StrengthStudiesTrials
Benign Neoplasms
[description not available]		03.0310
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.		03.0310
Anemia, Fanconi
[description not available]		02.1310
Fanconi Anemia
Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)		02.1310