Compounds > 2,3-n-octanoylsphingosine
Page last updated: 2024-08-01 21:11:36

2,3-n-octanoylsphingosine

Description

N-octanoylsphingosine : An N-acylsphingosine in which the ceramide N-acyl group is specified as octanoyl. [CHeBI]

Cross-References

ID SourceID
PubMed CID5702614
CHEMBL ID444463
SCHEMBL ID14020687
CHEBI ID45815
MeSH IDM0181508

Synonyms (42)

Synonym
IDI1_034039
BSPBIO_001569
NCGC00161360-01
NCGC00161360-02
c8 ceramide
NCGC00161360-03
HMS1989O11
n-octanoyl-d-erythro-sphingosine
74713-59-0
BML3-D01
HMS1361O11
HMS1791O11
n-[(e,2s,3r)-1,3-dihydroxyoctadec-4-en-2-yl]octanamide
chebi:45815 ,
n-octanoylsphingosine
CHEMBL444463
c8-ceramide
c-8 ceramide
n-[(2s,3r,4e)-1,3-dihydroxyoctadec-4-en-2-yl]octanamide
n-octanoyl sphingosine
cer(d18:1/8:0)
n-octanoylsphing-4-enine
SCHEMBL14020687
APDLCSPGWPLYEQ-WRBRXSDHSA-N
HMS3649E13
HMS3402O11
n-octanoylsphingosine,d-erythro
c8 ceramide (d18:1/8:0), n-octanoyl-d-erythro-sphingosine, powder
n-((2s,3r,e)-1,3-dihydroxyoctadec-4-en-2-yl)octanamide
mfcd00236496
EX-A1429
Q27120632
sr-01000946565
SR-01000946565-1
ceramide 8; d-erythro-n-octanoylsphingosine; n-octanoyl-c18-sphingosine
AS-56387
AKOS037645042
n-[(1s,2r,3e)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-octanamide
HY-108391
DTXSID701318293
CS-0028558
BP-28810

Drug Classes (1)

ClassDescription
N-acylsphingosineThe parent compounds of the ceramide family, composed of sphingosine having an unspecified fatty acyl group attached to the nitrogen.

Protein Targets (2)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
phosphopantetheinyl transferaseBacillus subtilisPotency89.1251AID1490
glucocerebrosidaseHomo sapiens (human)Potency25.1189AID2101

Bioassays (30)

Assay IDTitleYearJournalArticle
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
ISSN: 1872-9096		High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
AID1347154Primary screen GU AMC qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
ISSN: 1091-6490		Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1508630Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay2021Cell reports, 04-27, Volume: 35, Issue:4
ISSN: 2211-1247		A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
AID431777Selectivity for tumor necrosis factor-resistant human MCF7 cells over human MCF10A cells2009Journal of medicinal chemistry, Sep-24, Volume: 52, Issue:18
ISSN: 1520-4804		Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells.
AID401377Toxicity against Ulva conglobata at 50 ppm1998Journal of natural products, Jun-26, Volume: 61, Issue:6
ISSN: 0163-3864		New ceramide from marine sponge Haliclona koremella and related compounds as antifouling substances against macroalgae.
AID431784Increase in endogenous sphingosine-1-phosphate level in tumor necrosis factor-resistant human MCF7 cells at 10 uM after by ESI/MS/MS analysis2009Journal of medicinal chemistry, Sep-24, Volume: 52, Issue:18
ISSN: 1520-4804		Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells.
AID547622Antitrypanosomal activity against Trypanosoma cruzi amastigotes infected in BESM cells measured after 88 hrs postinfection by HTS assay2010Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8
ISSN: 1098-6596		Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease.
AID654948Potentiation of etoposide-induced antiproliferative activity against human MCF-7TN-R cells after 24 hrs by MTT assay2012Bioorganic & medicinal chemistry letters, Apr-01, Volume: 22, Issue:7
ISSN: 1464-3405		Anti-proliferative effects of the novel ceramide analog (S)-2-(benzylideneamino)-3-hydroxy-N-tetrade-cylpropanamide in chemoresistant cancer.
AID658812Induction of apoptosis in human HCT116 cells at 30 uM after 14 hrs by Annexin V-propidium iodide staining based flow cytometry2012Bioorganic & medicinal chemistry, May-15, Volume: 20, Issue:10
ISSN: 1464-3391		3-Deoxy-3,4-dehydro analogs of XM462. Preparation and activity on sphingolipid metabolism and cell fate.
AID431775Antiproliferative activity against tumor necrosis factor-resistant human MCF7 cells after 24 hrs by MTT assay2009Journal of medicinal chemistry, Sep-24, Volume: 52, Issue:18
ISSN: 1520-4804		Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells.
AID654837Antiproliferative activity against human MDA-MB-231 cells assessed as decrease in Ki-67 staining after 48 hrs by immunofluorescence staining2012Bioorganic & medicinal chemistry letters, Apr-01, Volume: 22, Issue:7
ISSN: 1464-3405		Anti-proliferative effects of the novel ceramide analog (S)-2-(benzylideneamino)-3-hydroxy-N-tetrade-cylpropanamide in chemoresistant cancer.
AID654838Antiproliferative activity against human MDA-MB-468 cells assessed as decrease in Ki-67 staining after 48 hrs by immunofluorescence staining2012Bioorganic & medicinal chemistry letters, Apr-01, Volume: 22, Issue:7
ISSN: 1464-3405		Anti-proliferative effects of the novel ceramide analog (S)-2-(benzylideneamino)-3-hydroxy-N-tetrade-cylpropanamide in chemoresistant cancer.
AID431769Inhibition of clonogenic survival of endocrine-resistant human MDA-MB-231 cells after 10 days by microscopy2009Journal of medicinal chemistry, Sep-24, Volume: 52, Issue:18
ISSN: 1520-4804		Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells.
AID431776Antiproliferative activity against human MCF10A cells at 100 uM after 24 hrs by MTT assay2009Journal of medicinal chemistry, Sep-24, Volume: 52, Issue:18
ISSN: 1520-4804		Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells.
AID492066Cytotoxicity against human MCF-7TN-R cells assessed as reduction in cell viability after 24 hrs by MTT assay2010Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14
ISSN: 1464-3391		Novel anti-viability ceramide analogs: design, synthesis, and structure-activity relationship studies of substituted (S)-2-(benzylideneamino)-3-hydroxy-N-tetradecylpropanamides.
AID431774Antiproliferative activity against endocrine-resistant human MDA-MB-231 cells after 24 hrs by MTT assay2009Journal of medicinal chemistry, Sep-24, Volume: 52, Issue:18
ISSN: 1520-4804		Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells.
AID547621Cytotoxicity against BESM cells after 88 hrs by HTS assay2010Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8
ISSN: 1098-6596		Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease.
AID1069719Induction of apoptosis in human MCF-7TN-R cells at 2 times IC50 determined from MTT assay after 24 hrs by ELISA relative to control2014Bioorganic & medicinal chemistry, Feb-15, Volume: 22, Issue:4
ISSN: 1464-3391		3-Ketone-4,6-diene ceramide analogs exclusively induce apoptosis in chemo-resistant cancer cells.
AID431768Inhibition of clonogenic survival of human MCF7 cells after 10 days by microscopy2009Journal of medicinal chemistry, Sep-24, Volume: 52, Issue:18
ISSN: 1520-4804		Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells.
AID431771Induction of apoptosis in human MCF7 cells assessed as appearance of nucleosomes in cytoplasm at 8.3 uM after 24 hrs by ELISA relative to DMSO control2009Journal of medicinal chemistry, Sep-24, Volume: 52, Issue:18
ISSN: 1520-4804		Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells.
AID1069717Induction of apoptosis in human MCF-7TN-R cells assessed as caspase-9 activation at 2 times IC50 determined from MTT assay after 24 hrs by caspase Glo 9 assay relative to vehicle-treated control2014Bioorganic & medicinal chemistry, Feb-15, Volume: 22, Issue:4
ISSN: 1464-3391		3-Ketone-4,6-diene ceramide analogs exclusively induce apoptosis in chemo-resistant cancer cells.
AID654949Potentiation of doxorubicin-induced antiproliferative activity against human MCF-7TN-R cells after 24 hrs by MTT assay2012Bioorganic & medicinal chemistry letters, Apr-01, Volume: 22, Issue:7
ISSN: 1464-3405		Anti-proliferative effects of the novel ceramide analog (S)-2-(benzylideneamino)-3-hydroxy-N-tetrade-cylpropanamide in chemoresistant cancer.
AID431783Increase in endogenous sphingosine-1-phosphate level in endocrine-resistant human MDA-MB-231 cells at 10 uM after by ESI/MS/MS analysis2009Journal of medicinal chemistry, Sep-24, Volume: 52, Issue:18
ISSN: 1520-4804		Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells.
AID431782Increase in endogenous sphingosine-1-phosphate level in human MCF7 cells at 10 uM after by ESI/MS/MS analysis2009Journal of medicinal chemistry, Sep-24, Volume: 52, Issue:18
ISSN: 1520-4804		Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells.
AID431770Inhibition of clonogenic survival of tumor necrosis factor-resistant human MCF7 cells after 10 days by microscopy2009Journal of medicinal chemistry, Sep-24, Volume: 52, Issue:18
ISSN: 1520-4804		Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells.
AID654950Induction of apoptosis in human MCF-7TN-R cells assessed as decrease in viable cells after 48 hrs by DAPI staining method relative to control2012Bioorganic & medicinal chemistry letters, Apr-01, Volume: 22, Issue:7
ISSN: 1464-3405		Anti-proliferative effects of the novel ceramide analog (S)-2-(benzylideneamino)-3-hydroxy-N-tetrade-cylpropanamide in chemoresistant cancer.
AID654836Antiproliferative activity against human MCF-7TN-R cells assessed as decrease in Ki-67 staining after 48 hrs by immunofluorescence staining2012Bioorganic & medicinal chemistry letters, Apr-01, Volume: 22, Issue:7
ISSN: 1464-3405		Anti-proliferative effects of the novel ceramide analog (S)-2-(benzylideneamino)-3-hydroxy-N-tetrade-cylpropanamide in chemoresistant cancer.
AID431773Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay2009Journal of medicinal chemistry, Sep-24, Volume: 52, Issue:18
ISSN: 1520-4804		Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells.
AID547804Selectivity window, ratio of EC50 for BESM cells to EC50 for Trypanosoma cruzi amastigotes infected in BESM cells2010Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8
ISSN: 1098-6596		Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease.
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
ISSN: 1464-3405		Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's1 (9.09)29.6817
2010's7 (63.64)24.3611
2020's2 (18.18)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
n-palmitoylsphingosine
0
Cer(d34:1);
N-acylsphingosine;
N-palmitoyl-sphingoid base		human blood serum metabolite;
Mycoplasma genitalium metabolite		00low000000
n-acetylsphingosine
0
N-acylsphingosine00low000000
n-caproylsphingosine
0
N-acylsphingosine00low000000
n-(7-(4-nitrobenzo-2-oxa-1,3-diazole))-6-aminocaproyl sphingosine
0
N-acylsphingosinefluorescent probe00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
tacrine
1
acridines;
aromatic amine		EC 3.1.1.7 (acetylcholinesterase) inhibitor2010201014.0low000100
amiodarone
1
1-benzofurans;
aromatic ketone;
organoiodine compound;
tertiary amino compound		cardiovascular drug2010201014.0low000100
amitriptyline
1
carbotricyclic compound;
tertiary amine		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
tropomyosin-related kinase B receptor agonist;
xenobiotic		2010201014.0low000100
azelastine
1
monochlorobenzenes;
phthalazines;
tertiary amino compound		anti-allergic agent;
anti-asthmatic drug;
bronchodilator agent;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
H1-receptor antagonist;
platelet aggregation inhibitor		2010201014.0low000100
carvedilol
1
carbazoles;
secondary alcohol;
secondary amino compound		alpha-adrenergic antagonist;
antihypertensive agent;
beta-adrenergic antagonist;
cardiovascular drug;
vasodilator agent		2010201014.0low000100
clomipramine
1
dibenzoazepineanticoronaviral agent;
antidepressant;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
serotonergic antagonist;
serotonergic drug;
serotonin uptake inhibitor		2010201014.0low000100
doxazosin
1
aromatic amine;
benzodioxine;
monocarboxylic acid amide;
N-acylpiperazine;
N-arylpiperazine;
quinazolines		alpha-adrenergic antagonist;
antihyperplasia drug;
antihypertensive agent;
antineoplastic agent;
vasodilator agent		2010201014.0low000100
fluphenazine
1
N-alkylpiperazine;
organofluorine compound;
phenothiazines		anticoronaviral agent;
dopaminergic antagonist;
phenothiazine antipsychotic drug		2010201014.0low000100
fluoxetine
1
(trifluoromethyl)benzenes;
aromatic ether;
secondary amino compound		2010201014.0low000100
haloperidol
1
aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol		antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist		2010201014.0low000100
homochlorocyclizine
1
diarylmethane2010201014.0low000100
lomerizine
1
diarylmethane2010201014.0low000100
loperamide
1
monocarboxylic acid amide;
monochlorobenzenes;
piperidines;
tertiary alcohol		anticoronaviral agent;
antidiarrhoeal drug;
mu-opioid receptor agonist		2010201014.0low000100
loratadine
1
benzocycloheptapyridine;
ethyl ester;
N-acylpiperidine;
organochlorine compound;
tertiary carboxamide		anti-allergic agent;
cholinergic antagonist;
geroprotector;
H1-receptor antagonist		2010201014.0low000100
naftopidil
1
piperazines2010201014.0low000100
nefazodone
1
aromatic ether;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
triazoles		alpha-adrenergic antagonist;
analgesic;
antidepressant;
serotonergic antagonist;
serotonin uptake inhibitor		2010201014.0low000100
perphenazine
1
N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
organochlorine compound;
phenothiazines		antiemetic;
dopaminergic antagonist;
phenothiazine antipsychotic drug		2010201014.0low000100
prazosin
1
aromatic ether;
furans;
monocarboxylic acid amide;
piperazines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor		2010201014.0low000100
promazine
1
phenothiazines;
tertiary amine		antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
muscarinic antagonist;
phenothiazine antipsychotic drug;
serotonergic antagonist		2010201014.0low000100
raloxifene
1
1-benzothiophenes;
aromatic ketone;
N-oxyethylpiperidine;
phenols		bone density conservation agent;
estrogen antagonist;
estrogen receptor modulator		2010201014.0low000100
sibutramine
1
organochlorine compound;
tertiary amino compound		anti-obesity agent;
serotonin uptake inhibitor		2010201014.0low000100
imatinib
1
aromatic amine;
benzamides;
N-methylpiperazine;
pyridines;
pyrimidines		antineoplastic agent;
apoptosis inducer;
tyrosine kinase inhibitor		2010201014.0low000100
norethindrone acetate
1
3-oxo-Delta(4) steroid;
acetate ester;
terminal acetylenic compound		progestin;
synthetic oral contraceptive		2010201014.0low000100
cycloheximide
1
antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol		anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor		2010201014.0low000100
phenothiazine
1
phenothiazineferroptosis inhibitor;
plant metabolite;
radical scavenger		2010201014.0low000100
cyproterone acetate
1
20-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
chlorinated steroid;
steroid ester		androgen antagonist;
geroprotector;
progestin		2010201014.0low000100
kainic acid
1
dicarboxylic acid;
L-proline derivative;
non-proteinogenic L-alpha-amino acid;
pyrrolidinecarboxylic acid		antinematodal drug;
excitatory amino acid agonist		2010201014.0low000100
3,3',4',5-tetrachlorosalicylanilide
1
dichlorobenzene;
salicylanilides		drug allergen2010201014.0low000100
metergoline
1
carbamate ester;
ergoline alkaloid		dopamine agonist;
geroprotector;
serotonergic antagonist		2010201014.0low000100
clobetasol propionate
1
11beta-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
chlorinated steroid;
fluorinated steroid;
glucocorticoid		anti-inflammatory drug2010201014.0low000100
amitraz
1
formamidines;
tertiary amino compound		acaricide;
environmental contaminant;
insecticide;
xenobiotic		2010201014.0low000100
bopindolol
1
aromatic ether;
benzoate ester;
methylindole;
secondary amino compound		2010201014.0low000100
nelfinavir
1
aryl sulfide;
benzamides;
organic heterobicyclic compound;
phenols;
secondary alcohol;
tertiary amino compound		antineoplastic agent;
HIV protease inhibitor		2010201014.0low000100
dyclonine hydrochloride
1
hydrochloridetopical anaesthetic2010201014.0low000100
ergocornine
1
ergot alkaloid2010201014.0low000100
1-benzylimidazole
1
2010201014.0low000100
mephentermine
1
2-aminooctadecane-1,3-diolEC 2.7.11.13 (protein kinase C) inhibitor;
human metabolite;
mouse metabolite		1998199826.0low001000
u 74006f
1
corticosteroid hormone2010201014.0low000100
desloratadine
1
benzocycloheptapyridineanti-allergic agent;
cholinergic antagonist;
drug metabolite;
H1-receptor antagonist		2010201014.0low000100
docetaxel
1
hydrate;
secondary alpha-hydroxy ketone		antineoplastic agent2010201014.0low000100
terconazole
1
1-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine2010201014.0low000100
dihydroergocristine monomesylate
1
methanesulfonate saltalpha-adrenergic antagonist;
geroprotector;
vasodilator agent		2010201014.0low000100
sm 8668
1
2010201014.0low000100
posaconazole
1
aromatic ether;
conazole antifungal drug;
N-arylpiperazine;
organofluorine compound;
oxolanes;
triazole antifungal drug;
triazoles		trypanocidal drug2010201014.0low000100
benztropine
1
diarylmethane2010201014.0low000100
sphingosine
1
sphing-4-eninehuman metabolite;
mouse metabolite		1998199826.0low001000
mycophenolate mofetil
1
carboxylic ester;
ether;
gamma-lactone;
phenols;
tertiary amino compound		anticoronaviral agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
immunosuppressive agent;
prodrug		2010201014.0low000100
n,n-dimethylsphingenine
1
aminodiol;
sphingoid;
tertiary amino compound		EC 2.7.1.91 (sphingosine kinase) inhibitor;
metabolite		1998199826.0low001000
n-palmitoylsphingosine
1
Cer(d34:1);
N-acylsphingosine;
N-palmitoyl-sphingoid base		human blood serum metabolite;
Mycoplasma genitalium metabolite		1998199826.0low001000
vinorelbine
1
acetate ester;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound;
ring assembly;
vinca alkaloid		antineoplastic agent;
photosensitizing agent		2010201014.0low000100
furazolidone
1
2010201014.0low000100
nitrofurazone
1
2010201014.0low000100
n-acetylsphingosine
1
N-acylsphingosine1998199826.0low001000
n-caproylsphingosine
1
N-acylsphingosine1998199826.0low001000
nifurtimox
1
nitrofuran antibiotic2010201014.0low000100
nifursol
1
2010201014.0medium000100
naloxonazine
1
2010201014.0low000100
rwj 68354
1
2010201014.0high000100
mk 936
1
2010201014.0low000100
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
American Trypanosomiasis0
1
2010201014.0low000100
Breast Cancer0
3
2009201213.7medium000210
Breast Neoplasms0
3
2009201213.7medium000210
Cancer of Colon0
1
2012201212.0low000010
Cancer of Lung0
1
2012201212.0low000010
Chagas Disease0
1
2010201014.0low000100
Colonic Neoplasms0
1
2012201212.0low000010
Congenital Zika Syndrome0
1
202020204.0low000010
Disease Models, Animal0
1
202020204.0low000010
Encephalitis, Polio0
1
2011201113.0low000010
Lung Neoplasms0
1
2012201212.0low000010
Poliomyelitis0
1
2011201113.0low000010
Zika Virus Infection0
1
202020204.0low000010