Assay ID | Title | Year | Journal | Article |
AID1379654 | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay | 2017 | European journal of medicinal chemistry, Nov-10, Volume: 140 | Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers. |
AID1379651 | Cytotoxicity against human HeLa cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay | 2017 | European journal of medicinal chemistry, Nov-10, Volume: 140 | Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers. |
AID1240133 | Inhibition of GST-GLI1 (unknown origin) interaction with DNA assessed as reduction of protein-DNA complex level at 100 uM after 20 mins by electrophoretic mobility shift assay | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17
| Hedgehog inhibitors from Withania somnifera. |
AID639258 | Cytotoxicity against human SK-MEL-28 cells after 72 hrs by MTS assay | 2011 | Journal of natural products, Dec-27, Volume: 74, Issue:12
| Cytotoxic withanolide constituents of Physalis longifolia. |
AID1379657 | Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay | 2017 | European journal of medicinal chemistry, Nov-10, Volume: 140 | Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers. |
AID1240125 | Cytotoxicity against human MCF7 cells after 24 hrs by FMCA | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17
| Hedgehog inhibitors from Withania somnifera. |
AID670605 | Cytotoxicity against human A549 cells assessed as cell viability after 72 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells. |
AID1240123 | Cytotoxicity against human PANC1 cells after 24 hrs by FMCA | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17
| Hedgehog inhibitors from Withania somnifera. |
AID670608 | Cytotoxicity against african green monkey Vero cells assessed as cell viability after 48 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells. |
AID1240124 | Cytotoxicity against human DU145 cells after 24 hrs by FMCA | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17
| Hedgehog inhibitors from Withania somnifera. |
AID670606 | Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells. |
AID670609 | Cytotoxicity against african green monkey Vero cells assessed as cell viability after 72 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells. |
AID639261 | Cytotoxicity against human MCR5 cells after 72 hrs by MTS assay | 2011 | Journal of natural products, Dec-27, Volume: 74, Issue:12
| Cytotoxic withanolide constituents of Physalis longifolia. |
AID670603 | Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells. |
AID1379652 | Cytotoxicity against human A549 cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay | 2017 | European journal of medicinal chemistry, Nov-10, Volume: 140 | Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers. |
AID670604 | Cytotoxicity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells. |
AID1379650 | Cytotoxicity against human HeLa cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay | 2017 | European journal of medicinal chemistry, Nov-10, Volume: 140 | Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers. |
AID670602 | Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells. |
AID1379655 | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay | 2017 | European journal of medicinal chemistry, Nov-10, Volume: 140 | Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers. |
AID670610 | Selectivity index, ratio of IC50 for african green monkey Vero cells to IC50 for human MCF7 cells after 48 hrs | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells. |
AID1240126 | Cytotoxicity against mouse C3H10T1/2 cells after 24 hrs by FMCA | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17
| Hedgehog inhibitors from Withania somnifera. |
AID639257 | Cytotoxicity against mouse B16F10 cells after 72 hrs by MTS assay | 2011 | Journal of natural products, Dec-27, Volume: 74, Issue:12
| Cytotoxic withanolide constituents of Physalis longifolia. |
AID639259 | Cytotoxicity against human JMAR cells after 72 hrs by MTS assay | 2011 | Journal of natural products, Dec-27, Volume: 74, Issue:12
| Cytotoxic withanolide constituents of Physalis longifolia. |
AID1379656 | Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay | 2017 | European journal of medicinal chemistry, Nov-10, Volume: 140 | Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers. |
AID1379653 | Cytotoxicity against human A549 cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay | 2017 | European journal of medicinal chemistry, Nov-10, Volume: 140 | Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers. |
AID1240122 | Inhibition of hedgehog/GLI1-mediated transcriptional activity in human HaCaT cells after 12 hrs by luciferase assay | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17
| Hedgehog inhibitors from Withania somnifera. |
AID1130018 | Induction of HSP90B' (unknown origin)-mediated heat shock response expressed in human 293T cells coexpressing GFP assessed as heat shock index after overnight incubation by luciferase reporter gene assay relative to control | 2014 | Journal of medicinal chemistry, Apr-10, Volume: 57, Issue:7
| Structure-activity relationships for withanolides as inducers of the cellular heat-shock response. |
AID1130019 | Cytotoxicity against human NCI-H929 cells after 3 days by Alamar blue assay | 2014 | Journal of medicinal chemistry, Apr-10, Volume: 57, Issue:7
| Structure-activity relationships for withanolides as inducers of the cellular heat-shock response. |
AID639260 | Cytotoxicity against human MDA1986 cells after 72 hrs by MTS assay | 2011 | Journal of natural products, Dec-27, Volume: 74, Issue:12
| Cytotoxic withanolide constituents of Physalis longifolia. |
AID670607 | Cytotoxicity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |