2,3,5,2',3',5'-hexachlorobiphenyl

Description

2,3,5,2',3',5'-hexachlorobiphenyl (PCB 153) is a highly chlorinated polychlorinated biphenyl (PCB) congener. It is a persistent organic pollutant (POP) with a high lipophilicity, meaning it readily accumulates in fatty tissues of organisms. PCBs, including PCB 153, were widely used as dielectric fluids in electrical equipment, plasticizers, and flame retardants. However, their environmental persistence and toxicity led to their production and use being phased out. PCB 153, like other PCBs, is known to be an endocrine disruptor, potentially interfering with hormone function in animals and humans. It can also cause reproductive problems, developmental delays, and immune system suppression. Its persistence in the environment and potential for bioaccumulation make it a significant environmental concern. Research on PCB 153 focuses on understanding its environmental fate, bioaccumulation, toxicity, and potential health effects. Studies aim to develop remediation strategies for contaminated sites and assess the risks posed by PCB 153 exposure.'
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2,2',3,3',5,5'-hexachlorobiphenyl : A hexachlorobiphenyl that is biphenyl in which the hydrogens at the 2, 3, and 5 positions of each of the benzene rings are replaced by chlorines. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]