Compounds > 2,3,5,2',3',5'-hexachlorobiphenyl
Page last updated: 2024-12-06
2,3,5,2',3',5'-hexachlorobiphenyl
Description
2,3,5,2',3',5'-hexachlorobiphenyl (PCB 153) is a highly chlorinated polychlorinated biphenyl (PCB) congener. It is a persistent organic pollutant (POP) with a high lipophilicity, meaning it readily accumulates in fatty tissues of organisms. PCBs, including PCB 153, were widely used as dielectric fluids in electrical equipment, plasticizers, and flame retardants. However, their environmental persistence and toxicity led to their production and use being phased out. PCB 153, like other PCBs, is known to be an endocrine disruptor, potentially interfering with hormone function in animals and humans. It can also cause reproductive problems, developmental delays, and immune system suppression. Its persistence in the environment and potential for bioaccumulation make it a significant environmental concern. Research on PCB 153 focuses on understanding its environmental fate, bioaccumulation, toxicity, and potential health effects. Studies aim to develop remediation strategies for contaminated sites and assess the risks posed by PCB 153 exposure.'
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2,2',3,3',5,5'-hexachlorobiphenyl : A hexachlorobiphenyl that is biphenyl in which the hydrogens at the 2, 3, and 5 positions of each of the benzene rings are replaced by chlorines. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
ID Source | ID |
PubMed CID | 37249 |
CHEBI ID | 34197 |
SCHEMBL ID | 2930780 |
MeSH ID | M0088895 |
Synonyms (21)
Synonym |
CHEBI:34197 , |
2,3,5,2',3',5'-hexachlorobiphenyl |
2,2',3,3',5,5'-hexachloro-1,1'-biphenyl |
1,1'-biphenyl, 2,2',3,3',5,5'-hexachloro- |
35694-04-3 |
pcb 133 |
2,2',3,3',5,5'-hexachlorobiphenyl |
brn 2288106 |
1,2,5-trichloro-3-(2,3,5-trichlorophenyl)benzene |
p7eud9w45v , |
unii-p7eud9w45v |
2,2',3,3',5,5'-pcb |
biphenyl, 2,2',3,3',5,5'-hexachloro- |
1,1'-biphenyl,2,2',3,3',5,5'-hexachloro- |
SCHEMBL2930780 |
AJKLKINFZLWHQE-UHFFFAOYSA-N |
2,2',3,3',5,5'-hexachloro-1,1'-biphenyl # |
DTXSID4030045 , |
2,2,3,3,5,5-hexachlorobiphenyl |
Q27115895 |
dtxcid2010045 |
Drug Classes (2)
Class | Description |
hexachlorobiphenyl | Any polychlorobiphenyl with molecular formula C12H4Cl6. |
trichlorobenzene | Any member of the class of chlorobenzenes carrying three chloro substituents at unspecified positions. |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (5)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 5 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.66
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 12.66 (24.57) | Research Supply Index | 1.79 (2.92) | Research Growth Index | 4.45 (4.65) | Search Engine Demand Index | 0.00 (26.88) | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |