Compounds > 2,2-bis(3-chloro-4-hydroxyphenyl)propane
Page last updated: 2024-11-06

2,2-bis(3-chloro-4-hydroxyphenyl)propane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2,2-bis(3-chloro-4-hydroxyphenyl)propane: has estrogenic activity; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID66238
SCHEMBL ID37041
MeSH IDM0482150

Synonyms (40)

Synonym
ENAMINE_005935
3,3'-dichlorodian
nsc18247
4,4'-isopropylidenebis[2-chlorophenol]
2,2-bis(4-hydroxy-3-chlorophenyl)propane
79-98-1
phenol,4'-isopropylidenebis[2-chloro-
nsc-18247
3,3'-dichlorobisphenol a
phenol,4'-(1-methylethylidene)bis[2-chloro-
2,2-bis(3-chloro-4-hydroxyphenyl)propane
OPREA1_815250
nsc 18247
einecs 201-241-6
4,4'-isopropylidenebis(2-chlorophenol)
4,4'-isopropylidenebis(o-chlorophenol)
phenol, 4,4'-(1-methylethylidene)bis(2-chloro-
phenol, 4,4'-isopropylidenebis(2-chloro-
IDI1_008170
HMS1410N17
2-chloro-4-[2-(3-chloro-4-hydroxyphenyl)propan-2-yl]phenol
FT-0666557
unii-ws963ra8kz
ws963ra8kz ,
4,4'-(1-methylethylidene)bis[2-chlorophenol]
2,2-di(4-hydroxy-3-chlorophenyl)propane
phenol, 4,4'-(1-methylethylidene)bis[2-chloro-
SCHEMBL37041
2,2-bis(3-chloro,-4-hydroxyphenyl)propane
2,2-bis-(4-hydroxy-3-chlorphenyl)-propane
DTXSID3058826
4,4'-isopropylidenebis[o-chlorophenol]
4,4'-isopropylidene-bis(2-chlorophenol)
sr-01000596913
SR-01000596913-1
2,2'-dichloro bisphenol a
AS-6196
4,4'-(propane-2,2-diyl)bis(2-chlorophenol)
2,2-bis(3-chloro-4-hydroxyphenyl) propane
AKOS037645642
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (4)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.91

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.91 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.70 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.91)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
2,3,4,6-tetrachlorophenol
2,3,4,6-tetrachlorophenol: RN given refers to parent cpd; see also record for tetrachlorophenol with locants for chloro groups not specified. 2,3,4,6-tetrachlorophenol : A tetrachlorophenol in which the chlorines are located at positions 2, 3, 4, and 6.		2.0210tetrachlorophenolxenobiotic metabolite
bisphenol a
4,4'-isopropylidene diphenol: stimulates proliferative responses and cytokine productions of murine spleen cells and thymus cells in vitro. bisphenol : By usage, the methylenediphenols, HOC6H4CH2C6H4OH, commonly p,p-methylenediphenol, and their substitution products (generally derived from condensation of two equivalent amounts of a phenol with an aldehyde or ketone). The term also includes analogues in the the methylene (or substituted methylene) group has been replaced by a heteroatom.. bisphenol A : A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.		2.0210bisphenolendocrine disruptor;
environmental contaminant;
xenobiotic;
xenoestrogen
chlorine
Chlorine: An element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family.		2.0210diatomic chlorine;
gas molecular entity		bleaching agent
ConditionIndicatedRelationship StrengthStudiesTrials
Encephalitis, Polio
[description not available]		02.0610
Poliomyelitis
An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)		02.0610