Page last updated: 2024-12-06

2,2,2',4'-tetrachloroacetophenone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID75284
CHEMBL ID4283949
MeSH IDM0194101

Synonyms (29)

Synonym
2,4-dichlorophenacylidene chloride
nsc81222
2,2',4'-tetrachloroacetophenone
nsc-81222
acetophenone,2,2',4'-tetrachloro-
2274-66-0
ethanone,2-dichloro-1-(2,4-dichlorophenyl)-
2,4-dichlorophenacylidene dichloride
2,2-dichloro-1-(2,4-dichlorophenyl)ethanone
2,2,2',4'-tetrachloroacetophenone
einecs 218-890-6
acetophenone, 2,2,2',4'-tetrachloro-
nsc 81222
unii-o43mmi49ge
o43mmi49ge ,
ethanone, 2,2-dichloro-1-(2,4-dichlorophenyl)-
2,2-dichloro-1-(2,4-dichlorophenyl)ethan-1-one
FT-0609021
AKOS022939727
.alpha.,.alpha.,2',4'-tetrachloroacetophenone
DTXSID9062300
W-109766
mfcd00018859
2,2,2,4-tetrachloroacetophenone
CS-0206599
Q27285304
CHEMBL4283949
BS-25387
CAA27466
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (9)

Assay IDTitleYearJournalArticle
AID1422226Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation at 6 uM after 72 hrs by MTT assay relative to control2018Bioorganic & medicinal chemistry letters, 11-15, Volume: 28, Issue:21
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships.
AID1422221Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell proliferation at 2 uM after 72 hrs by MTT assay relative to control2018Bioorganic & medicinal chemistry letters, 11-15, Volume: 28, Issue:21
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships.
AID1422225Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation at 12 uM after 72 hrs by MTT assay relative to control2018Bioorganic & medicinal chemistry letters, 11-15, Volume: 28, Issue:21
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships.
AID1422223Antiproliferative activity against human NCI-H1650 cells assessed as inhibition of cell proliferation at 6 uM after 72 hrs by MTT assay relative to control2018Bioorganic & medicinal chemistry letters, 11-15, Volume: 28, Issue:21
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships.
AID1422220Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell proliferation at 6 uM after 72 hrs by MTT assay relative to control2018Bioorganic & medicinal chemistry letters, 11-15, Volume: 28, Issue:21
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships.
AID1422224Antiproliferative activity against human NCI-H1650 cells assessed as inhibition of cell proliferation at 2 uM after 72 hrs by MTT assay relative to control2018Bioorganic & medicinal chemistry letters, 11-15, Volume: 28, Issue:21
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships.
AID1422219Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell proliferation at 12 uM after 72 hrs by MTT assay relative to control2018Bioorganic & medicinal chemistry letters, 11-15, Volume: 28, Issue:21
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships.
AID1422222Antiproliferative activity against human NCI-H1650 cells assessed as inhibition of cell proliferation at 12 uM after 72 hrs by MTT assay relative to control2018Bioorganic & medicinal chemistry letters, 11-15, Volume: 28, Issue:21
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships.
AID1422227Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation at 2 uM after 72 hrs by MTT assay relative to control2018Bioorganic & medicinal chemistry letters, 11-15, Volume: 28, Issue:21
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's1 (8.33)24.3611
2020's9 (75.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.90

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.90 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index5.47 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.90)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (8.33%)6.00%
Case Studies2 (16.67%)4.05%
Observational0 (0.00%)0.25%
Other9 (75.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]