Page last updated: 2024-12-06

2,2'-dithiobis(n-2-hydroxypropylbenzamide)

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2,2'-dithiobis(N-2-hydroxypropylbenzamide): platelet aggregation inhibitor; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID72555
CHEMBL ID52431
SCHEMBL ID3364344
MeSH IDM0114298

Synonyms (15)

Synonym
kf-4939
2,2'-dithiobis(n-2-hydroxypropylbenzamide)
kf 4939
2,2'-dithiobis(n-(2-hydroxypropyl)benzamide)
brn 6076613
benzamide, 2,2'-dithiobis(n-(2-hydroxypropyl)-
2,2'-dithiobis[n-(2-hydroxypropyl)benzamide]
73845-37-1
n-(2-hydroxypropyl)-2-[[2-(2-hydroxypropylcarbamoyl)phenyl]disulfanyl]benzamide
CHEMBL52431
2,2'-disulfanediylbis[n-(2-hydroxypropyl)benzamide]
SCHEMBL3364344
DTXSID10994981
2,2'-disulfanediylbis[n-(2-hydroxypropyl)benzene-1-carboximidic acid]
PD161088

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" This action carried over to ex vivo situation following intraduodenal dosing as demonstrated in rabbits."( Inhibition of platelet aggregation by a new agent, 2,2'-dithiobis-(N-2-hydroxypropyl benzamide) (KF4939).
Nakamizo, N; Shuto, K; Yamada, K, 1983
)
0.27
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID144139Antibacterial activity against Mycobacterium intracellular.1985Journal of medicinal chemistry, Dec, Volume: 28, Issue:12
Synthesis and antibacterial activity of 2,2'-dithiobis(benzamide) derivatives against Mycobacterium species.
AID144146Antibacterial activity against Mycobacterium kansasii1985Journal of medicinal chemistry, Dec, Volume: 28, Issue:12
Synthesis and antibacterial activity of 2,2'-dithiobis(benzamide) derivatives against Mycobacterium species.
AID145298Antibacterial activity against Mycobacterium tuberculosis H37Rv.1985Journal of medicinal chemistry, Dec, Volume: 28, Issue:12
Synthesis and antibacterial activity of 2,2'-dithiobis(benzamide) derivatives against Mycobacterium species.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.50 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]