2,2'-diamino-1,1'-dinaphthyl

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Description

2,2'-diamino-1,1'-dinaphthyl: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	20571
SCHEMBL ID	455943
MeSH ID	M0338065

Synonyms (135)

Synonym
EU-0035118
BIDD:GT0420
(s)-(-)-1,1'-binaphthyl-2,2'-diamine
18531-95-8
(r)-(+)-1,1'-binaphthyl-2,2'-diamine
c20h16n2
(1,1'-binaphthalene)-2,2'-diamine
2,2'-diamino-1,1'-dinaphthyl
1,1'-bi(2-naphthylamine)
1,1'-bi(2-naphthalenylamine)
nsc 519704
brn 2138401
4488-22-6
wln: l66j cz b- 2
1,1'-bi[2-naphthylamine]
nsc-519704
nsc519704
1,1'-bi[2-naphthalenylamine]
1,1'-binaphthyl-2,2'-diamine, 96%
(s)-(-)-1,1'-binaphthyl-2,2'-diamine, 99%
(r)-(+)-1,1'-binaphthyl-2,2'-diamine, 99%
1-(2-aminonaphthalen-1-yl)naphthalen-2-amine
AKOS001610329
A812948
1-(2-azanylnaphthalen-1-yl)naphthalen-2-amine
1-(2-amino-1-naphthalenyl)-2-naphthalenamine
A813148
18741-85-0
(s)-(-)-2,2'-diamino-1,1'-binaphthalene
1,1-binaphy1-2,2'-diamine
[1,1'-binaphthalene]-2,2'-diamine
AKOS015999158
tl35mu1249 ,
unii-tl35mu1249
4-13-00-00489 (beilstein handbook reference)
(r)-[1,1'-binaphthalene]-2,2'-diamine
FT-0637711
FT-0637744
1,1 inverted exclamation marka-binaphthyl-2,2 inverted exclamation marka-diamine
racemic-2,2'-diamino-1,1'-binaphthyl
SCHEMBL455943
(s)-(-)-[1,1'-binaphthalene]-2,2'-diamine
binam
B3923
2,2'-diamino-1,1'-binaphthyl
1,1'-binaphthyl-2,2'-diamine
(r)-(+)-[1,1'-binaphthalene]-2,2'-diamine
(r)-(+)-2,2'-diamino-1,1'-binaphthalene
AC-11350
DS-1947
s-(-)-2,2'-diamino-1,1'-binaphthalene
AC-20456
(as)-1,1'-binaphthalene-2,2'-diamine
(+/-)-1,1'-bi(2-naphthylamine)
(s)-(-)-1,1'-binaphthalene-2,2'-diamine
(r)-(+)-1,1'-binaphthalene-2,2'-diamine
CS-W007978
DTXSID70196328
SR-01000402740-1
sr-01000402740
(r)-binam
(r)-(+)-2,2'-diamino-1,1'-binaphthyl
(s)-(-)-2,2'-diamino-1,1'-binaphthyl
mfcd00145204
(s)-(-)-2,2/'-diamino-1,1/'-binaphthalene
(r)-(+)-1,1'-bi(2-naphthylamine)
J-011888
(s)-(-)-1,1'-bi(2-naphthylamine)
J-012068
(s)-(-)-2,2-diamino-1,1-binaphthalene
(s)-2,2'-diamino-1,1'-binaphthalene
(r)-2,2'-diamino-1,1'-binaphthalene
(s)-1,1'-binaphthyl-2,2'-diamine
79082-81-8
CS-0031454
BBL103722
(r)-2,2 inverted exclamation mark -diamino-1,1 inverted exclamation mark -binaphthalene
SY011491
1,1'-binaphthalene-2,2'-diamine
STL557532
FT-0712593
1,1 inverted exclamation mark -binaphthyl-2,2 inverted exclamation mark -diamine
SY013141
SY037270
(s)-2,2 inverted exclamation mark -diamino-1,1 inverted exclamation mark -binaphthalene
n-hexadecanoyl-serinemonosodiumsalt
(r)-binaphthyldiamine
(ar)-1,1'-binaphthalene-2,2'-diamine
(1,1'-binaphthalene)-2,2'-diamine, (1s)-
(as)-2,2'-diamino-1,1'-binaphthalene
(s)-binam
(1,1'-binaphthalene)-2,2'-diamine, (s)-(-)-
(+)-2,2'-diamino-1,1'-binaphthyl
(-)-1,1'-binaphthyl-2,2'-diamine
2,2'-diamino-1,1'-dinaphthyl, (s)-
unii-7ol97nn4u4
(ar)-2,2'-diamino-1,1'-binaphthalene
(s)-2,2'-diamino-1,1'-binaphthyl
2,2'-diamino-1,1'-dinaphthyl, (r)-
7ol97nn4u4 ,
(1,1'-binaphthalene)-2,2'-diamine, (+)-
(1,1'-binaphthalene)-2,2'-diamine, (1r)-
xi03tw52ao ,
(r)-1,1'-binaphthalene-2,2'-diamine
(+)-1,1'-binaphthyl-2,2'-diamine
unii-xi03tw52ao
D3208
D3207
(r)-(+)-binam
(s)-(-)-binam
AMY19833
(r)-1,1'-binaphthyl-2,2'-diamine
OL10247
OL10248
OL10246
(s)-(-)- 2,2'-diamino-1,1'-binaphthalene
Q27290008
W16719
A851710
A851711
1-(2-aminonaphthalen-1-yl)naphthalen-2-amine;(r)-[1,1'-binaphthalene]-2,2'-diamine
(s)-1,1'-binaphthalene-2,2'-diamine
(r)-2,2'-diamino-1,1'-dinaphthyl
(1s)-[1,1'-binaphthalene]-2,2'-diamine
(1r)-[1,1'-binaphthalene]-2,2'-diamine
(s)-2,2'-diamino-1,1'-dinaphthyl
(-)-2,2'-diamino-1,1'-binaphthyl
(+/-)-2,2'-diamino-1,1'-binaphthalene
(+/-)-1,1'-binaphthyl-2,2'-diamine
(rs)-1,1'-binaphthalene-2,2'-diamine
rac-binam
(+/-)-2,2'-diamino-1,1'-binaphthyl
2,2'-diamino-1,1'-binaphthalene
HY-W007978B
HY-W007978

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (17)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	1 (5.88)	18.2507
2000's	7 (41.18)	29.6817
2010's	6 (35.29)	24.3611
2020's	3 (17.65)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.02

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.02 (24.57)
Research Supply Index	2.89 (2.92)
Research Growth Index	4.91 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.02)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (5.88%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	16 (94.12%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
urea pseudourea: clinical use; structure. isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.	3.41	1	isourea; monocarboxylic acid amide; one-carbon compound	Daphnia magna metabolite; Escherichia coli metabolite; fertilizer; flour treatment agent; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
tacrine Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.. tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.	2.08	1	acridines; aromatic amine	EC 3.1.1.7 (acetylcholinesterase) inhibitor
alprenolol Alprenolol: One of the ADRENERGIC BETA-ANTAGONISTS used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.. alprenolol : A secondary alcohol that is propan-2-ol substituted by a 2-allylphenoxy group at position 1 and an isopropylamino group at position 3. It is a beta-adrenergic antagonist used as a antihypertensive, anti-arrhythmia and a sympatholytic agent.	2.04	1	secondary alcohol; secondary amino compound	anti-arrhythmia drug; antihypertensive agent; beta-adrenergic antagonist; sympatholytic agent
lorazepam Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.	2.04	1	benzodiazepine
oxazepam Oxazepam: A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.. oxazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.	2.04	1	1,4-benzodiazepinone; organochlorine compound	anxiolytic drug; environmental contaminant; xenobiotic
oxprenolol Oxprenolol: A beta-adrenergic antagonist used in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety.	2.04	1	aromatic ether
propranolol Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.. propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.	2.04	1	naphthalenes; propanolamine; secondary amine	anti-arrhythmia drug; antihypertensive agent; anxiolytic drug; beta-adrenergic antagonist; environmental contaminant; human blood serum metabolite; vasodilator agent; xenobiotic
temazepam Temazepam: A benzodiazepine that acts as a GAMMA-AMINOBUTYRIC ACID modulator and anti-anxiety agent.	2.04	1	benzodiazepine
levodopa Levodopa: The naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE. It is used for the treatment of PARKINSONIAN DISORDERS and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system.. L-dopa : An optically active form of dopa having L-configuration. Used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease	2.02	1	amino acid zwitterion; dopa; L-tyrosine derivative; non-proteinogenic L-alpha-amino acid	allelochemical; antidyskinesia agent; antiparkinson drug; dopaminergic agent; hapten; human metabolite; mouse metabolite; neurotoxin; plant growth retardant; plant metabolite; prodrug
leucine Leucine: An essential branched-chain amino acid important for hemoglobin formation.. leucine : A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group.	2.05	1	amino acid zwitterion; L-alpha-amino acid; leucine; proteinogenic amino acid; pyruvate family amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
trifluoroethanol Trifluoroethanol: A non-aqueous co-solvent that serves as tool to study protein folding. It is also used in various pharmaceutical, chemical and engineering applications.	2.03	1	fluoroalcohol
2-naphthylamine 2-Naphthylamine: A naphthalene derivative with carcinogenic action.. 2-naphthylamine : A naphthylamine carrying the amino group at position 2.	2.05	1	naphthylamine	carcinogenic agent
ethylene dimethacrylate ethylene glycol dimethacrylate : The enoate ester that is the 1,2-bis(methacryloyl) derivative of ethylene glycol.	2.11	1	enoate ester	allergen; cross-linking reagent; polymerisation monomer
methylphenyl carbinol 1-phenylethanol : An aromatic alcohol that is ethanol substituted by a phenyl group at position 1.. methylbenzyl alcohol : Members of the class of benzyl alcohols substituted by at least one methyl group.	2.11	1	aromatic alcohol	mouse metabolite
acetophenone acetophenone : A methyl ketone that is acetone in which one of the methyl groups has been replaced by a phenyl group.	2.11	1	acetophenones	animal metabolite; photosensitizing agent; xenobiotic
tetrahydrofuran oxolane : A cyclic ether that is butane in which one hydrogen from each methyl group is substituted by an oxygen.	2	1	cyclic ether; oxolanes; saturated organic heteromonocyclic parent; volatile organic compound	polar aprotic solvent
2-naphthol 2-naphthol: RN given refers to parent cpd. 2-naphthol : A naphthol carrying a hydroxy group at position 2.. naphthols : Any hydroxynaphthalene derivative that has a single hydroxy substituent.	2.73	3	naphthol	antinematodal drug; genotoxin; human urinary metabolite; human xenobiotic metabolite; mouse metabolite; radical scavenger
hydrazine diamine : Any polyamine that contains two amino groups.	2.08	1	azane; hydrazines	EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
(s)-binol (1,1'-binaphthalene)-2,2'-diol: structure in first source	2.44	2	naphthols
1,1'-binaphthyl 1,1'-binaphthyl: structure in first source	2.05	1
pyridine-2-carboxaldehyde pyridine-2-carboxaldehyde: structure in first source. 2-formylpyridine : A pyridinecarbaldehyde that is pyridine in which the hydrogen at position 2 is replaced by a formyl group.	2.02	1	pyridinecarbaldehyde
palladium Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46.	2	1	metal allergen; nickel group element atom; platinum group metal atom
ruthenium Ruthenium: A hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44, and atomic weight 101.07. It is used as a catalyst and hardener for PLATINUM and PALLADIUM.	2.11	1	iron group element atom; platinum group metal atom
yttrium Yttrium: An element of the rare earth family of metals. It has the atomic symbol Y, atomic number 39, and atomic weight 88.91. In conjunction with other rare earths, yttrium is used as a phosphor in television receivers and is a component of the yttrium-aluminum garnet (YAG) lasers.	2.06	1	d-block element atom; rare earth metal atom; scandium group element atom
fluorine Fluorine: A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as fluoride (FLUORIDES) to prevent dental caries.	3.41	1	diatomic fluorine; gas molecular entity	NMR chemical shift reference compound
fluorides [no description available]	3.41	1	halide anion; monoatomic fluorine
pyrrolidine [no description available]	2.06	1	azacycloalkane; pyrrolidines; saturated organic heteromonocyclic parent
alkenes [no description available]	2.06	1
1,5-cod 1,5-cyclooctadiene: used in production of Nylon	2.11	1
1,1'-binaphthyl-2,2'-diyl hydrogen phosphate 1,1'-binaphthyl-2,2'-diyl hydrogen phosphate: structure in first source	2.04	1
2,2,2-trifluoro-1-(9-anthryl)ethanol 2,2,2-trifluoro-1-(9-anthryl)ethanol: structure in first source	2.03	1
cyanates Cyanates: Organic salts of cyanic acid containing the -OCN radical.. cyanates : Salts and esters of cyanic acid, HOC#N; compounds carrying the cyanate functional group -O-C#N.. isocyanates : Organonitrogen compounds that are derivatives of isocyanic acid; compounds containing the isocyanate functional group -N=C=O (as opposed to the cyanate group, -O-C#N).	3.41	1
prolinamide prolinamide: RN given refers to cpd without isomeric designation. L-prolinamide : The carboxamide derivative of L-proline.	2.08	1	amino acid amide; L-proline derivative; pyrrolidinecarboxamide
proline Proline: A non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons.. proline : An alpha-amino acid that is pyrrolidine bearing a carboxy substituent at position 2.	2.08	1	amino acid zwitterion; glutamine family amino acid; L-alpha-amino acid; proline; proteinogenic amino acid	algal metabolite; compatible osmolytes; Escherichia coli metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite

Condition	Relationship Strength	Studies
Bile Duct Cancer [description not available]	2	1
Breast Cancer [description not available]	2	1
Cancer of Liver [description not available]	2	1
Benign Neoplasms [description not available]	2	1
EHS Tumor [description not available]	2	1
Bile Duct Neoplasms Tumors or cancer of the BILE DUCTS.	2	1
Breast Neoplasms Tumors or cancer of the human BREAST.	2	1
Liver Neoplasms Tumors or cancer of the LIVER.	2	1
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	2	1
Cancer of Lung [description not available]	2.25	1
Lung Neoplasms Tumors or cancer of the LUNG.	2.25	1

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