Compounds > 2'-deoxyinosine triphosphate
Page last updated: 2024-10-15

2'-deoxyinosine triphosphate

Description

2'-deoxyinosine triphosphate: can be used an an alternative for dGTP [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID135398616
CHEBI ID28807
SCHEMBL ID245486
MeSH IDM0179752

Synonyms (27)

Synonym
DITP ,
C01345
deoxyinosine triphosphate
2'-deoxyinosine-5'-triphosphate
2'-deoxyinosine 5'-triphosphate
deoxyinosine 5'-triphosphate
2'-deoxyinosine 5'-(tetrahydrogen triphosphate)
CHEBI:28807
[hydroxy-[[(2r,3s,5r)-3-hydroxy-5-(6-oxo-3h-purin-9-yl)oxolan-2-yl]methoxy]phosphoryl] phosphono hydrogen phosphate
16595-02-1
inosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-
2'-ditp
2'-deoxyinosine triphosphate
SCHEMBL245486
UFJPAQSLHAGEBL-RRKCRQDMSA-N
(((2r,3s,5r)-3-hydroxy-5-(6-hydroxy-9h-purin-9-yl)tetrahydrofuran-2-yl)methyl)triphosphoric acid
AKOS024464700
DTXSID10168049
{[hydroxy({[hydroxy({[(2r,3s,5r)-3-hydroxy-5-(6-oxo-6,9-dihydro-3h-purin-9-yl)oxolan-2-yl]methoxy})phosphoryl]oxy})phosphoryl]oxy}phosphonic acid
2'-deoxy-inosine 5'-(tetrahydrogen triphosphate)
{[hydroxy({[hydroxy({[(2r,3s,5r)-3-hydroxy-5-(6-hydroxy-9h-purin-9-yl)oxolan-2-yl]methoxy})phosphoryl]oxy})phosphoryl]oxy}phosphonic acid
Q27103909
[hydroxy-[[(2r,3s,5r)-3-hydroxy-5-(6-oxo-1h-purin-9-yl)oxolan-2-yl]methoxy]phosphoryl] phosphono hydrogen phosphate
A882355
[hydroxy-[hydroxy-[[(2r,3s,5r)-3-hydroxy-5-(6-oxo-3h-purin-9-yl)oxolan-2-yl]methoxy]phosphoryl]oxy-p
(((2r,3s,5r)-3-hydroxy-5-(6-hydroxy-9h-purin-9-yl)tetrahydrofuran-2-yl)methyl)triphosphoricacid
y43 ,
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
Escherichia coli metaboliteAny bacterial metabolite produced during a metabolic reaction in Escherichia coli.
mouse metaboliteAny mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
deoxyinosine phosphate
purine 2'-deoxyribonucleoside 5'-triphosphate
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (3)

PathwayProteinsCompounds
Purine nucleotides and Nucleosides metabolism ( Purine nucleotides and Nucleosides metabolism )10577
ATP + dIDP = ADP + dITP ( Purine nucleotides and Nucleosides metabolism )74
Renz2020 - GEM of Human alveolar macrophage with SARS-CoV-20490

Research

Studies (14)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (7.14)18.7374
1990's5 (35.71)18.2507
2000's3 (21.43)29.6817
2010's4 (28.57)24.3611
2020's1 (7.14)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (7.14%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (92.86%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
kanamycin a
Kanamycin: Antibiotic complex produced by Streptomyces kanamyceticus from Japanese soil. Comprises 3 components: kanamycin A, the major component, and kanamycins B and C, the minor components.. kanamycin : Kanamycin is a naturally occurring antibiotic complex from Streptomyces kanamyceticus that consists of several components: kanamycin A, the major component (also usually designated as kanamycin), and kanamycins B, C, D and X the minor components.		2.0810kanamycinsbacterial metabolite
2'-deoxyadenosine triphosphate
2'-deoxyadenosine triphosphate: RN given refers to unlabeled parent cpd		1.98102'-deoxyadenosine 5'-phosphate;
purine 2'-deoxyribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite
2'-deoxyxanthosine
[no description available]		2.0210purines 2'-deoxy-D-ribonucleoside
xanthosine 5'-triphosphate
xanthosine 5'-triphosphate: RN given refers to parent cpd		2.0110purine ribonucleoside 5'-triphosphate;
xanthosine 5'-phosphate		Escherichia coli metabolite;
mouse metabolite
deoxyguanosine triphosphate
[no description available]		2.4320deoxyguanosine phosphate;
guanyl deoxyribonucleotide;
purine 2'-deoxyribonucleoside 5'-triphosphate		Arabidopsis thaliana metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
inosine triphosphate
Inosine Triphosphate: Inosine 5'-(tetrahydrogen triphosphate). An inosine nucleotide containing three phosphate groups esterified to the sugar moiety. Synonym: IRPPP.		5.12140inosine phosphate;
purine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
inosine diphosphate
Inosine Diphosphate: An inosine nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.		2.0510inosine phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite
2'-deoxy-7-deazaguanosine triphosphate
2'-deoxy-7-deazaguanosine triphosphate: has been proposed as a replacement for dGTP		2.6730
ConditionIndicatedRelationship StrengthStudiesTrials
Chromosomal Instability
An increased tendency to acquire CHROMOSOME ABERRATIONS when various processes involved in chromosome replication, repair, or segregation are dysfunctional.		02.0510