Page last updated: 2024-10-15

2'-deoxyguanosine 3',5'-diphosphate

Description

2'-deoxyguanosine 3',5'-diphosphate: a zinc ion chelating agent [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID135419396
CHEMBL ID1235266
SCHEMBL ID5709934
SCHEMBL ID20266288
MeSH IDM0179531

Synonyms (13)

Synonym
CHEMBL1235266
16174-59-7
2'-deoxyguanosine 3',5'-bis(dihydrogen phosphate)
[(2r,3s,5r)-5-(2-amino-6-oxo-3h-purin-9-yl)-2-(phosphonooxymethyl)oxolan-3-yl] dihydrogen phosphate
2'-deoxyguanosine 3',5'-diphosphate
3',5'-dgdp
SCHEMBL5709934
DTXSID60167229
2'-deoxyguanosine-3',5'-diphosphate
2/'-deoxyguanosine 3/',5/'-diphosphate
Q27464411
SCHEMBL20266288
[(2r,3s,5r)-5-(2-amino-6-oxo-1h-purin-9-yl)-2-(phosphonooxymethyl)oxolan-3-yl] dihydrogen phosphate
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (1)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
P2Y purinoceptor 1Meleagris gallopavo (turkey)IC50 (µMol)14.90004.19006.04258.4600AID150475
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID150478In vitro agonist activity at P2Y1 receptor in turkey erythrocyte membranes; No effect at 100 uM.1999Journal of medicinal chemistry, May-06, Volume: 42, Issue:9
Structure-activity relationships of bisphosphate nucleotide derivatives as P2Y1 receptor antagonists and partial agonists.
AID150479Antagonist activity for inhibition of PLC elicited by 10 nM 2-MeSADP at P2Y purinoceptor 1 in turkey erythrocyte membranes1999Journal of medicinal chemistry, May-06, Volume: 42, Issue:9
Structure-activity relationships of bisphosphate nucleotide derivatives as P2Y1 receptor antagonists and partial agonists.
AID150475In vitro antagonist activity at P2Y1 receptor in turkey erythrocyte membranes.1999Journal of medicinal chemistry, May-06, Volume: 42, Issue:9
Structure-activity relationships of bisphosphate nucleotide derivatives as P2Y1 receptor antagonists and partial agonists.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (11.11)18.7374
1990's4 (44.44)18.2507
2000's2 (22.22)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]