Compounds > 2',4',6'-tris(methoxymethoxy) chalcone
Page last updated: 2024-11-12

2',4',6'-tris(methoxymethoxy) chalcone

Description

2',4',6'-tris(methoxymethoxy) chalcone: structure in first souce [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID11646756
CHEMBL ID4569822
SCHEMBL ID16751995
MeSH IDM0498436

Synonyms (8)

Synonym
SCHEMBL16751995
2',4',6'-tris(methoxymethoxy) chalcone
8o4guf7mhz ,
2-propen-1-one, 3-phenyl-1-(2,4,6-tris(methoxymethoxy)phenyl)-
(2e)-3-phenyl-1-(2,4,6-tris(methoxymethoxy)phenyl)-2-propen-1-one
unii-8o4guf7mhz
884317-95-7
CHEMBL4569822
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (49)

Assay IDTitleYearJournalArticle
AID1537694Cytotoxicity against human MIAPaCa2 cells assessed as combinational index at 2.5 uM incubated for 72 hrs in presence of 200 uM 6TP by alamar blue assay2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1537691Cytotoxicity against human MIAPaCa2 cells assessed as combinational index at 2.5 uM incubated for 72 hrs in presence of 25 uM 6TP by alamar blue assay2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1537693Cytotoxicity against human MIAPaCa2 cells assessed as combinational index at 2.5 uM incubated for 72 hrs in presence of 100 uM 6TP by alamar blue assay2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1537677Cytotoxicity against human MIAPaCa2 cells assessed as cell viability at 2.5 uM incubated for 72 hrs in presence of 50 uM 6TP by alamar blue assay (Rvb = 13.8 %)2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1575598Antiproliferative activity against human U937 cells assessed as reduction in cell viability after 72 hrs by alamar blue assay2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1575595Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by alamar blue assay2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1575599Antiproliferative activity against human REH cells assessed as reduction in cell viability after 72 hrs by alamar blue assay2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1537680Cytotoxicity against human MIAPaCa2 cells assessed as cell viability at 5 uM incubated for 72 hrs in presence of 25 uM 6TP by alamar blue assay (Rvb = 6.4 %)2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1575616Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as combination index at 2.5 uM after 72 hrs in presence of 25 uM 6TP by alamar blue assay based Chou-Talalay method2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1575596Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by alamar blue assay2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1537670Cytotoxicity against human U937 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1575604Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as cell death at 5 uM after 72 hrs in presence of 10 uM 6TP by alamar blue assay (Rvb = 6.9%)2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1575618Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as combination index at 2.5 uM after 72 hrs in presence of 100 uM 6TP by alamar blue assay based Chou-Talalay method2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1575621Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as combination index at 5 uM after 72 hrs in presence of 50 uM 6TP by alamar blue assay based Chou-Talalay method2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1537679Cytotoxicity against human MIAPaCa2 cells assessed as cell viability at 5 uM incubated for 72 hrs in presence of 10 uM 6TP by alamar blue assay (Rvb = 6.9 %)2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1575605Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as cell death at 5 uM after 72 hrs in presence of 25 uM 6TP by alamar blue assay (Rvb = 6.4%)2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1575600Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as cell death at 2.5 uM after 72 hrs in presence of 10 uM 6TP by alamar blue assay (Rvb = 6.9%)2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1537696Cytotoxicity against human MIAPaCa2 cells assessed as combinational index at 5 uM incubated for 72 hrs in presence of 50 uM 6TP by alamar blue assay2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1575607Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as cell death at 5 uM after 72 hrs in presence of 100 uM 6TP by alamar blue assay (Rvb = 30.7%)2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1575617Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as combination index at 2.5 uM after 72 hrs in presence of 50 uM 6TP by alamar blue assay based Chou-Talalay method2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1575602Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as cell death at 2.5 uM after 72 hrs in presence of 50 uM 6TP by alamar blue assay (Rvb = 13.8%)2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1537704Cytotoxicity against human MIAPaCa2 cells assessed as cell viability at 5 uM incubated for 72 hrs by alamar blue assay (Rvb = 0 %)2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1537681Cytotoxicity against human MIAPaCa2 cells assessed as cell viability at 5 uM incubated for 72 hrs in presence of 50 uM 6TP by alamar blue assay (Rvb = 13.8 %)2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1537678Cytotoxicity against human MIAPaCa2 cells assessed as cell viability at 2.5 uM incubated for 72 hrs in presence of 100 uM 6TP by alamar blue assay (Rvb = 30.7 %)2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1537672Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1575603Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as cell death at 2.5 uM after 72 hrs in presence of 100 uM 6TP by alamar blue assay (Rvb = 30.7%)2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1575634Synergistic antiproliferative activity against human HeLa cells at 2.5 to 5 uM after 72 hrs in presence of 6TP by alamar blue assay2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1575597Antiproliferative activity against human MIAPaCa2 cells assessed as reduction in cell viability after 72 hrs by alamar blue assay2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1537675Cytotoxicity against human MIAPaCa2 cells assessed as cell viability at 2.5 uM incubated for 72 hrs in presence of 10 uM 6TP by alamar blue assay (Rvb = 6.9 %)2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1537669Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1537673Cytotoxicity against human REH cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1537703Cytotoxicity against human MIAPaCa2 cells assessed as cell viability at 2.5 uM incubated for 72 hrs by alamar blue assay (Rvb = 0 %)2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1575619Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as combination index at 2.5 uM after 72 hrs in presence of 200 uM 6TP by alamar blue assay based Chou-Talalay method2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1537692Cytotoxicity against human MIAPaCa2 cells assessed as combinational index at 2.5 uM incubated for 72 hrs in presence of 50 uM 6TP by alamar blue assay2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1537695Cytotoxicity against human MIAPaCa2 cells assessed as combinational index at 5 uM incubated for 72 hrs in presence of 25 uM 6TP by alamar blue assay2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1575635Synergistic antiproliferative activity against human A549 cells at 2.5 to 5 uM after 72 hrs in presence of 6TP by alamar blue assay2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1537671Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1575623Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as combination index at 5 uM after 72 hrs in presence of 200 uM 6TP by alamar blue assay based Chou-Talalay method2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1537674Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1575601Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as cell death at 2.5 uM after 72 hrs in presence of 25 uM 6TP by alamar blue assay (Rvb = 6.4%)2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1537697Cytotoxicity against human MIAPaCa2 cells assessed as combinational index at 5 uM incubated for 72 hrs in presence of 100 uM 6TP by alamar blue assay2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1537698Cytotoxicity against human MIAPaCa2 cells assessed as combinational index at 5 uM incubated for 72 hrs in presence of 200 uM 6TP by alamar blue assay2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1575620Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as combination index at 5 uM after 72 hrs in presence of 25 uM 6TP by alamar blue assay based Chou-Talalay method2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1575632Synergistic antiproliferative activity against human U937 cells at 2.5 to 5 uM after 72 hrs in presence of 6TP by alamar blue assay based Chou-Talalay method2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1575622Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as combination index at 5 uM after 72 hrs in presence of 100 uM 6TP by alamar blue assay based Chou-Talalay method2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1575636Synergistic antiproliferative activity against human REH cells at 2.5 to 5 uM uM after 72 hrs in presence 6TP by alamar blue assay based alamar blue assay2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
AID1537676Cytotoxicity against human MIAPaCa2 cells assessed as cell viability at 2.5 uM incubated for 72 hrs in presence of 25 uM 6TP by alamar blue assay (Rvb = 6.4 %)2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1537682Cytotoxicity against human MIAPaCa2 cells assessed as cell viability at 5 uM incubated for 72 hrs in presence of 100 uM 6TP by alamar blue assay (Rvb = 30.7 %)2019MedChemComm, Aug-01, Volume: 10, Issue:8
The winding road of the uvaretin class of natural products: from total synthesis to bioactive agent discovery.
AID1575606Synergistic antiproliferative activity against human MIAPaCa2 cells assessed as cell death at 5 uM after 72 hrs in presence of 50 uM 6TP by alamar blue assay (Rvb = 13.8%)2019MedChemComm, May-01, Volume: 10, Issue:5
New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's6 (60.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.23

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.23 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.63 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.23)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
1-anilino-8-naphthalenesulfonate
1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd. 8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.		2.0610aminonaphthalene;
naphthalenesulfonic acid		fluorescent probe
pd 98059
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source. 2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.		2.0310aromatic amine;
monomethoxyflavone		EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector
carbon tetrachloride
Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed). tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.		2.0610chlorocarbon;
chloromethanes		hepatotoxic agent;
refrigerant
chlorin
chlorin: RN given refers to parent cpd; structure. chlorin : A tetrapyrrole fundamental parent that is obtained by formal hydrogenation across the 2,3-double bond of porphyrin.		2.110
xanthoxyline
xanthoxyline: isolated from Sebastiania schottiana (Euphorbiaceae); structure given in first source; also present in Xanthoxylum, Rutaceae, Artemisia and other plants		2.2110carboxylic ester
2,4,6-trihydroxyacetophenone
monoacetylphloroglucinol: structure in first source. 2',4',6'-trihydroxyacetophenone : A benzenetriol that is acetophenone in which the hydrogens at positions 2, 4, and 6 on the phenyl group are replaced by hydroxy groups. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of acidic glycans and glycopeptides.		2.2110aromatic ketone;
benzenetriol;
methyl ketone		MALDI matrix material;
plant metabolite
uvaretin
uvaretin: chloroform extract of Uvaria acuminata Oliv.; structure. uvaretin : A member of the class of dihydrochalcones that is 1,3-diphenylpropan-1-one in which the phenyl group that is bonded to the carbonyl group is substituted by hydroxy groups at positions 2 and 4, an o-hydroxybenzyl group at position 3, and a methoxy group at position 6. A cytotoxic natural product found particularly in Uvaria acuminata and Uvaria chamae.		2.2110aromatic ether;
dihydrochalcones;
polyketide;
resorcinol		antineoplastic agent;
plant metabolite
2,4,6-trimethoxyacetophenone
2,4,6-trimethoxyacetophenone: structure in first source		2.2110
sb 203580
[no description available]		2.0310imidazoles;
monofluorobenzenes;
pyridines;
sulfoxide		EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector;
Hsp90 inhibitor;
neuroprotective agent
mercaptopurine
Mercaptopurine: An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.. purine-6-thiol : A thiol that is the tautomer of mercaptopurine.. mercaptopurine : A member of the class of purines that is 6,7-dihydro-1H-purine carrying a thione group at position 6. An adenine analogue, it is used in the treatment of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis.		2.2110aryl thiol;
purines;
thiocarbonyl compound		anticoronaviral agent;
antimetabolite;
antineoplastic agent
6-thiouric acid
6-thiouric acid: structure		2.2110oxopurine
flavokawain b
flavokawain B: from Piper methysticum Forst (Kava Kava) roots; structure in first source. flavokawain B : A member of the class of chalcones that consists of trans-chalcone substituted by hydroxy group at positions 2' and methoxy groups at positions 4' and 6'. Isolated from Piper methysticum and Piper rusbyi, it exhibits antileishmanial, anti-inflammatory and antineoplastic activities.		2.2110chalcones;
dimethoxybenzene;
phenols		anti-inflammatory agent;
antileishmanial agent;
antineoplastic agent;
apoptosis inducer;
metabolite
mocetinostat
mocetinostat: undergoing phase II clinical trials for treatment of cancer. mocetinostat : A benzamide obtained by formal condensation of the carboxy group of 4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an orally active and isotype-selective HDAC inhibitor which exhibits antitumour activity (IC50 = 0.15, 0.29, 1.66 and 0.59 muM for HDAC1, HDAC2, HDAC3 and HDAC11).		2.0610aminopyrimidine;
benzamides;
pyridines;
secondary amino compound;
secondary carboxamide;
substituted aniline		antineoplastic agent;
apoptosis inducer;
autophagy inducer;
cardioprotective agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
hepatotoxic agent
regorafenib
[no description available]		2.2110(trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
phenylureas;
pyridinecarboxamide		antineoplastic agent;
hepatotoxic agent;
tyrosine kinase inhibitor
ceruletide
Ceruletide: A specific decapeptide obtained from the skin of Hila caerulea, an Australian amphibian. Caerulein is similar in action and composition to CHOLECYSTOKININ. It stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle. It is used in paralytic ileus and as diagnostic aid in pancreatic malfunction.. ceruletide : A decapeptide comprising 5-oxoprolyl, glutamyl, aspartyl, O-sulfotyrosyl, threonyl, glycyl, tryptopyl, methionyl, aspartyl and phenylalaninamide residues in sequence. Found in the skins of certain Australian amphibians, it is an analogue of the gastrointestinal peptide hormone cholecystokinin and stimulates gastric, biliary, and pancreatic secretion. It is used in cases of paralysis of the intestine (paralytic ileus) and as a diagnostic aid in pancreatic malfunction.		2.0610oligopeptidediagnostic agent;
gastrointestinal drug
ConditionIndicatedRelationship StrengthStudiesTrials
Chronic Lung Injury
[description not available]		02.0610
Acute Edematous Pancreatitis
[description not available]		02.0610
Pancreatitis
INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.		07.0610
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