| Assay ID | Title | Year | Journal | Article |
|---|
| AID1485948 | Inhibition of human amyloid beta (1 to 42) aggregation at 100 uM after 48 hrs by transmission electron microscopic analysis | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Structure-activity relationships for flavone interactions with amyloid β reveal a novel anti-aggregatory and neuroprotective effect of 2',3',4'-trihydroxyflavone (2-D08). |
| AID1485959 | Inhibition of human amyloid beta (1 to 42) assessed as neuroprotective activity at 2 uM of amyloid beta (1 to 42)-induced toxicity in rat PC12 cells by measuring reduction in cell viability incubated 15 mins prior to amyloid beta (1 to 42) addition measur | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Structure-activity relationships for flavone interactions with amyloid β reveal a novel anti-aggregatory and neuroprotective effect of 2',3',4'-trihydroxyflavone (2-D08). |
| AID1485945 | Inhibition of human amyloid beta (1 to 42) assessed as reduction in fibrillisation AUC in cell-free solution at 100 uM measured every 10 mins for 48 hrs by Thioflavin T based fluorescence assay | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Structure-activity relationships for flavone interactions with amyloid β reveal a novel anti-aggregatory and neuroprotective effect of 2',3',4'-trihydroxyflavone (2-D08). |
| AID1485951 | Inhibition of human amyloid beta (1 to 42) assessed as neuroprotective activity up to 2 uM of amyloid beta (1 to 42)-induced toxicity in rat PC12 cells by measuring reduction in cell viability at 100 uM incubated 15 mins prior to amyloid beta (1 to 42) ad | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Structure-activity relationships for flavone interactions with amyloid β reveal a novel anti-aggregatory and neuroprotective effect of 2',3',4'-trihydroxyflavone (2-D08). |
| AID1485949 | Inhibition of human amyloid beta (1 to 42) aggregation assessed as reduction in fibril formation at 100 uM after 48 hrs by transmission electron microscopic analysis | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Structure-activity relationships for flavone interactions with amyloid β reveal a novel anti-aggregatory and neuroprotective effect of 2',3',4'-trihydroxyflavone (2-D08). |
| AID1485944 | Inhibition of human amyloid beta (1 to 42) fibrillisation in cell-free solution at 100 uM measured every 10 mins up to 48 hrs by Thioflavin T based fluorescence assay | 2017 | Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14
| Structure-activity relationships for flavone interactions with amyloid β reveal a novel anti-aggregatory and neuroprotective effect of 2',3',4'-trihydroxyflavone (2-D08). |
| AID1070224 | Inhibition of purified SUMO E1/E2 (unknown origin)-mediated conjugation of His6-SUMO-1 to fluorescent peptide FL-AR at 30 uM after 90 mins by microfluidic electrophoretic mobility shift assay | 2014 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 24, Issue:4
| Synthesis of 2',3',4'-trihydroxyflavone (2-D08), an inhibitor of protein sumoylation. |
| AID1859358 | Inhibition of His-tagged SUMO1/SUMO E1 /His-tagged Ubc9 (unknown origin)-mediated SUMOylation using FL-AR as substrate incubated for 90 mins in presence of ATP by Western blot analysis | 2022 | European journal of medicinal chemistry, Apr-05, Volume: 233 | Small-molecule inhibitors targeting small ubiquitin-like modifier pathway for the treatment of cancers and other diseases. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |