Compounds > 2'-(5''-phosphoribosyl)-5'-adenosine monophosphate
Page last updated: 2024-12-10

2'-(5''-phosphoribosyl)-5'-adenosine monophosphate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2'-(5''-phosphoribosyl)-5'-adenosine monophosphate: monomer of polyADP ribose [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

2'-(5-phosphoribosyl)-5'-AMP : An AMP-sugar in which the 2'-hydroxy group of AMP carries a 5-phospho-beta-D-ribosyl substituent. Monomer unit of poly(ADP-Rib) [poly(adenosine diphosphate ribose)]. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID3080702
CHEBI ID76110
MeSH IDM0066822

Synonyms (22)

Synonym
2'-(5''-phosphoribosyl)-5'-adenosine monophosphate
ribosyladenosine 5',5''-bis(phosphate)
5'-adenylic acid, 2'-o-(5-o-phosphono-beta-d-ribofuranosyl)-
15720-01-1
2-(5''-phosphoribosyl)-5'-amp
[(2r,3r,4r,5r)-5-(6-aminopurin-9-yl)-4-[(2s,3r,4s,5r)-3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]oxy-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate
2'-(5''-phosphoribosyl)adenosine 5'-monophosphate
2'-(1''-ribosyl)adenosine 5',5''-bis(phosphate)
EPITOPE ID:191108
2'-o-(5-o-phosphono-beta-d-ribofuranosyl)adenosine 5'-(dihydrogen phosphate)
ado(p)-rib-p
2'-(5-phosphoribosyl)adenosine 5'-monophosphate
o(2')-(o(5')-phosphono-beta-d-ribofuranosyl)-[5']adenylic acid
2'-(5-phosphoribosyl)-5'-amp
2'-o-(5-o-phosphono-beta-d-ribofuranosyl)-5'-adenylic acid
2'-(1-ribosyl)adenosine 5',5-bis(phosphate)
CHEBI:76110 ,
DTXSID50166226
2/'-(5/'/'-phosphoribosyl)-5/'-adenosine monophosphate
2'-o-[(5'-phospho)ribosyl]adenosine-5'-monophosphate
Q27145757
iso-adp-ribose
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
AMP-sugar
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.60

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.60 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.39 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.60)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
lactic acid
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed). 2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.		1.97102-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
adenosine monophosphate
Adenosine Monophosphate: Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.		3.0650adenosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		adenosine A1 receptor agonist;
cofactor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.11 (fructose-bisphosphatase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
sodium hydroxide
Sodium Hydroxide: A highly caustic substance that is used to neutralize acids and make sodium salts. (From Merck Index, 11th ed)		1.9610alkali metal hydroxide
adenosine diphosphate ribose
Adenosine Diphosphate Ribose: An ester formed between the aldehydic carbon of RIBOSE and the terminal phosphate of ADENOSINE DIPHOSPHATE. It is produced by the hydrolysis of nicotinamide-adenine dinucleotide (NAD) by a variety of enzymes, some of which transfer an ADP-ribosyl group to target proteins.		2.3820ADP-sugarEscherichia coli metabolite;
mouse metabolite
adenosine
quinquefolan B: isolated from roots of Panax quinquefolium L.; RN not in Chemline 10/87; RN from Toxlit		1.9710adenosines;
purines D-ribonucleoside		analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent
metaperiodate
Periodic Acid: A strong oxidizing agent.		1.9610iodine oxoacid
benzeneboronic acid
[no description available]		1.9610boronic acids
3-acetamidobenzamide
3-acetamidobenzamide: inhibitor of ADP-ribosyltransferase		1.9710
nad
NAD(1-) : An anionic form of nicotinamide adenine dinucleotide arising from deprotonation of the two OH groups of the diphosphate moiety.		2.3820organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Carcinoma, Ehrlich Tumor
A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.		01.9610