Compounds > 2-(acetoxyamino)-1-methyl-6-phenylimidazo(4,5-b)pyridine
Page last updated: 2024-11-13

2-(acetoxyamino)-1-methyl-6-phenylimidazo(4,5-b)pyridine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID25092289
CHEBI ID138825
SCHEMBL ID7998712
MeSH IDM0252902

Synonyms (16)

Synonym
2-(acetoxyamino)-1-methyl-6-phenylimidazo(4,5-b)pyridine
n-acetoxy-phip
2-acetoxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine
CHEBI:138825
C20287
2-acetoxyamino-phip
142784-27-8
SCHEMBL7998712
acetic acid, (1-methyl-6-phenyl-1h-imidazo[4,5-b]pyridin-2-yl)azanyl ester
n-hydroxy-phip acetyl ester
2h-imidazo[4,5-b]pyridin-2-one, 1,3-dihydro-1-methyl-6-phenyl-, o-acetyloxime
(1-methyl-6-phenyl-1h-imidazo[4,5-b]pyridin-2-yl)azanyl acetate
B7449XS5RK
1-{[(1-methyl-6-phenyl-1h-imidazo[4,5-b]pyridin-2-yl)amino]oxy}ethan-1-one
DTXSID40931642
[(1-methyl-6-phenylimidazo[4,5-b]pyridin-2-yl)amino] acetate
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
phenylpyridine
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (3)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.58

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.58 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.37 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.58)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (20.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source. PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.		2.0710imidazopyridine;
primary amino compound		carcinogenic agent;
mutagen
azomycin
azomycin: RN given refers to parent cpd with specified locant; structure		2.0710C-nitro compound;
imidazoles		antitubercular agent
2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine: directly acting genotoxic metabolite of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine. N-hydroxy-PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, hydoxyamino, and phenyl groups, respectively. The active metabolite of the dietary carcinogen PhIP.		2.0710hydroxylamine;
imidazopyridine		carcinogenic agent;
genotoxin;
human xenobiotic metabolite;
mouse metabolite;
mutagen;
neurotoxin;
rat metabolite
deoxyguanosine
[no description available]		210purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
n-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: structure given in first source; major adduct formed by the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine with DNA		210
ConditionIndicatedRelationship StrengthStudiesTrials
Genetic Predisposition
[description not available]		0210
Colorectal Cancer
[description not available]		0210
Colorectal Neoplasms
Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.		0210