2-(4-chlorophenylthio)triethylamine profile

2-(4-chlorophenylthio)triethylamine is a chemical compound with the molecular formula C13H18ClNS. It is a tertiary amine with a 4-chlorophenylthio substituent at the 2-position.

**Structure and Properties:**

* **Molecular weight:** 257.8 g/mol
* **Appearance:** Colorless to light yellow liquid
* **Solubility:** Soluble in organic solvents such as ethanol and chloroform

**Importance in Research:**

While there is limited information specifically on the research applications of 2-(4-chlorophenylthio)triethylamine, its structure and properties suggest potential uses in the following areas:

* **Organic synthesis:** The compound's reactive amine group and the 4-chlorophenylthio substituent make it a potential building block for synthesizing various organic molecules.
* **Pharmacology and medicinal chemistry:** The amine group and the aromatic substituent provide a framework for designing compounds with potential pharmacological activity.
* **Materials science:** The presence of both aliphatic and aromatic components could allow for the development of materials with unique properties, such as conductivity or surface modification.

**Potential Applications:**

* **Synthesis of novel pharmaceuticals:** The compound could be used as a starting material or intermediate in the synthesis of drugs targeting various therapeutic areas.
* **Development of new catalysts:** The amine group could be used to anchor metal ions or other catalytic functionalities.
* **Synthesis of polymers and other materials:** The presence of the 4-chlorophenylthio group could provide functionality for polymerization or surface modification.

**It's important to note that:**

* Specific research applications of 2-(4-chlorophenylthio)triethylamine may not be widely known or documented.
* Further research is needed to explore the potential of this compound in various fields.

**Safety Considerations:**

* This compound is a chemical reagent and should be handled with appropriate safety precautions.
* Avoid contact with skin, eyes, and inhalation.
* Wear protective gear, such as gloves, goggles, and a respirator, when handling.
* Consult the Material Safety Data Sheet (MSDS) for detailed safety information.

2-(4-chlorophenylthio)triethylamine: causes accumulation of lycopene at expense of other carotenoids in carotenogenic tissues; RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	26171
SCHEMBL ID	3422695
MeSH ID	M0050149

Synonym
amchem 72-a42
2-(4-chlorophenyl)sulfanyl-n,n-diethylethanamine
ethanamine, 2-((4-chlorophenyl)thio)-n,n-diethyl-
triethylamine, 2-((p-chlorophenyl)thio)-
2-(4-chlorophenylthio)triethylamine
14214-33-6
SCHEMBL3422695
DTXSID90161952
n-{2-[(4-chlorophenyl)sulfanyl]ethyl}-n,n-diethylamine
2-(4-chlorophenylthio)-triethylamine
ethanamine,2-((4-chlorophenyl)thio)-n,n-diethyl-
Z103718958

Excerpt	Reference	Relevance
"Aquatic and terrestrial fulvic acids are environmentally important because they affect the bioavailability and transport of metal ions."	( Examination of cadmium(II) complexation by the Suwannee River fulvic acid using 113Cd NMR relaxation measurements. Burton, SD; Carper, WR; Larive, CK; Otto, WH, 2001)	0.31

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	3 (16.67)	18.7374
1990's	4 (22.22)	18.2507
2000's	5 (27.78)	29.6817
2010's	1 (5.56)	24.3611
2020's	5 (27.78)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	18 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
imidazole imidazole: RN given refers to parent cpd. 1H-imidazole : An imidazole tautomer which has the migrating hydrogen at position 1.	1.97	1	imidazole
diuron Diuron: A pre-emergent herbicide.. diuron : A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which both of the hydrogens attached to one nitrogen are substituted by methyl groups, and one of the hydrogens attached to the other nitrogen is substituted by a 3,4-dichlorophenyl group.	1.99	1	3-(3,4-substituted-phenyl)-1,1-dimethylurea; dichlorobenzene	environmental contaminant; mitochondrial respiratory-chain inhibitor; photosystem-II inhibitor; urea herbicide; xenobiotic
piperonyl butoxide [no description available]	1.96	1	benzodioxoles	pesticide synergist
chloramphenicol Amphenicol: Chloramphenicol and its derivatives.	1.99	1	C-nitro compound; carboxamide; diol; organochlorine compound	antibacterial drug; antimicrobial agent; Escherichia coli metabolite; geroprotector; Mycoplasma genitalium metabolite; protein synthesis inhibitor
nitrilotriacetic acid Nitrilotriacetic Acid: A derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.)	2	1	NTA; tricarboxylic acid	carcinogenic agent; nephrotoxic agent
diphenylamine Diphenylamine: In humans it may be irritating to mucous membranes. Methemoglobinemia has been produced experimentally. In veterinary use, it is one of active ingredients in topical agents for prevention and treatment of screwworm infestation. An indicator in tests for nitrate poisoning.. diphenylamine : An aromatic amine containing two phenyl substituents. It has been used as a fungicide for the treatment of superficial scald in apples and pears, but is no longer approved for this purpose within the European Union.	2.36	2	aromatic amine; bridged diphenyl fungicide; secondary amino compound	antifungal agrochemical; antioxidant; carotogenesis inhibitor; EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor; ferroptosis inhibitor; radical scavenger
cadmium Cadmium: An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.. elemental cadmium : An element in the zinc group of the periodic table with atomic number 48, atomic mass 112, M.P. 321degreeC, and B.P. 765degreeC). An odourless, tasteless, and highly poisonous soft, ductile, lustrous metal with electropositive properties. It has eight stable isotopes: (106)Cd, (108)Cd,(110)Cd, (111)Cd, (112)Cd, (113)Cd, (114)Cd and (116)Cd, with (112)Cd and (114)Cd being the most common.	2	1	cadmium molecular entity; zinc group element atom
iodine [no description available]	2.6	1	halide anion; monoatomic iodine	human metabolite
nicotine (S)-nicotine : A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum.	2.87	4	3-(1-methylpyrrolidin-2-yl)pyridine	anxiolytic drug; biomarker; immunomodulator; mitogen; neurotoxin; nicotinic acetylcholine receptor agonist; peripheral nervous system drug; phytogenic insecticide; plant metabolite; psychotropic drug; teratogenic agent; xenobiotic
bradykinin [no description available]	1.98	1	oligopeptide	human blood serum metabolite; vasodilator agent
lycopene [no description available]	2.91	4	acyclic carotene	antioxidant; plant metabolite
violaxanthin violaxanthin: a carotene epoxide that is precursor to capsanthin; one of 3 xanthophylls involved in evolution of plastids of green plants (oxygen evolution); 3 (violaxanthin, zeaxanthin & antheraxanthin) participate in series of photo-induced interconversions known as ''violaxanthin cycle''; structure; cleavage of 9-cis-epoxycarotenoids (violaxanthin) to xanthoxin, catalyzed by 9-cis-epoxycarotenoid dioxygenase, is the key regulatory step of ABSCISIC ACID biosynthesis. violaxanthin : An epoxycarotenol that is 5,5',6,6'-tetrahydro-5,6:5',6'-diepoxy-beta,beta-carotene substituted by hydroxy groups at positions 3 and 3'. It is the naturally occurring xanthophyll pigment found in a variety of plants.. all-trans-violaxanthin : The all-trans-stereoisomer of violaxanthin.	1.99	1	violaxanthin	food colouring
nadp [no description available]	1.97	1
nitenpyram nitenpyram: a nitromethylene neonicotinoid insecticide; structure in first source. (E)-nitenpyram : A nitenpyram in which the double bond has E configuration.. nitenpyram : A C-nitro compound consisting of 2-nitroethene-1,1-diamine where one of the nitrogens bears ethyl and (6-chloro-3-pyridinyl)methyl while the other nitrogen carries a methyl group.	2.41	1	chloropyridyl insecticide; nitenpyram
beta carotene beta Carotene: A carotenoid that is a precursor of VITAMIN A. Beta carotene is administered to reduce the severity of photosensitivity reactions in patients with erythropoietic protoporphyria (PORPHYRIA, ERYTHROPOIETIC).. provitamin A : A provitamin that can be converted into vitamin A by enzymes from animal tissues.	2.92	4	carotenoid beta-end derivative; cyclic carotene	antioxidant; biological pigment; cofactor; ferroptosis inhibitor; human metabolite; mouse metabolite; plant metabolite; provitamin A
neurosporene [no description available]	1.96	1	acyclic carotene
zeaxanthin Zeaxanthins: Carotenoids found in fruits and vegetables. Zeaxanthin accumulates in the MACULA LUTEA.	1.99	1	carotenol	antioxidant; bacterial metabolite; cofactor
nitrofurazone Nitrofurazone: A topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial WOUNDS AND INJURIES and skin infections. Nitrofurazone has also been administered orally in the treatment of TRYPANOSOMIASIS.. nitrofurazone : A semicarbazone resulting from the formal condensation of semicarbazide with 5-nitrofuraldehyde. A broad spectrum antibacterial drug, although with little activity against Pseudomonas species, it is used as a local application for burns, ulcers, wounds and skin infections.	2.41	1
abscisic acid Abscisic Acid: Abscission-accelerating plant growth substance isolated from young cotton fruit, leaves of sycamore, birch, and other plants, and from potatoes, lemons, avocados, and other fruits.. (S)-2-trans-abscisic acid : A 2-trans-abscisic acid with (S)-configuration at the chiral centre.. (+)-abscisic acid : The naturally occurring (1'S)-(+) enantiomer of abscisic acid. It is an important sesquiterpenoid plant hormone which acts as a regulator of plant responses to environmental stresses such as drought and cold.	2.03	1	2-trans-abscisic acid
zeacarotene zeacarotene: RN given refers to cpd without isomeric designation	1.96	1
icatibant icatibant: a potent bradykinin (B2) receptor antagonist; WIN 65365 is an L-Tic(7) stereoisomer. icatibant : A ten-membered synthetic oligopeptide consisting of D-Arg, Arg, Pro, Hyp, Gly, Thi, Ser, D-Tic, Oic, and Arg residues joined in sequrence. A bradykinin receptor antagonist used as its acetate salt for the treatment of acute attacks of hereditary angioedema in adult patients.	1.98	1
chlorophyll a Chlorophyll: Porphyrin derivatives containing magnesium that act to convert light energy in photosynthetic organisms.. chlorophyll : A family of magnesium porphyrins, defined by the presence of a fifth ring beyond the four pyrrole-like rings. The rings can have various side chains which usually include a long phytol chain.	2.03	1	chlorophyll; methyl ester	cofactor

Condition	Indicated	Relationship Strength	Studies	Trials
Preterm Birth [description not available]	0	2.6	1	0
Premature Birth CHILDBIRTH before 37 weeks of PREGNANCY (259 days from the first day of the mother's last menstrual period, or 245 days after FERTILIZATION).	0	2.6	1	0

2-(4-chlorophenylthio)triethylamine

Description

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Synonyms (12)

Research Excerpts

Bioavailability

Research

Studies (18)

Market Indicators

Research Demand Index: 12.52

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