| Substance | Description | Relationhip Strength | Studies | Trials | Classes | Roles |
|---|
| quinacrine | [no description available] | low | 0 | 0 | acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound | antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor |
| vanilmandelic acid | [no description available] | low | 0 | 0 | 2-hydroxy monocarboxylic acid;
aromatic ether;
phenols | human metabolite |
| 4-(2,4-dichlorophenoxy)butyric acid | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
organochlorine compound | agrochemical;
phenoxy herbicide;
synthetic auxin |
| win 52035 | [no description available] | low | 0 | 0 | aromatic ether | |
| win 52084 | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(nonyloxy)tryptamine | [no description available] | low | 0 | 0 | aromatic ether;
primary amino compound;
tryptamines | serotonergic agonist |
| methylbufotenin | [no description available] | low | 0 | 0 | aromatic ether;
tertiary amino compound;
tryptamine alkaloid | hallucinogen;
plant metabolite |
| 5-methoxytryptamine | [no description available] | low | 0 | 0 | aromatic ether;
primary amino compound;
tryptamines | 5-hydroxytryptamine 2A receptor agonist;
5-hydroxytryptamine 2B receptor agonist;
5-hydroxytryptamine 2C receptor agonist;
antioxidant;
cardioprotective agent;
human metabolite;
mouse metabolite;
neuroprotective agent;
radiation protective agent;
serotonergic agonist |
| ro 48-8071 | [no description available] | low | 0 | 0 | aromatic ether;
aromatic ketone;
bromobenzenes;
monofluorobenzenes;
olefinic compound;
tertiary amino compound | antineoplastic agent;
EC 5.4.99.7 (lanosterol synthase) inhibitor |
| rtki cpd | [no description available] | low | 0 | 0 | aromatic ether;
monochlorobenzenes;
quinazolines | antineoplastic agent;
antiviral agent;
epidermal growth factor receptor antagonist;
geroprotector |
| amsacrine | [no description available] | low | 0 | 0 | acridines;
aromatic ether;
sulfonamide | antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor |
| aristolochic acid i | [no description available] | low | 0 | 0 | aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound | carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin |
| 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one | [no description available] | low | 0 | 0 | aromatic ether;
benzoxazine;
cyclic hydroxamic acid;
lactol | allelochemical;
plant metabolite |
| bufetolol | [no description available] | low | 0 | 0 | aromatic ether | |
| bufexamac | [no description available] | low | 0 | 0 | aromatic ether;
hydroxamic acid | antipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| bunitrolol | [no description available] | low | 0 | 0 | aromatic ether | |
| bupranolol | [no description available] | low | 0 | 0 | aromatic ether | |
| verapamil | [no description available] | low | 0 | 0 | aromatic ether;
nitrile;
polyether;
tertiary amino compound | |
| cgp 12177 | [no description available] | low | 0 | 0 | aromatic ether;
benzimidazoles;
secondary alcohol;
secondary amino compound | beta-adrenergic antagonist |
| ciglitazone | [no description available] | low | 0 | 0 | aromatic ether;
thiazolidinone | antineoplastic agent;
insulin-sensitizing drug |
| cirazoline | [no description available] | low | 0 | 0 | aromatic ether | |
| clofibrate | [no description available] | low | 0 | 0 | aromatic ether;
ethyl ester;
monochlorobenzenes | anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist |
| clofibric acid | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
monochlorobenzenes | anticholesteremic drug;
antilipemic drug;
antineoplastic agent;
herbicide;
marine xenobiotic metabolite;
PPARalpha agonist |
| colchicine, (+-)-isomer | [no description available] | low | 0 | 0 | acetamides;
alkaloid;
aromatic ether;
carbotricyclic compound | microtubule-destabilising agent;
plant metabolite |
| croconazole | [no description available] | low | 0 | 0 | aromatic ether;
conazole antifungal drug;
imidazole antifungal drug;
monochlorobenzenes | |
| cypermethrin | [no description available] | low | 0 | 0 | aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound | agrochemical;
molluscicide;
pyrethroid ester acaricide;
pyrethroid ester insecticide |
| racemethorphan | [no description available] | low | 0 | 0 | aromatic ether;
morphinane alkaloid;
morphinane-like compound;
organic heterotetracyclic compound | |
| dibucaine | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid amide;
tertiary amino compound | topical anaesthetic |
| dilacor xr | [no description available] | low | 0 | 0 | acetate ester;
aromatic ether;
benzothiazepine;
lactam;
tertiary amino compound | |
| domiphen | [no description available] | low | 0 | 0 | aromatic ether | |
| donepezil | [no description available] | low | 0 | 0 | aromatic ether;
indanones;
piperidines;
racemate | EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
nootropic agent |
| epirizole | [no description available] | low | 0 | 0 | aromatic ether | |
| ethacrynic acid | [no description available] | low | 0 | 0 | aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid | EC 2.5.1.18 (glutathione transferase) inhibitor;
ion transport inhibitor;
loop diuretic |
| ethoxyquin | [no description available] | low | 0 | 0 | aromatic ether;
quinolines | antifungal agrochemical;
food antioxidant;
genotoxin;
geroprotector;
herbicide;
Hsp90 inhibitor;
neuroprotective agent;
UDP-glucuronosyltransferase activator |
| ethoxzolamide | [no description available] | low | 0 | 0 | aromatic ether;
benzothiazoles;
sulfonamide | antiglaucoma drug;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor |
| 2-hexyloxybenzamide | [no description available] | low | 0 | 0 | aromatic ether;
benzamides | antifungal agent |
| carbonyl cyanide p-trifluoromethoxyphenylhydrazone | [no description available] | low | 0 | 0 | aromatic ether;
hydrazone;
nitrile;
organofluorine compound | ATP synthase inhibitor;
geroprotector;
ionophore |
| fenofibrate | [no description available] | low | 0 | 0 | aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes | antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic |
| fenvalerate | [no description available] | low | 0 | 0 | aromatic ether;
carboxylic ester;
monochlorobenzenes | pyrethroid ester acaricide;
pyrethroid ester insecticide |
| flecainide | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid amide;
organofluorine compound;
piperidines | anti-arrhythmia drug |
| fluoxetine | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
secondary amino compound | |
| gallamine triethiodide | [no description available] | low | 0 | 0 | aromatic ether | |
| gemfibrozil | [no description available] | low | 0 | 0 | aromatic ether | antilipemic drug |
| haloprogin | [no description available] | low | 0 | 0 | aromatic ether | |
| indomethacin | [no description available] | low | 0 | 0 | aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole | analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic |
| ipriflavone | [no description available] | low | 0 | 0 | aromatic ether;
isoflavones | bone density conservation agent |
| ly 171883 | [no description available] | low | 0 | 0 | acetophenones;
aromatic ether;
phenols;
tetrazoles | anti-asthmatic drug;
leukotriene antagonist |
| mephenesin | [no description available] | low | 0 | 0 | aromatic ether;
glycerol ether | |
| methocarbamol | [no description available] | low | 0 | 0 | aromatic ether;
carbamate ester;
secondary alcohol | |
| methoctramine | [no description available] | low | 0 | 0 | aromatic ether;
tetramine | muscarinic antagonist |
| methoxsalen | [no description available] | low | 0 | 0 | aromatic ether;
psoralens | antineoplastic agent;
cross-linking reagent;
dermatologic drug;
photosensitizing agent;
plant metabolite |
| metoprolol | [no description available] | low | 0 | 0 | aromatic ether;
propanolamine;
secondary alcohol;
secondary amino compound | antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
geroprotector;
xenobiotic |
| mexiletine | [no description available] | low | 0 | 0 | aromatic ether;
primary amino compound | anti-arrhythmia drug |
| midodrine | [no description available] | low | 0 | 0 | amino acid amide;
aromatic ether;
secondary alcohol | alpha-adrenergic agonist;
prodrug;
sympathomimetic agent;
vasoconstrictor agent |
| clorgyline | [no description available] | low | 0 | 0 | aromatic ether;
dichlorobenzene;
terminal acetylenic compound;
tertiary amino compound | antidepressant;
EC 1.4.3.4 (monoamine oxidase) inhibitor |
| nefazodone | [no description available] | low | 0 | 0 | aromatic ether;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
triazoles | alpha-adrenergic antagonist;
analgesic;
antidepressant;
serotonergic antagonist;
serotonin uptake inhibitor |
| nimesulide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound;
sulfonamide | cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug |
| nisoxetine | [no description available] | low | 0 | 0 | aromatic ether;
secondary amino compound | adrenergic uptake inhibitor;
antidepressant |
| n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound;
sulfonamide | antineoplastic agent;
cyclooxygenase 2 inhibitor |
| omeprazole | [no description available] | low | 0 | 0 | aromatic ether;
benzimidazoles;
pyridines;
sulfoxide | |
| oxprenolol | [no description available] | low | 0 | 0 | aromatic ether | |
| pantoprazole | [no description available] | low | 0 | 0 | aromatic ether;
benzimidazoles;
organofluorine compound;
pyridines;
sulfoxide | anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
environmental contaminant;
xenobiotic |
| pd 153035 | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
bromobenzenes;
quinazolines;
secondary amino compound | EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
epidermal growth factor receptor antagonist |
| pentamidine | [no description available] | low | 0 | 0 | aromatic ether;
carboxamidine;
diether | anti-inflammatory agent;
antifungal agent;
calmodulin antagonist;
chemokine receptor 5 antagonist;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
NMDA receptor antagonist;
S100 calcium-binding protein B inhibitor;
trypanocidal drug;
xenobiotic |
| phenacetin | [no description available] | low | 0 | 0 | acetamides;
aromatic ether | cyclooxygenase 3 inhibitor;
non-narcotic analgesic;
peripheral nervous system drug |
| pioglitazone | [no description available] | low | 0 | 0 | aromatic ether;
pyridines;
thiazolidinediones | antidepressant;
cardioprotective agent;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hypoglycemic agent;
insulin-sensitizing drug;
PPARgamma agonist;
xenobiotic |
| piretanide | [no description available] | low | 0 | 0 | aromatic ether | |
| pramoxine | [no description available] | low | 0 | 0 | aromatic ether;
morpholines | local anaesthetic |
| prazosin | [no description available] | low | 0 | 0 | aromatic ether;
furans;
monocarboxylic acid amide;
piperazines;
quinazolines | alpha-adrenergic antagonist;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor |
| primaquine | [no description available] | low | 0 | 0 | aminoquinoline;
aromatic ether;
N-substituted diamine | antimalarial |
| proglumetacin | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
carboxylic ester;
monochlorobenzenes;
N-acylindole;
N-alkylpiperazine | antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
lipoxygenase inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug |
| propoxur | [no description available] | low | 0 | 0 | aromatic ether;
carbamate ester | acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| pyrilamine | [no description available] | low | 0 | 0 | aromatic ether;
ethylenediamine derivative | H1-receptor antagonist |
| sulfadimethoxine | [no description available] | low | 0 | 0 | aromatic ether;
pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide | antiinfective agent;
antimicrobial agent;
drug allergen;
environmental contaminant;
xenobiotic |
| tetrahydropapaverine | [no description available] | low | 0 | 0 | aromatic ether;
benzylisoquinoline alkaloid;
benzyltetrahydroisoquinoline;
polyether;
secondary amino compound | |
| tilorone | [no description available] | low | 0 | 0 | aromatic ether;
diether;
fluoren-9-ones;
tertiary amino compound | anti-inflammatory agent;
antineoplastic agent;
antiviral agent;
interferon inducer;
nicotinic acetylcholine receptor agonist |
| ultram | [no description available] | low | 0 | 0 | aromatic ether;
tertiary alcohol;
tertiary amino compound | |
| triclosan | [no description available] | low | 0 | 0 | aromatic ether;
dichlorobenzene;
monochlorobenzenes;
phenols | antibacterial agent;
antimalarial;
drug allergen;
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
fungicide;
persistent organic pollutant;
xenobiotic |
| viloxazine | [no description available] | low | 0 | 0 | aromatic ether | |
| wb 4101 | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxine;
secondary amino compound | alpha-adrenergic antagonist |
| 3,3',5-triiodothyropropionic acid | [no description available] | low | 0 | 0 | aromatic ether | |
| methacetin | [no description available] | low | 0 | 0 | acetamides;
aromatic ether | |
| mestranol | [no description available] | low | 0 | 0 | 17beta-hydroxy steroid;
aromatic ether;
terminal acetylenic compound | prodrug;
xenoestrogen |
| visnagin | [no description available] | low | 0 | 0 | aromatic ether;
furanochromone;
polyketide | anti-inflammatory agent;
antihypertensive agent;
EC 1.1.1.37 (malate dehydrogenase) inhibitor;
phytotoxin;
plant metabolite;
vasodilator agent |
| 2-tert-butyl-4-hydroxyanisole | [no description available] | low | 0 | 0 | aromatic ether;
phenols | |
| mecoprop | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
monochlorobenzenes | |
| phenetidine | [no description available] | low | 0 | 0 | aromatic ether;
substituted aniline | |
| 2-methyl-4-chlorophenoxy gamma-butyric acid | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
monochlorobenzenes | environmental contaminant;
phenoxy herbicide;
xenobiotic |
| 4-bromophenyl phenyl ether | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound | |
| di-(4-aminophenyl)ether | [no description available] | low | 0 | 0 | aromatic ether | |
| phenyl ether | [no description available] | low | 0 | 0 | aromatic ether | plant metabolite |
| diglycidyl resorcinol ether | [no description available] | low | 0 | 0 | aromatic ether | |
| phenetole | [no description available] | low | 0 | 0 | aromatic ether | |
| scoparone | [no description available] | low | 0 | 0 | aromatic ether;
coumarins | anti-allergic agent;
anti-inflammatory agent;
antihypertensive agent;
antilipemic drug;
immunosuppressive agent;
plant metabolite |
| dimethoxyphenylethylamine | [no description available] | low | 0 | 0 | alkaloid;
aromatic ether;
phenylethylamine | allergen;
plant metabolite |
| dichlorprop | [no description available] | low | 0 | 0 | aromatic ether;
dichlorobenzene;
monocarboxylic acid | |
| 3-tert-butyl-4-hydroxyanisole | [no description available] | low | 0 | 0 | aromatic ether;
phenols | antioxidant;
human xenobiotic metabolite |
| ethyl vanillin | [no description available] | low | 0 | 0 | aromatic ether;
benzaldehydes;
phenols | antioxidant;
flavouring agent |
| benzethonium chloride | [no description available] | low | 0 | 0 | aromatic ether;
chloride salt;
quaternary ammonium salt | antibacterial agent;
antifungal agent;
antiseptic drug;
antiviral agent;
disinfectant |
| peucedanin | [no description available] | low | 0 | 0 | aromatic ether;
furanocoumarin;
lactone | plant metabolite |
| phenetidine | [no description available] | low | 0 | 0 | aromatic ether;
primary amino compound;
substituted aniline | drug metabolite |
| 6-methoxybenzoxazolinone | [no description available] | low | 0 | 0 | aromatic ether;
benzoxazole | antibacterial agent;
anticonvulsant;
antifungal agent;
muscle relaxant;
plant metabolite |
| 3-anisidine | [no description available] | low | 0 | 0 | aromatic ether;
substituted aniline | |
| domiphen bromide | [no description available] | low | 0 | 0 | aromatic ether | |
| dibrompropamidine | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-Ethoxyphenol | [no description available] | low | 0 | 0 | aromatic ether;
phenols | |
| bulbocapnine | [no description available] | low | 0 | 0 | aporphine alkaloid;
aromatic ether;
oxacycle;
phenols | EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor;
EC 1.4.3.22 (diamine oxidase) inhibitor;
plant metabolite |
| benzydamine | [no description available] | low | 0 | 0 | aromatic ether;
indazoles;
tertiary amino compound | analgesic;
central nervous system stimulant;
hallucinogen;
local anaesthetic;
non-steroidal anti-inflammatory drug |
| xylocholine | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-methoxycatechol | [no description available] | low | 0 | 0 | aromatic ether;
catechols | G-protein-coupled receptor agonist |
| 2-phenoxypropanoic acid | [no description available] | low | 0 | 0 | aromatic ether;
carboxylic acid | |
| 6-methoxyquinoline | [no description available] | low | 0 | 0 | aromatic ether;
quinolines | |
| metaxalone | [no description available] | low | 0 | 0 | aromatic ether | |
| heliamine | [no description available] | low | 0 | 0 | aromatic ether;
diether;
isoquinoline alkaloid;
isoquinolines | plant metabolite |
| 2,4,6-trichlorophenyl 4-nitrophenyl ether | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound;
chlorobenzenes | EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide |
| etridiazol | [no description available] | low | 0 | 0 | aromatic ether;
organochlorine compound;
thiadiazole antifungal agent;
thiadiazoles | antifungal agrochemical;
nitrification inhibitor |
| toliprolol | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-methoxyindoleacetic acid | [no description available] | low | 0 | 0 | aromatic ether;
indole-3-acetic acids | antibacterial agent;
Brassica napus metabolite;
carcinogenic agent;
human urinary metabolite;
marine xenobiotic metabolite;
rat metabolite |
| iproclozide | [no description available] | low | 0 | 0 | aromatic ether | |
| phenoxyacetic acid | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid | allergen;
Aspergillus metabolite;
human xenobiotic metabolite;
plant growth retardant |
| nafenopin | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid | |
| methyl vanillate | [no description available] | low | 0 | 0 | aromatic ether;
benzoate ester;
phenols | antioxidant;
plant metabolite |
| 5-methoxyindole-2-carboxylic acid | [no description available] | low | 0 | 0 | aromatic ether;
indolecarboxylic acid | EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitor;
hypoglycemic agent;
plant metabolite |
| 2-isopropoxyphenol | [no description available] | low | 0 | 0 | aromatic ether;
phenols | |
| dehydroemetine | [no description available] | low | 0 | 0 | aromatic ether;
isoquinolines;
pyridoisoquinoline | antileishmanial agent;
antimalarial;
antiprotozoal drug |
| 1,2-epoxy-3-(p-nitrophenoxy)propane | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound;
epoxide | |
| laurolitsine | [no description available] | low | 0 | 0 | aporphine alkaloid;
aromatic ether;
phenols | HIV-1 integrase inhibitor;
metabolite |
| metocurine iodide | [no description available] | low | 0 | 0 | aromatic ether | |
| ac 45594 | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-phenoxybenzylalcohol | [no description available] | low | 0 | 0 | aromatic ether;
benzyl alcohols | marine xenobiotic metabolite |
| devrinol | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid amide;
naphthalenes | |
| fluorodifen | [no description available] | low | 0 | 0 | aromatic ether | |
| acridine half-mustard | [no description available] | low | 0 | 0 | aminoacridines;
aromatic ether;
organochlorine compound;
secondary amino compound | mutagen |
| precocene i | [no description available] | low | 0 | 0 | aromatic ether;
chromenes | plant metabolite;
precocenes |
| oxadiazon | [no description available] | low | 0 | 0 | aromatic ether | |
| lofexidine | [no description available] | low | 0 | 0 | aromatic ether;
carboxamidine;
dichlorobenzene;
imidazoles | alpha-adrenergic agonist;
antihypertensive agent |
| alclofenac | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
monochlorobenzenes | drug allergen;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| phenylglycidyl ether | [no description available] | low | 0 | 0 | aromatic ether | |
| phenoxyethanol | [no description available] | low | 0 | 0 | aromatic ether;
glycol ether;
primary alcohol | antiinfective agent;
central nervous system depressant |
| metipranolol | [no description available] | low | 0 | 0 | acetate ester;
aromatic ether;
propanolamine;
secondary amino compound | anti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist |
| silybin | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxine;
flavonolignan;
polyphenol;
secondary alpha-hydroxy ketone | antineoplastic agent;
antioxidant;
hepatoprotective agent;
plant metabolite |
| oxamethacin | [no description available] | low | 0 | 0 | aromatic ether;
hydroxamic acid;
N-acylindole;
organochlorine compound | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| canadine | [no description available] | low | 0 | 0 | aromatic ether;
berberine alkaloid;
organic heteropentacyclic compound;
oxacycle | |
| 7-ethoxycoumarin | [no description available] | low | 0 | 0 | aromatic ether;
coumarins | |
| medifoxamine | [no description available] | low | 0 | 0 | aromatic ether | |
| chlormethoxynil | [no description available] | low | 0 | 0 | aromatic ether | |
| climbazole | [no description available] | low | 0 | 0 | aromatic ether;
hemiaminal ether;
imidazoles;
ketone;
monochlorobenzenes | |
| 4-hexyloxyaniline | [no description available] | low | 0 | 0 | aromatic ether;
substituted aniline | |
| ticrynafen | [no description available] | low | 0 | 0 | aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid;
thiophenes | antihypertensive agent;
hepatotoxic agent;
loop diuretic |
| 2-(4-(2,4-dichlorophenoxy)phenoxy)propionic acid | [no description available] | low | 0 | 0 | aromatic ether;
dichlorobenzene;
diether;
monocarboxylic acid | |
| bezafibrate | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid amide;
monocarboxylic acid;
monochlorobenzenes | antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic |
| oxyfluorofen | [no description available] | low | 0 | 0 | aromatic ether | EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide |
| triadimefon | [no description available] | low | 0 | 0 | aromatic ether;
hemiaminal ether;
ketone;
monochlorobenzenes;
triazoles | |
| levobunolol | [no description available] | low | 0 | 0 | aromatic ether;
cyclic ketone;
propanolamine | antiglaucoma drug;
beta-adrenergic antagonist |
| dichlorfop-methyl | [no description available] | low | 0 | 0 | aromatic ether;
dichlorobenzene;
diether;
methyl ester | |
| decamethrin | [no description available] | low | 0 | 0 | aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organobromine compound | agrochemical;
antifeedant;
calcium channel agonist;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
pyrethroid ester insecticide |
| triadimenol | [no description available] | low | 0 | 0 | aromatic ether;
conazole fungicide;
hemiaminal ether;
monochlorobenzenes;
secondary alcohol;
triazole fungicide | antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
xenobiotic metabolite |
| triclopyr | [no description available] | low | 0 | 0 | aromatic ether;
chloropyridine;
monocarboxylic acid | agrochemical;
environmental contaminant;
herbicide;
xenobiotic |
| prenalterol | [no description available] | low | 0 | 0 | aromatic ether | |
| st 1059 | [no description available] | low | 0 | 0 | aromatic ether;
primary amino compound;
secondary alcohol | alpha-adrenergic agonist;
sympathomimetic agent;
vasoconstrictor agent |
| paroxetine | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxoles;
organofluorine compound;
piperidines | antidepressant;
anxiolytic drug;
hepatotoxic agent;
P450 inhibitor;
serotonin uptake inhibitor |
| acifluorfen | [no description available] | low | 0 | 0 | aromatic ether;
benzoic acids;
C-nitro compound;
monocarboxylic acid;
organochlorine compound;
organofluorine compound | agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide |
| bopindolol | [no description available] | low | 0 | 0 | aromatic ether;
benzoate ester;
methylindole;
secondary amino compound | |
| fenpropathrin, (+-)-isomer | [no description available] | low | 0 | 0 | aromatic ether;
cyclopropanecarboxylate ester | agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide |
| triflumuron | [no description available] | low | 0 | 0 | aromatic ether;
benzoylurea insecticide;
monochlorobenzenes;
organofluorine compound | |
| flutolanil | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
benzamides;
benzanilide fungicide | antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor |
| fenoxaprop ethyl | [no description available] | low | 0 | 0 | aromatic ether | |
| triclabendazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 4,5-amino-3,5-dichloro-6-fluoro-2-pyridinyloxyacetic acid | [no description available] | low | 0 | 0 | aminopyridine;
aromatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound | environmental contaminant;
herbicide;
xenobiotic |
| fluvalinate | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
nitrile;
organochlorine acaricide;
organochlorine insecticide;
organofluorine acaricide;
organofluorine insecticide | agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide |
| haloxyfop | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound;
pyridines | |
| fluazifop-butyl | [no description available] | low | 0 | 0 | aromatic ether;
carboxylic ester;
organofluorine compound;
pyridines | |
| fomesafen | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-sulfonylcarboxamide;
organofluorine compound;
phenols | agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide |
| fenoxycarb | [no description available] | low | 0 | 0 | aromatic ether;
carbamate ester | environmental contaminant;
insecticide;
juvenile hormone mimic;
xenobiotic |
| quizalofop-ethyl | [no description available] | low | 0 | 0 | aromatic ether;
ethyl ester;
organochlorine compound;
quinoxaline derivative | |
| cetamolol | [no description available] | low | 0 | 0 | aromatic ether | |
| atomoxetine | [no description available] | low | 0 | 0 | aromatic ether;
secondary amino compound;
toluenes | adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
xenobiotic |
| methyl bensulfuron | [no description available] | low | 0 | 0 | aromatic ether;
methyl ester;
N-sulfonylurea;
pyrimidines | agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide |
| itraconazole | [no description available] | low | 0 | 0 | aromatic ether;
conazole antifungal drug;
cyclic ketal;
dichlorobenzene;
dioxolane;
N-arylpiperazine;
triazole antifungal drug;
triazoles | EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
Hedgehog signaling pathway inhibitor;
P450 inhibitor |
| loxtidine | [no description available] | low | 0 | 0 | aromatic ether;
piperidines;
primary alcohol;
triazoles | H2-receptor antagonist |
| disoxaril | [no description available] | low | 0 | 0 | aromatic ether | |
| chlorimuron ethyl | [no description available] | low | 0 | 0 | aromatic ether;
ethyl ester;
N-sulfonylurea;
organochlorine pesticide;
pyrimidines;
sulfamoylbenzoate | agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
proherbicide |
| tepoxalin | [no description available] | low | 0 | 0 | aromatic ether;
hydroxamic acid;
monochlorobenzenes;
pyrazoles | antipyretic;
apoptosis inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
immunomodulator;
lipoxygenase inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| esmolol | [no description available] | low | 0 | 0 | aromatic ether;
ethanolamines;
methyl ester;
secondary alcohol;
secondary amino compound | |
| pioglitazone hydrochloride | [no description available] | low | 0 | 0 | aromatic ether | |
| aripiprazole | [no description available] | low | 0 | 0 | aromatic ether;
delta-lactam;
dichlorobenzene;
N-alkylpiperazine;
N-arylpiperazine;
quinolone | drug metabolite;
H1-receptor antagonist;
second generation antipsychotic;
serotonergic agonist |
| sulfametrole | [no description available] | low | 0 | 0 | aromatic ether;
substituted aniline;
sulfonamide antibiotic;
thiadiazoles | |
| propamidine | [no description available] | low | 0 | 0 | aromatic ether;
guanidines;
polyether | antimicrobial agent;
antiseptic drug |
| hexamidine | [no description available] | low | 0 | 0 | aromatic ether;
guanidines;
polyether | antimicrobial agent;
antiseptic drug |
| o-4-methylthymine | [no description available] | low | 0 | 0 | aromatic ether;
methylthymine | human metabolite |
| fenclofenac | [no description available] | low | 0 | 0 | aromatic ether | |
| tetraiodothyroacetic acid | [no description available] | low | 0 | 0 | 2-halophenol;
aromatic ether;
iodophenol;
monocarboxylic acid | apoptosis inducer;
human metabolite;
thyroid hormone |
| fluazuron | [no description available] | low | 0 | 0 | aromatic ether;
chloropyridine;
monochlorobenzenes;
N-acylurea;
organochlorine acaricide;
organofluorine acaricide;
phenylureas | acaricide;
mite growth regulator |
| etiroxate | [no description available] | low | 0 | 0 | aromatic ether | |
| etofamide | [no description available] | low | 0 | 0 | aromatic ether | |
| d 888 | [no description available] | low | 0 | 0 | aromatic ether;
nitrile;
tertiary amino compound | anti-arrhythmia drug;
calcium channel blocker;
vasodilator agent |
| esreboxetine | [no description available] | low | 0 | 0 | aromatic ether | |
| guaethol | [no description available] | low | 0 | 0 | aromatic ether;
phenols;
volatile organic compound | flavouring agent |
| spiramide | [no description available] | low | 0 | 0 | aromatic ether;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound | dopaminergic antagonist;
serotonergic antagonist |
| 5'-nitro-2'-propoxyacetanilide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| suberosin | [no description available] | low | 0 | 0 | aromatic ether;
coumarins | anticoagulant;
plant metabolite |
| 4-methoxyestradiol | [no description available] | low | 0 | 0 | 17beta-hydroxy steroid;
3-hydroxy steroid;
aromatic ether;
phenols | estrogen;
human metabolite;
rat metabolite |
| toltrazuril | [no description available] | low | 0 | 0 | aromatic ether | |
| plafibride | [no description available] | low | 0 | 0 | aromatic ether | |
| cinitapride | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| isoscopoletin | [no description available] | low | 0 | 0 | aromatic ether;
hydroxycoumarin | plant metabolite |
| ethofenprox | [no description available] | low | 0 | 0 | aromatic ether | pyrethroid ether insecticide |
| uk 68798 | [no description available] | low | 0 | 0 | aromatic ether;
sulfonamide;
tertiary amino compound | anti-arrhythmia drug;
potassium channel blocker |
| hp 873 | [no description available] | low | 0 | 0 | 1,2-benzoxazoles;
aromatic ether;
aromatic ketone;
methyl ketone;
monoamine;
organofluorine compound;
piperidines;
tertiary amino compound | dopaminergic antagonist;
second generation antipsychotic;
serotonergic antagonist |
| fenoxypropazine | [no description available] | low | 0 | 0 | aromatic ether | |
| fluphenacur | [no description available] | low | 0 | 0 | aromatic ether;
benzoylurea insecticide;
dichlorobenzene;
N-acylurea;
organofluorine compound | |
| amezinium | [no description available] | low | 0 | 0 | aromatic ether;
primary arylamine;
pyridazinium ion | adrenergic uptake inhibitor;
antihypotensive agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
sympathomimetic agent |
| rubrofusarin | [no description available] | low | 0 | 0 | aromatic ether;
benzochromenone;
phenols;
polyketide | biological pigment;
EC 1.14.18.1 (tyrosinase) inhibitor;
fungal metabolite |
| triasulfuron | [no description available] | low | 0 | 0 | 1,3,5-triazines;
aromatic ether;
N-sulfonylurea;
organochlorine compound | agrochemical;
herbicide |
| dauricine | [no description available] | low | 0 | 0 | aromatic ether;
bisbenzylisoquinoline alkaloid;
isoquinolines;
phenols;
tertiary amino compound | plant metabolite |
| uvaretin | [no description available] | low | 0 | 0 | aromatic ether;
dihydrochalcones;
polyketide;
resorcinol | antineoplastic agent;
plant metabolite |
| fangchinoline | [no description available] | low | 0 | 0 | aromatic ether;
bisbenzylisoquinoline alkaloid;
macrocycle | anti-HIV-1 agent;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
neuroprotective agent;
plant metabolite |
| prochloraz | [no description available] | low | 0 | 0 | amide fungicide;
aromatic ether;
conazole fungicide;
imidazole fungicide;
imidazoles;
trichlorobenzene;
ureas | antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
environmental contaminant;
xenobiotic |
| stictic acid | [no description available] | low | 0 | 0 | aromatic ether | |
| pramoxine hydrochloride | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-methoxybenzylamine | [no description available] | low | 0 | 0 | aralkylamino compound;
aromatic ether;
primary amino compound | |
| xanthurenic acid 8-methyl ether | [no description available] | low | 0 | 0 | aromatic ether;
monohydroxyquinoline;
quinolinemonocarboxylic acid | carcinogenic agent;
metabolite;
mouse metabolite |
| adriamycinol | [no description available] | low | 0 | 0 | aminoglycoside;
anthracycline antibiotic;
aromatic ether;
deoxy hexoside;
p-quinones;
phenols;
polyol;
tetracenequinones | cardiotoxic agent;
drug metabolite |
| difenoconazole | [no description available] | low | 0 | 0 | aromatic ether;
conazole fungicide;
cyclic ketal;
dioxolane;
triazole fungicide;
triazoles | antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
environmental contaminant;
xenobiotic |
| a 8947 | [no description available] | low | 0 | 0 | aromatic ether;
biaryl;
N-sulfonylurea;
pyrazole pesticide;
tetrazoles | EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide |
| thifluzamide | [no description available] | low | 0 | 0 | 1,3-thiazoles;
anilide fungicide;
aromatic amide;
aromatic ether;
dibromobenzene;
organofluorine compound | antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor |
| ethylhydrocupreine | [no description available] | low | 0 | 0 | aromatic ether;
cinchona alkaloid | EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor |
| 7,8-dihydromethysticin | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| 4,5-dimethoxy-2-nitrobenzaldehyde | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| bisphenol f diglycidyl ether | [no description available] | low | 0 | 0 | aromatic ether;
diarylmethane;
epoxide | |
| oryzemate | [no description available] | low | 0 | 0 | 1,2-benzisothiazole;
aromatic ether;
benzothiazole fungicide;
sulfone | antifungal agrochemical;
plant activator |
| bitertanol | [no description available] | low | 0 | 0 | aromatic ether;
biphenyls;
secondary alcohol;
triazoles | |
| fluazifop | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
organofluorine compound;
pyridines | |
| diflufenican | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
pyridinecarboxamide | carotenoid biosynthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic |
| hexafluoron | [no description available] | low | 0 | 0 | aromatic ether;
benzoylurea insecticide;
dichlorobenzene;
N-acylurea;
organochlorine insecticide;
organofluorine insecticide | |
| diethofencarb | [no description available] | low | 0 | 0 | aromatic ether;
carbamate ester;
carbanilate fungicide | antifungal agrochemical |
| pyriproxyfen | [no description available] | low | 0 | 0 | aromatic ether;
pyridines | juvenile hormone mimic |
| methyl 2-(((((4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl)amino)carbonyl)amino)sulfonyl)benzoate | [no description available] | low | 0 | 0 | aromatic ether;
benzoate ester;
diamino-1,3,5-triazine;
methyl ester;
N-sulfonylurea | EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide |
| dpx e9636 | [no description available] | low | 0 | 0 | aromatic ether;
N-sulfonylurea;
pyridines;
pyrimidines;
sulfone | environmental contaminant;
herbicide;
xenobiotic |
| aclonifen | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound;
monochlorobenzenes;
primary amino compound;
substituted aniline | agrochemical;
carotenoid biosynthesis inhibitor;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide |
| cinosulfuron | [no description available] | low | 0 | 0 | aromatic ether | |
| clodinafop-propargyl | [no description available] | low | 0 | 0 | aromatic ether;
carboxylic ester;
organochlorine compound;
organofluorine compound;
propyzamide;
pyridines | agrochemical;
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
herbicide |
| triflusulfuron-methyl | [no description available] | low | 0 | 0 | 1,3,5-triazines;
aromatic ether;
benzoate ester;
methyl ester;
N-sulfonylurea;
organofluorine compound;
tertiary amino compound | agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
proherbicide |
| vestitol | [no description available] | low | 0 | 0 | aromatic ether;
hydroxyisoflavans;
methoxyisoflavan | anti-inflammatory agent;
phytoalexin;
plant metabolite |
| laudanine | [no description available] | low | 0 | 0 | aromatic ether;
benzylisoquinoline alkaloid;
benzyltetrahydroisoquinoline;
phenols;
racemate | |
| cryptopleurine | [no description available] | low | 0 | 0 | alkaloid antibiotic;
alkaloid;
aromatic ether;
organic heteropentacyclic compound | antineoplastic agent;
antiviral agent;
protein synthesis inhibitor |
| 6-hydroxymethylmexiletine | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-hydroxymexiletine | [no description available] | low | 0 | 0 | aromatic ether;
phenols | |
| cloquintocet-mexyl | [no description available] | low | 0 | 0 | aromatic ether;
carboxylic ester;
organochlorine compound;
quinolines | |
| novaluron | [no description available] | low | 0 | 0 | aromatic ether;
benzoylurea insecticide;
monochlorobenzenes;
organofluorine compound | |
| bursehernin | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxoles;
butan-4-olide;
lignan | plant metabolite |
| 2,2',4,4'-tetrabromodiphenyl ether | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound | |
| allocryptopine | [no description available] | low | 0 | 0 | aromatic ether;
cyclic acetal;
cyclic ketone;
dibenzazecine alkaloid;
organic heterotetracyclic compound;
tertiary amino compound | |
| sporidesmin | [no description available] | low | 0 | 0 | aromatic ether;
cyclic ketone;
diketone;
organic disulfide;
organic heteropentacyclic compound;
organochlorine compound;
secondary alcohol;
tertiary alcohol;
tertiary amino compound | mycotoxin;
Wnt signalling activator |
| syringaresinol | [no description available] | low | 0 | 0 | aromatic ether;
furofuran;
lignan;
polyether;
polyphenol | plant metabolite |
| p-methoxy-n-methylphenethylamine | [no description available] | low | 0 | 0 | aromatic ether;
secondary amino compound | metabolite |
| aflatoxin q1 | [no description available] | low | 0 | 0 | aflatoxin;
aromatic ether;
aromatic ketone | carcinogenic agent;
human xenobiotic metabolite |
| u 73122 | [no description available] | low | 0 | 0 | aromatic ether;
aza-steroid;
maleimides | EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor |
| cyfluthrin | [no description available] | low | 0 | 0 | aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound;
organofluorine compound | agrochemical;
pyrethroid ester insecticide |
| norverapamil | [no description available] | low | 0 | 0 | aromatic ether;
nitrile;
polyether;
secondary amino compound | |
| fumitremorgin a | [no description available] | low | 0 | 0 | aromatic ether;
diol;
indole alkaloid;
organic heterohexacyclic compound;
organic peroxide | mycotoxin |
| deguelin | [no description available] | low | 0 | 0 | aromatic ether;
diether;
organic heteropentacyclic compound;
rotenones | angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
mitochondrial NADH:ubiquinone reductase inhibitor;
plant metabolite |
| aristolochic acid ii | [no description available] | low | 0 | 0 | aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound | carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin |
| tephrosin | [no description available] | low | 0 | 0 | aromatic ether;
cyclic ketone;
organic heteropentacyclic compound;
rotenones | antineoplastic agent;
metabolite;
pesticide |
| alpha-hydroxymetoprolol | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(tetradecyloxy)-2-furancarboxylic acid | [no description available] | low | 0 | 0 | aromatic ether;
furoic acid | antineoplastic agent;
apoptosis inducer;
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
PPARalpha agonist |
| tafenoquine | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aminoquinoline;
aromatic ether;
primary amino compound;
secondary amino compound | |
| 5-hydroxymethylomeprazole | [no description available] | low | 0 | 0 | aromatic ether;
benzimidazoles;
pyridines;
sulfoxide | drug metabolite |
| mosapride | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
secondary carboxamide;
substituted aniline;
tertiary amino compound | |
| ym 12617 | [no description available] | low | 0 | 0 | aromatic ether;
secondary amino compound;
sulfonamide | |
| gefitinib | [no description available] | low | 0 | 0 | aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
quinazolines;
secondary amino compound;
tertiary amino compound | antineoplastic agent;
epidermal growth factor receptor antagonist |
| cgp 28392 | [no description available] | low | 0 | 0 | aromatic ether | |
| sodium-binding benzofuran isophthalate | [no description available] | low | 0 | 0 | 1-benzofurans;
aromatic ether;
crown compound;
tetracarboxylic acid | fluorochrome |
| garenoxacin | [no description available] | low | 0 | 0 | aromatic ether;
cyclopropanes;
isoindoles;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone antibiotic | antibacterial drug;
non-steroidal anti-inflammatory drug |
| ay 25545 | [no description available] | low | 0 | 0 | acetate ester;
aromatic ether;
C-glycosyl compound;
naphthoisochromene;
olefinic compound;
phenols;
tertiary amine | antimicrobial agent;
antineoplastic agent;
bacterial metabolite |
| reboxetine | [no description available] | low | 0 | 0 | aromatic ether | |
| b 823-08 | [no description available] | low | 0 | 0 | aromatic ether | |
| cyclazosin | [no description available] | low | 0 | 0 | aromatic amide;
aromatic ether;
furans;
monocarboxylic acid amide;
quinazolines;
quinoxaline derivative | adenosine A2A receptor antagonist |
| ivabradine | [no description available] | low | 0 | 0 | aromatic ether;
benzazepine;
carbobicyclic compound;
tertiary amino compound | cardiotonic drug |
| febuxostat | [no description available] | low | 0 | 0 | 1,3-thiazolemonocarboxylic acid;
aromatic ether;
nitrile | EC 1.17.3.2 (xanthine oxidase) inhibitor |
| marsupsin | [no description available] | low | 0 | 0 | 1-benzofurans;
aromatic ether;
polyphenol | antilipemic drug;
hypoglycemic agent;
metabolite |
| 6,6'-bieckol | [no description available] | low | 0 | 0 | aromatic ether;
oxacycle;
phlorotannin | anti-HIV-1 agent;
metabolite;
radical scavenger |
| xibenolol | [no description available] | low | 0 | 0 | aromatic ether | |
| cicloprolol | [no description available] | low | 0 | 0 | aromatic ether | |
| chs 828 | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(4-methoxyphenoxy)propanoic acid | [no description available] | low | 0 | 0 | aromatic ether;
carboxylic acid | |
| moxifloxacin | [no description available] | low | 0 | 0 | aromatic ether;
cyclopropanes;
fluoroquinolone antibiotic;
pyrrolidinopiperidine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone | antibacterial drug |
| rp 73401 | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
chloropyridine;
monocarboxylic acid amide | anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
phosphodiesterase IV inhibitor |
| 2,2',4,4',5,5'-hexabrominated diphenyl ether | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound | |
| varespladib | [no description available] | low | 0 | 0 | aromatic ether;
benzenes;
dicarboxylic acid monoamide;
indoles;
monocarboxylic acid;
primary carboxamide | anti-inflammatory drug;
antidote;
EC 3.1.1.4 (phospholipase A2) inhibitor |
| birb 796 | [no description available] | low | 0 | 0 | aromatic ether;
morpholines;
naphthalenes;
pyrazoles;
ureas | EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
immunomodulator |
| schizandrin b | [no description available] | low | 0 | 0 | aromatic ether;
cyclic acetal;
organic heterotetracyclic compound;
oxacycle;
tannin | anti-asthmatic agent;
anti-inflammatory agent;
antilipemic drug;
antioxidant;
apoptosis inhibitor;
hepatoprotective agent;
nephroprotective agent;
neuroprotective agent;
plant metabolite |
| s 23121 | [no description available] | low | 0 | 0 | aromatic ether;
dicarboximide;
monochlorobenzenes;
monofluorobenzenes;
pyrroline;
terminal acetylenic compound | |
| acrovestone | [no description available] | low | 0 | 0 | acetophenones;
aromatic ether;
olefinic compound;
polyphenol | antioxidant;
EC 1.14.18.1 (tyrosinase) inhibitor;
plant metabolite |
| corytuberine | [no description available] | low | 0 | 0 | aporphine alkaloid;
aromatic ether;
organic heterotetracyclic compound;
polyphenol;
tertiary amino compound | plant metabolite |
| actinodaphine | [no description available] | low | 0 | 0 | aporphine alkaloid;
aromatic ether;
organic heteropentacyclic compound;
phenols;
secondary amino compound | antibacterial agent;
antifungal agent;
antineoplastic agent;
apoptosis inducer;
plant metabolite;
platelet aggregation inhibitor;
topoisomerase inhibitor |
| isohomovanillic acid | [no description available] | low | 0 | 0 | aromatic ether;
phenols;
phenylacetic acids | metabolite |
| 3,5-diiodothyropropionic acid | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
organoiodine compound;
phenols | |
| 7,8-dihydro-5,6-dehydrokawain | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| 4-amino-2-methoxypyrimidine | [no description available] | low | 0 | 0 | aminopyrimidine;
aromatic ether;
methylcytosine | metabolite |
| aristolochic acid D | [no description available] | low | 0 | 0 | aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound | carcinogenic agent;
metabolite;
nephrotoxin;
toxin |
| myricanone | [no description available] | low | 0 | 0 | aromatic ether;
cyclic ketone;
diarylheptanoid;
methoxybenzenes;
phenols | antineoplastic agent;
plant metabolite |
| pannarin | [no description available] | low | 0 | 0 | aldehyde;
aromatic ether;
depsidones;
organic heterotricyclic compound;
organochlorine compound;
phenols | antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
lichen metabolite |
| aminopotentidine | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
guanidines;
nitrile;
piperidines;
substituted aniline | H2-receptor antagonist |
| aristolochic acid c | [no description available] | low | 0 | 0 | aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound | carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin |
| pluviatolide | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxoles;
butan-4-olide;
lignan;
phenols | plant metabolite |
| erysodine | [no description available] | low | 0 | 0 | aromatic ether;
diether;
Erythrina alkaloid;
organic heterotetracyclic compound;
phenols | antiparasitic agent;
nicotinic antagonist;
phytogenic insecticide |
| erlotinib | [no description available] | low | 0 | 0 | aromatic ether;
quinazolines;
secondary amino compound;
terminal acetylenic compound | antineoplastic agent;
epidermal growth factor receptor antagonist;
protein kinase inhibitor |
| rubrofusarin B | [no description available] | low | 0 | 0 | aromatic ether;
benzochromenone;
naphtho-gamma-pyrone;
phenols;
polyketide | Aspergillus metabolite |
| ly 293111 | [no description available] | low | 0 | 0 | aromatic ether | |
| enrasentan | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxoles;
indanes;
monocarboxylic acid;
monomethoxybenzene;
primary alcohol | antihypertensive agent;
endothelin receptor antagonist |
| quizalofop | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
organochlorine compound;
quinoxaline derivative | |
| cyhalofop-butyl | [no description available] | low | 0 | 0 | aromatic ether | |
| cyperin | [no description available] | low | 0 | 0 | aromatic ether | |
| aflatoxin b1 | [no description available] | low | 0 | 0 | aflatoxin;
aromatic ether;
aromatic ketone | carcinogenic agent;
human metabolite |
| etravirine | [no description available] | low | 0 | 0 | aminopyrimidine;
aromatic ether;
dinitrile;
organobromine compound | antiviral agent;
HIV-1 reverse transcriptase inhibitor |
| 5-o-methyllicoricidin | [no description available] | low | 0 | 0 | aromatic ether;
hydroxyisoflavans;
methoxyisoflavan | antibacterial agent;
plant metabolite |
| pronuciferine | [no description available] | low | 0 | 0 | aromatic ether;
cyclic ketone;
isoquinoline alkaloid;
isoquinolines;
organic heterotetracyclic compound | plant metabolite |
| dronedarone | [no description available] | low | 0 | 0 | 1-benzofurans;
aromatic ether;
aromatic ketone;
sulfonamide;
tertiary amino compound | anti-arrhythmia drug;
environmental contaminant;
xenobiotic |
| famoxadone | [no description available] | low | 0 | 0 | aromatic ether;
carbohydrazide;
oxazolidinone | |
| cimicoxib | [no description available] | low | 0 | 0 | aromatic ether;
imidazoles;
organochlorine compound;
organofluorine compound;
sulfonamide | cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug |
| sorafenib | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
phenylureas;
pyridinecarboxamide | angiogenesis inhibitor;
anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
ferroptosis inducer;
tyrosine kinase inhibitor |
| dabuzalgron | [no description available] | low | 0 | 0 | aromatic ether;
imidazoles;
monochlorobenzenes;
sulfonamide | alpha-adrenergic agonist |
| fonsecin | [no description available] | low | 0 | 0 | aromatic ether;
cyclic hemiketal;
heptaketide;
naphtho-gamma-pyrone;
phenols | Aspergillus metabolite;
marine metabolite |
| lasofoxifene | [no description available] | low | 0 | 0 | aromatic ether;
N-alkylpyrrolidine;
naphthols;
tetralins | antineoplastic agent;
bone density conservation agent;
cardioprotective agent;
estrogen receptor agonist;
estrogen receptor antagonist |
| (+-)-Dihydromethysticin | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| 2-[2-[2-(2-aminophenoxy)ethoxy]ethoxy]aniline | [no description available] | low | 0 | 0 | aromatic ether;
substituted aniline | |
| chondocurine (1beta)-(+-)-isomer | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-methyl-4-prop-2-enoxy-2-pyrimidinone | [no description available] | low | 0 | 0 | aromatic ether;
pyrimidone | |
| noscapine | [no description available] | low | 0 | 0 | aromatic ether;
benzylisoquinoline alkaloid;
cyclic acetal;
isobenzofuranone;
organic heterobicyclic compound;
organic heterotricyclic compound;
tertiary amino compound | antineoplastic agent;
antitussive;
apoptosis inducer;
plant metabolite |
| 4-[4-(3-methyl-4-nitrophenoxy)butoxy]benzonitrile | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| lariciresinol | [no description available] | low | 0 | 0 | aromatic ether;
lignan;
oxolanes;
phenols;
primary alcohol | antifungal agent;
plant metabolite |
| tryptoquivaline | [no description available] | low | 0 | 0 | aromatic ether;
indole alkaloid;
organic heteropentacyclic compound | breast cancer resistance protein inhibitor;
mycotoxin |
| 2-methoxyestrone | [no description available] | low | 0 | 0 | 17-oxo steroid;
3-hydroxy steroid;
alicyclic ketone;
aromatic ether;
phenolic steroid;
phenols | human metabolite;
mouse metabolite |
| win 54954 | [no description available] | low | 0 | 0 | aromatic ether | |
| silychristin | [no description available] | low | 0 | 0 | 1-benzofurans;
aromatic ether;
flavonolignan;
polyphenol;
secondary alpha-hydroxy ketone | lipoxygenase inhibitor;
metabolite;
prostaglandin antagonist;
radical scavenger |
| cleomiscosin a | [no description available] | low | 0 | 0 | aromatic ether;
delta-lactone;
organic heterotricyclic compound;
phenols;
primary alcohol | anti-inflammatory agent;
metabolite |
| bispyribac | [no description available] | low | 0 | 0 | aromatic ether;
benzoic acids;
monocarboxylic acid;
pyrimidines | herbicide |
| petunidin-3-glucoside | [no description available] | low | 0 | 0 | anthocyanin cation;
aromatic ether;
beta-D-glucoside | antioxidant;
metabolite |
| malvidin-3-glucoside | [no description available] | low | 0 | 0 | anthocyanin cation;
aromatic ether;
beta-D-glucoside | metabolite |
| dioncophylline c | [no description available] | low | 0 | 0 | aromatic ether;
biaryl;
isoquinoline alkaloid;
isoquinolines;
methoxynaphthalene;
methylnaphthalenes;
naphthols | antimalarial;
antiplasmodial drug;
metabolite |
| stigmatellin | [no description available] | low | 0 | 0 | aromatic ether;
chromones;
olefinic compound;
phenols | bacterial metabolite;
quinol oxidation site inhibitor |
| roflumilast | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
chloropyridine;
cyclopropanes;
organofluorine compound | anti-asthmatic drug;
phosphodiesterase IV inhibitor |
| teniposide | [no description available] | low | 0 | 0 | aromatic ether;
beta-D-glucoside;
cyclic acetal;
furonaphthodioxole;
gamma-lactone;
monosaccharide derivative;
phenols;
thiophenes | antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor |
| prinomastat | [no description available] | low | 0 | 0 | aromatic ether;
hydroxamic acid;
pyridines;
sulfonamide;
thiomorpholines | antineoplastic agent;
EC 3.4.24.35 (gelatinase B) inhibitor;
matrix metalloproteinase inhibitor |
| posaconazole | [no description available] | low | 0 | 0 | aromatic ether;
conazole antifungal drug;
N-arylpiperazine;
organofluorine compound;
oxolanes;
triazole antifungal drug;
triazoles | trypanocidal drug |
| gancaonin I | [no description available] | low | 0 | 0 | 1-benzofurans;
aromatic ether;
resorcinols | antibacterial agent;
plant metabolite |
| glycyrin | [no description available] | low | 0 | 0 | aromatic ether;
coumarins;
hydroxyisoflavans | antibacterial agent;
metabolite;
plant metabolite |
| glyasperin D | [no description available] | low | 0 | 0 | aromatic ether;
hydroxyisoflavans;
methoxyisoflavan | plant metabolite |
| licoricidin | [no description available] | low | 0 | 0 | aromatic ether;
hydroxyisoflavans;
methoxyisoflavan | antibacterial agent;
plant metabolite |
| egonol | [no description available] | low | 0 | 0 | 1-benzofurans;
aromatic ether;
benzodioxoles;
primary alcohol | plant metabolite |
| N-ethylharmine | [no description available] | low | 0 | 0 | aromatic ether;
beta-carbolines;
semisynthetic derivative | anti-HIV agent |
| pf 1163a | [no description available] | low | 0 | 0 | aromatic ether;
lactam;
macrolide antibiotic;
secondary alcohol | antifungal agent;
Penicillium metabolite |
| pf 1163b | [no description available] | low | 0 | 0 | aromatic ether;
lactam;
macrolide antibiotic | antifungal agent;
Penicillium metabolite |
| licocoumarone | [no description available] | low | 0 | 0 | 1-benzofurans;
aromatic ether;
resorcinols | antibacterial agent;
apoptosis inducer;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite |
| 4-(4-chloro-2-methylphenoxy)-n-hydroxybutanamide | [no description available] | low | 0 | 0 | aromatic ether | |
| LSM-22807 | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[2-(3-methylphenoxy)ethyl]-1H-1,2,4-triazole-5-carboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| piperlactam s | [no description available] | low | 0 | 0 | alkaloid;
aromatic ether;
gamma-lactam;
organic heterotetracyclic compound;
phenols | anti-inflammatory agent;
antioxidant;
plant metabolite |
| 5,5-dioxo-1-(4-phenoxyphenyl)-3a,4,6,6a-tetrahydro-3H-thieno[3,4-b]pyrrol-2-one | [no description available] | low | 0 | 0 | aromatic ether | |
| antofine | [no description available] | low | 0 | 0 | alkaloid antibiotic;
alkaloid;
aromatic ether;
organic heteropentacyclic compound | angiogenesis inhibitor;
anti-inflammatory agent;
antimicrobial agent;
antineoplastic agent;
antiviral agent;
phytotoxin;
plant metabolite |
| xanthohumol | [no description available] | low | 0 | 0 | aromatic ether;
chalcones;
polyphenol | anti-HIV-1 agent;
antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor;
metabolite |
| 2-phenoxy-N-(2-pyridinyl)butanamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 6-amino-4-(2-ethoxyphenyl)-3-propyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | [no description available] | low | 0 | 0 | aromatic ether;
pyranopyrazole | |
| N-[4-[4-[[1-oxo-2-(1-pyrrolidinyl)ethyl]amino]phenoxy]phenyl]-2-(1-pyrrolidinyl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(3,4-diethoxyphenyl)-5-(2-furanyl)-1,3,4-oxadiazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[[5-(phenoxymethyl)-4-(2-phenylethyl)-1,2,4-triazol-3-yl]thio]acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(8-methyl-2,5,11,14-tetraoxa-8-azabicyclo[13.4.0]nonadeca-1(15),16,18-trien-17-yl)ethanol | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-[2-(3-phenoxypropyl)-5-tetrazolyl]pyridine | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-cyclohexyl-5-(2-phenoxyethylthio)tetrazole | [no description available] | low | 0 | 0 | aromatic ether | |
| N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-[[5-[(3-methylphenoxy)methyl]-1,3,4-oxadiazol-2-yl]thio]acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 6-amino-4-[3-ethoxy-4-[2-(4-morpholinyl)ethoxy]phenyl]-3-ethyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | [no description available] | low | 0 | 0 | aromatic ether;
pyranopyrazole | |
| 2-[[5-[(2,3-dimethylphenoxy)methyl]-4-methyl-1,2,4-triazol-3-yl]thio]-1-thiophen-2-ylethanone | [no description available] | low | 0 | 0 | aromatic ether | |
| (1-methyl-2-imidazolyl)-(4-phenylmethoxyphenyl)methanol | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(3-butoxyphenyl)-1,3,4-thiadiazol-2-amine | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-(2-ethoxy-6-methyl-3-pyridinyl)-5-(2-pyridinyl)-1,2,4-oxadiazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 6-(3,4,5-triethoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole | [no description available] | low | 0 | 0 | aromatic ether;
triazolothiadiazole | |
| 4-(1-benzotriazolyl)-5-(2-methoxyphenoxy)benzene-1,2-dicarbonitrile | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-cyclohexyl-3-[(3-methylphenoxy)methyl]-1H-1,2,4-triazole-5-thione | [no description available] | low | 0 | 0 | aromatic ether | |
| 7-ethoxy-9-nitro-5H-benzo[b][1,4]benzoxazepin-6-one | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-[4-(2-quinoxalinyl)phenoxy]benzene-1,2-dicarbonitrile | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(4-amino-1,2,5-oxadiazol-3-yl)-5-(phenoxymethyl)-4-triazolecarboxylic acid ethyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(4-ethylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(4-chloro-3-methylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-[(4-ethylphenoxy)methyl]-N-(2-pyridinylmethyl)-2-furancarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 7-methoxy-3,5-dimethyl-2-thiazolo[4,5-d]pyrimidinethione | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[4-(4-ethylphenyl)-2-thiazolyl]carbamic acid phenyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(2-bromo-4-methylphenoxy)-N-(2-pyridinylmethyl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[[3-(4-chlorophenoxy)phenyl]methyl]-4-ethylpiperazine | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-methoxy-4-[(4-methyl-1,4-diazepan-1-yl)methyl]-6-nitrophenol | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 4-[[4-(ethylamino)-6-(methylthio)-1,3,5-triazin-2-yl]oxy]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-ethyl-3-[[4-(2-methylpropoxy)phenyl]methylthio]-1H-1,2,4-triazole | [no description available] | low | 0 | 0 | aromatic ether | |
| [4-[(2-fluorophenyl)methoxy]phenyl]-(1-pyrrolidinyl)methanethione | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-[(2-chlorophenoxy)methyl]-3-pyridin-4-yl-1,2,4-oxadiazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(4-phenylmethoxyphenyl)thiadiazole | [no description available] | low | 0 | 0 | aromatic ether | |
| N-methyl-2-[[4-methyl-5-[(4-nitrophenoxy)methyl]-1,2,4-triazol-3-yl]thio]acetamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 2-[[5-(4-ethoxyphenyl)-1,3,4-oxadiazol-2-yl]thio]-1-(4-morpholinyl)ethanone | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(3-pyridinyloxy)benzene-1,2-dicarbonitrile | [no description available] | low | 0 | 0 | aromatic ether | |
| N-tert-butyl-2-(4-chloro-3-methylphenoxy)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(2-furanylmethyl)-3-(4-phenoxyphenyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(2-methylpropyl)-3-(4-phenoxyphenyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-cyclopentyl-3-(4-phenoxyphenyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-[(4-ethoxyphenoxy)methyl]-N-(3-pyridinyl)-2-furancarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(2,3-dimethylphenoxy)-N-pyridin-4-ylacetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-[(2-chlorophenoxy)methyl]-N-(2-thiazolyl)-2-furancarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-2-furancarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| N-(4,5-dihydrothiazol-2-yl)-2-(2-methylphenoxy)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(2-fluorophenoxy)-1-methyl-3-nitro-1,2,4-triazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-methyl-5-(1-naphthalenyloxy)-4-nitroimidazole | [no description available] | low | 0 | 0 | aromatic ether | |
| curcumin | [no description available] | low | 0 | 0 | aromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol | anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger |
| 1-(3,4-dimethoxyphenyl)-3-(2-methoxy-5-nitrophenyl)urea | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 1-cyclopentyl-3-(2-phenoxyphenyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| N-(1-ethyl-2-benzimidazolyl)-5-[(4-methyl-2-nitrophenoxy)methyl]-2-furancarboxamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 2-chloro-12-(4-methoxyphenyl)sulfonylquinoxalino[2,3-b][1,4]benzoxazine | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(3-methoxy-5-nitrophenyl)-3-(4-methylphenyl)urea | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 2-(2-bromo-4-chlorophenoxy)-N-cyclohexyl-N-methylacetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-furanyl-[4-(4-phenoxyphenyl)sulfonyl-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(2-methoxyphenoxy)-N-(3-pyridinyl)benzenesulfonamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(3-chlorophenyl)-3-(2-phenoxyphenyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[3-[2-(1-azepanyl)-4,5-dicyanophenoxy]phenyl]acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2,5-dimethoxy-N-(4-phenoxyphenyl)benzenesulfonamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-[[4-(dimethylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]oxy]benzoic acid methyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-5-methyl-3-phenyl-4-isoxazolecarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[4-[[4-(2-chloro-6-nitrophenoxy)phenyl]methoxy]phenyl]ethanone | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[4-[[2-(4-hydroxyphenyl)-1,3-dioxo-5-isoindolyl]oxy]phenyl]-2,2-dimethylpropanamide | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[[4-(4-chlorophenoxy)anilino]-sulfanylidenemethyl]benzamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(4-fluorophenoxy)-N-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]-N-propan-2-ylbenzenesulfonamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(4-tert-butylphenoxy)-5-methoxy-2-phenylpyrimidine | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-phenoxy-2-phenyl-5-pyrimidinecarboxylic acid ethyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| Src Inhibitor-1 | [no description available] | low | 0 | 0 | aromatic ether;
polyether;
quinazolines;
secondary amino compound | EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor |
| N-[2,5-dioxo-6-(4-phenoxyphenyl)-3-pyrano[3,2-c]pyridinyl]benzamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(4-chlorophenoxy)-4-(dimethylamino)-3-pyridinecarbonitrile | [no description available] | low | 0 | 0 | aromatic ether | |
| 6-methyl-5-[2-(2-methylphenoxy)ethyl]-2-sulfanylidene-1H-pyrimidin-4-one | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(4-chlorophenoxy)-1-(4-morpholinyl)-1-butanone | [no description available] | low | 0 | 0 | aromatic ether | |
| N4-ethyl-6-[2-(4-methylphenoxy)ethylthio]-N2-propan-2-yl-1,3,5-triazine-2,4-diamine | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(phenylmethyl)-3-[2-(4-propoxyphenyl)ethyl]-1H-1,2,4-triazole-5-thione | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[[1-oxo-3-(4-propan-2-yloxyphenyl)propyl]amino]-3-(phenylmethyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[3-(3-methylphenoxy)-5-nitrophenyl]-2-(3-nitro-1,2,4-triazol-1-yl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| N-bis(2-fluorophenoxy)phosphoryl-3,4-dimethylaniline | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[[4-(2-ethoxyanilino)-6-(4-ethoxyanilino)-2-pyrimidinyl]methylidene]propanedinitrile | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-methyl-3-[(4-pentoxyphenyl)methylthio]-1H-1,2,4-triazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 4,5-dichloro-1-[2-(4-chlorophenoxy)ethyl]imidazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-butyl-3-(4-phenoxyphenyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| N-(3-cyano-2-thiophenyl)-2-[4-(1,3,4-oxadiazol-2-yl)phenoxy]acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(2-bromophenyl)-5-[(2-chlorophenoxy)methyl]-1,3,4-oxadiazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(4-ethoxyphenyl)-N-(3,4,5,6-tetrahydro-2H-azepin-7-yl)-1,3,4-oxadiazol-2-amine | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(4-chloro-2-methylphenoxy)-1-(4-morpholinyl)-1-butanone | [no description available] | low | 0 | 0 | aromatic ether | |
| N9-(4-butoxyphenyl)-6,8,10-triazaspiro[4.5]deca-6,9-diene-7,9-diamine | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[2-(4-chlorophenoxy)ethylthio]pyrimidine | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(3-phenoxypropyl)-3-(3-pyridinyl)-1,2,4-oxadiazole | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[(3-ethoxy-2-prop-2-enoxyphenyl)methyl]-2-thiazolamine | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(2-bromophenoxy)-N-(2-pyridinylmethyl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-[2-[(4-chlorophenyl)thio]ethoxy]-3-ethoxybenzaldehyde | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(3-fluorophenyl)-4-(4-hydroxy-3-methoxy-5-nitrophenyl)-4H-pyridine-3,5-dicarboxylic acid diethyl ester | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 5-(2-ethoxyphenyl)-3H-1,3,4-oxadiazole-2-thione | [no description available] | low | 0 | 0 | aromatic ether | |
| N-tert-butyl-4-(2-fluorophenoxy)-1-butanamine | [no description available] | low | 0 | 0 | aromatic ether | |
| N-butyl-4-phenoxy-1-butanamine | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[3-[[diethylamino(sulfanylidene)methyl]thio]-1-oxopropyl]carbamic acid (4-methylphenyl) ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 1,3-dimethyl-5-[[2-[2-(4-nitrophenoxy)ethoxy]phenyl]methylidene]-1,3-diazinane-2,4,6-trione | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 4-[2-[2-(4-bromo-2-chlorophenoxy)ethoxy]ethyl]morpholine | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[2-(3-ethylphenoxy)ethyl]propanedioic acid diethyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 2,3-dihydro-1,4-dioxin-5-carboxylic acid [2-[4-[4-(2-methylbutan-2-yl)phenoxy]anilino]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[3-(2-bromo-4-chlorophenoxy)propyl]-4-methylpiperidine | [no description available] | low | 0 | 0 | aromatic ether | |
| N4-(2-methoxyphenyl)benzene-1,4-diamine | [no description available] | low | 0 | 0 | aromatic ether;
substituted aniline | |
| 4-(1H-benzimidazol-2-ylthio)butanoic acid [2-oxo-2-(4-phenoxyanilino)ethyl] ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-phenoxybenzoic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[2,5-dimethyl-1-(phenylmethyl)-3-pyrrolyl]-2-[4-(1,3,4-oxadiazol-2-yl)phenoxy]ethanone | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[6-amino-1-(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]-2-(2-methylphenoxy)-N-(2-methylpropyl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-[[6-[(2-methyl-5-thieno[2,3-e][1,3]benzothiazolyl)oxy]-3-pyridinyl]sulfonyl]morpholine | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(3-fluorophenoxy)-8-nitroisoquinoline | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[4-(2-prop-2-enylphenoxy)butyl]pyrrolidine | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(2,4-dibromophenoxy)-N-[oxo-(propan-2-ylamino)methyl]acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-phenoxyphenyl 4-hydroxypiperidine-1-carboxylate | [no description available] | low | 0 | 0 | aromatic ether | |
| N'-benzoyl-5-(3,5-dichlorophenoxy)-2-furancarbohydrazide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[2-[(4-chlorophenoxy)methyl]-4-thiazolyl]ethanone | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(benzyloxy)-2-(hydroxymethyl)-1,4-dihydropyridin-4-one | [no description available] | low | 0 | 0 | aromatic ether | |
| N5-(2-chloro-6-phenoxybenzyl)-1H-1,2,4-triazole-3,5-diamine | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[(2-chloro-6-phenoxyphenyl)methyl]benzenesulfonamide | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[5-(tert-butyl)-3-isoxazolyl]-N'-[2-(trifluoromethoxy)phenyl]urea | [no description available] | low | 0 | 0 | aromatic ether | |
| 6-(4-methoxyphenoxy)-2-imidazo[1,2-b]pyridazinecarboxylic acid ethyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-fluoro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]acetamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 2-amino-4-(4,5-dimethoxy-2-nitrophenyl)-7,7-dimethyl-5-oxo-6,8-dihydro-4H-1-benzopyran-3-carbonitrile | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 2,4-dichloro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]benzamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 1-anilino-3-[4-(3-anilino-2-hydroxypropoxy)phenoxy]-2-propanol | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[4-(3-ethoxyphenoxy)butyl]imidazole | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-2-oxolanecarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[[2-(2,4-difluorophenoxy)-1-oxopropyl]amino]-3-(2-oxolanylmethyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[[(5-bromo-6-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]-2-(2-chlorophenoxy)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[(4-chlorophenyl)sulfonyl-methylamino]-N-(4-methoxy-2-nitrophenyl)acetamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 4-oxido-3-(4-phenoxyphenyl)-4a,5,6,7,8,8a-hexahydroquinoxalin-1-ium 1-oxide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(2-fluorophenyl)-3-(4-methoxy-2-nitrophenyl)urea | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 2-[[5-[(2-fluorophenoxy)methyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-N-[(2-furanylmethylamino)-oxomethyl]acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| cyclopropanecarboxylic acid [2-oxo-2-(4-phenoxyanilino)ethyl] ester | [no description available] | low | 0 | 0 | aromatic ether | |
| toremifene | [no description available] | low | 0 | 0 | aromatic ether;
organochlorine compound;
tertiary amine | antineoplastic agent;
bone density conservation agent;
estrogen antagonist;
estrogen receptor modulator |
| dieckol | [no description available] | low | 0 | 0 | aromatic ether;
oxacycle;
phlorotannin | anticoagulant;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
hepatoprotective agent;
metabolite;
radical scavenger |
| 2-[(2-ethoxyphenoxy)-phenylmethyl]morpholine | [no description available] | low | 0 | 0 | aromatic ether | |
| naproxol | [no description available] | low | 0 | 0 | aromatic ether | antipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| tamoxifen n-oxide | [no description available] | low | 0 | 0 | aromatic ether;
tertiary amine oxide | anti-estrogen;
metabolite |
| diafenthiuron | [no description available] | low | 0 | 0 | aromatic ether;
thiourea acaricide;
thiourea insecticide | oxidative phosphorylation inhibitor;
proinsecticide |
| ospemifene | [no description available] | low | 0 | 0 | aromatic ether;
organochlorine compound;
primary alcohol | anti-inflammatory agent;
antineoplastic agent;
estrogen receptor modulator |
| tandutinib | [no description available] | low | 0 | 0 | aromatic ether;
N-arylpiperazine;
N-carbamoylpiperazine;
phenylureas;
piperidines;
quinazolines;
tertiary amino compound | antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| zd 6474 | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound;
organofluorine compound;
piperidines;
quinazolines;
secondary amine | antineoplastic agent;
tyrosine kinase inhibitor |
| adefovir | [no description available] | low | 0 | 0 | aromatic ether;
aromatic ketone;
biaryl;
cyclic ketone;
naphtho-gamma-pyrone;
organooxygen heterocyclic antibiotic;
polyphenol | antimalarial;
Aspergillus metabolite;
marine metabolite |
| 3-chloro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]benzamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| N-(2-hydroxyethyl)-4-[2-nitro-4-(trifluoromethyl)phenoxy]benzamide | [no description available] | low | 0 | 0 | aromatic ether | |
| N'-[2-[(4-amino-5-cyano-2-pyrimidinyl)thio]-1-oxoethyl]-2-(4-methylphenoxy)acetohydrazide | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[(2-methyl-4-thiazolyl)methyl]-4-phenoxybenzenesulfonamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 6-amino-4-(2-ethoxy-4-hydroxyphenyl)-3-propyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | [no description available] | low | 0 | 0 | aromatic ether;
pyranopyrazole | |
| 1-[(2-ethoxyphenyl)methyl]-3-thiophen-2-ylurea | [no description available] | low | 0 | 0 | aromatic ether | |
| quinoxyfen | [no description available] | low | 0 | 0 | aromatic ether;
monofluorobenzenes;
organochlorine compound;
quinolines | antifungal agrochemical |
| nafadotride | [no description available] | low | 0 | 0 | aromatic ether;
naphthalenecarboxamide;
nitrile;
pyrrolidines;
tertiary amino compound | dopaminergic antagonist |
| 1-(1-naphthalenyl)-3-[[2-(2-nitrophenoxy)-1-oxoethyl]amino]urea | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 2-methyl-1,3-bis(phenylmethoxy)benzene | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethoxyphenoxysulfonyl)urea | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-[(4-ethylphenoxy)methyl]-4-(6-methylheptan-2-yl)-1H-1,2,4-triazole-5-thione | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-chloro-N-(2-methyl-6-oxo-5H-benzo[b][1,4]benzoxazepin-8-yl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(benzenesulfonyl)-4-(2,6-dimethylphenoxy)-2-phenylpyrimidine | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(2-methylphenoxy)-6-phenylfuro[2,3-d]pyrimidine | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[4-(2-chlorophenoxy)butyl]imidazole | [no description available] | low | 0 | 0 | aromatic ether;
imidazoles;
monochlorobenzenes | |
| N-(2-chlorophenyl)-4-[[(2-methoxy-4-nitroanilino)-sulfanylidenemethyl]hydrazo]-4-oxobutanamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| N-(2-methoxy-4-nitrophenyl)-2-[(1-methyl-2-imidazolyl)thio]acetamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| N-[4-(phenoxymethyl)-2-thiazolyl]-1-adamantanecarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| hydroxypioglitazone | [no description available] | low | 0 | 0 | aromatic ether;
pyridines;
thiazolidinediones | human xenobiotic metabolite |
| sc 560 | [no description available] | low | 0 | 0 | aromatic ether;
monochlorobenzenes;
organofluorine compound;
pyrazoles | angiogenesis modulating agent;
antineoplastic agent;
apoptosis inducer;
cyclooxygenase 1 inhibitor;
non-steroidal anti-inflammatory drug |
| sc-19220 | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-methyl-4-(3-phenoxyphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-6-carboxylic acid ethyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 8-[4-(4-fluorophenoxy)-3-nitrophenyl]-7-(2-hydroxyethyl)-3-(phenylmethyl)purine-2,6-dione | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-phenoxybenzoic acid [2-oxo-2-(propan-2-ylamino)ethyl] ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(4-bromophenoxy)-N'-[2-[(4-methyl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]acetohydrazide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(2-methoxyanilino)-2-(2-phenylmethoxyphenyl)acetonitrile | [no description available] | low | 0 | 0 | aromatic ether;
substituted aniline | |
| N-(4-phenoxyphenyl)-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(3,4-dimethoxyphenyl)-3-(2-furanylmethyl)-4-imino-5H-[1]benzopyrano[2,3-d]pyrimidin-8-ol | [no description available] | low | 0 | 0 | aromatic ether | |
| 3,3-dimethyl-1,5-dinitro-6-phenoxy-3-azoniabicyclo[3.3.1]non-6-ene | [no description available] | low | 0 | 0 | aromatic ether | |
| fraxin | [no description available] | low | 0 | 0 | aromatic ether;
beta-D-glucoside;
hydroxycoumarin | anti-inflammatory agent;
hepatoprotective agent;
plant metabolite |
| fraxetin | [no description available] | low | 0 | 0 | aromatic ether;
hydroxycoumarin | anti-inflammatory agent;
antibacterial agent;
antimicrobial agent;
antioxidant;
apoptosis inducer;
apoptosis inhibitor;
Arabidopsis thaliana metabolite;
hepatoprotective agent;
hypoglycemic agent |
| 5,6-dehydrokawain | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| jtk-303 | [no description available] | low | 0 | 0 | aromatic ether;
monochlorobenzenes;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone | HIV-1 integrase inhibitor |
| coniferin | [no description available] | low | 0 | 0 | aromatic ether;
cinnamyl alcohol beta-D-glucoside;
monosaccharide derivative | plant metabolite |
| daphnoretin | [no description available] | low | 0 | 0 | aromatic ether;
hydroxycoumarin | antineoplastic agent;
antiviral agent;
metabolite |
| kavain | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| methysticin | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| yangonin | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| hinokiflavone | [no description available] | low | 0 | 0 | aromatic ether;
biflavonoid;
hydroxyflavone | antineoplastic agent;
metabolite;
neuroprotective agent |
| gentiacaulein | [no description available] | low | 0 | 0 | aromatic ether;
polyphenol;
xanthones | plant metabolite |
| gentisin | [no description available] | low | 0 | 0 | aromatic ether;
polyphenol;
xanthones | plant metabolite |
| isogentisin | [no description available] | low | 0 | 0 | aromatic ether;
polyphenol;
xanthones | EC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite |
| mangostin | [no description available] | low | 0 | 0 | aromatic ether;
phenols;
xanthones | antimicrobial agent;
antineoplastic agent;
antioxidant;
plant metabolite |
| 1,8-dihydroxy-3,7-dimethoxyxanthone | [no description available] | low | 0 | 0 | aromatic ether;
polyphenol;
xanthones | plant metabolite |
| swerchirin | [no description available] | low | 0 | 0 | aromatic ether;
phenols;
xanthones | hypoglycemic agent;
metabolite |
| 1,2,8-trihydroxy-6-methoxyxanthone | [no description available] | low | 0 | 0 | aromatic ether;
polyphenol;
xanthones | antioxidant;
plant metabolite |
| wedelolactone | [no description available] | low | 0 | 0 | aromatic ether;
coumestans;
delta-lactone;
polyphenol | antineoplastic agent;
apoptosis inducer;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
hepatoprotective agent;
metabolite |
| cyhalothrin | [no description available] | low | 0 | 0 | aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound;
organofluorine compound | agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide |
| sofalcone | [no description available] | low | 0 | 0 | aromatic ether;
chalcones;
monocarboxylic acid | anti-ulcer drug;
antibacterial agent;
gastrointestinal drug;
plant metabolite |
| neticonazole | [no description available] | low | 0 | 0 | aromatic ether;
benzenes;
conazole antifungal drug;
enamine;
imidazole antifungal drug;
imidazoles;
methyl sulfide | antifungal drug;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor |
| pibutidine | [no description available] | low | 0 | 0 | aromatic ether;
cyclobutenones;
olefinic compound;
piperidines;
primary amino compound;
pyridines;
secondary amino compound | anti-ulcer drug;
H2-receptor antagonist |
| purmorphamine | [no description available] | low | 0 | 0 | aromatic ether;
morpholines;
purines;
secondary amino compound | osteogenesis regulator;
SMO receptor agonist |
| 8-(2-chlorophenyl)-3-(4-ethoxyphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile | [no description available] | low | 0 | 0 | aromatic ether | |
| ro 41-5253 | [no description available] | low | 0 | 0 | aromatic ether;
benzoic acids;
sulfone;
thiochromane | apoptosis inducer;
retinoic acid receptor alpha antagonist |
| glycycoumarin | [no description available] | low | 0 | 0 | aromatic ether;
coumarins;
resorcinols | antispasmodic drug;
plant metabolite |
| isoginkgetin | [no description available] | low | 0 | 0 | aromatic ether;
biflavonoid | antineoplastic agent;
EC 3.4.24.35 (gelatinase B) inhibitor;
plant metabolite |
| neoglycyrol | [no description available] | low | 0 | 0 | aromatic ether;
coumestans;
delta-lactone;
polyphenol | antineoplastic agent;
plant metabolite |
| rhamnazin | [no description available] | low | 0 | 0 | aromatic ether;
dimethoxyflavone;
phenols;
trihydroxyflavone | antineoplastic agent;
plant metabolite |
| bosutinib | [no description available] | low | 0 | 0 | aminoquinoline;
aromatic ether;
dichlorobenzene;
N-methylpiperazine;
nitrile;
tertiary amino compound | antineoplastic agent;
tyrosine kinase inhibitor |
| bw b70c | [no description available] | low | 0 | 0 | aromatic ether;
hydroxamic acid;
organofluorine compound;
ureas | EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor |
| lichexanthone | [no description available] | low | 0 | 0 | aromatic ether;
phenols;
xanthones | plant metabolite |
| alternariol monomethyl ether | [no description available] | low | 0 | 0 | aromatic ether;
benzochromenone | antifungal agent;
fungal metabolite;
mycotoxin |
| decussatin | [no description available] | low | 0 | 0 | aromatic ether;
phenols;
xanthones | plant metabolite |
| bedaquiline | [no description available] | low | 0 | 0 | aromatic ether;
naphthalenes;
organobromine compound;
quinolines;
tertiary alcohol;
tertiary amino compound | antitubercular agent;
ATP synthase inhibitor |
| dimethomorph | [no description available] | low | 0 | 0 | aromatic ether;
enamide;
monochlorobenzenes;
morpholine fungicide;
tertiary carboxamide | |
| benanomicin b | [no description available] | low | 0 | 0 | aromatic ether;
disaccharide derivative;
L-alanine derivative;
polyketide;
polyphenol;
pradimicin;
secondary alcohol | |
| pradimicin b | [no description available] | low | 0 | 0 | aromatic ether;
L-alanine derivative;
monosaccharide derivative;
polyketide;
polyphenol;
pradimicin;
secondary alcohol | |
| 1,7-dihydroxy-4-methoxyxanthone | [no description available] | low | 0 | 0 | aromatic ether;
phenols;
xanthones | metabolite;
plant metabolite |
| pradimicin a | [no description available] | low | 0 | 0 | aromatic ether;
carboxylic acid;
disaccharide derivative;
L-alanine derivative;
p-quinones;
polyphenol;
pradimicin;
secondary alcohol | |
| clodinafop | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound;
pyridines | EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
phenoxy herbicide |
| ici 118551 | [no description available] | low | 0 | 0 | aromatic ether;
indanes;
secondary alcohol;
secondary amino compound | beta-adrenergic antagonist |
| ochnaflavone | [no description available] | low | 0 | 0 | aromatic ether;
biflavonoid;
hydroxyflavone | anti-inflammatory agent;
antiatherogenic agent;
antibacterial agent;
EC 3.1.1.4 (phospholipase A2) inhibitor;
leukotriene antagonist;
plant metabolite |
| 3-(4-fluorophenoxy)-6-methoxy-2-(4-methoxyphenyl)-1-benzothiophene 1-oxide | [no description available] | low | 0 | 0 | aromatic ether | |
| flavasperone | [no description available] | low | 0 | 0 | aromatic ether;
naphtho-gamma-pyrone;
phenols | acyl-CoA:cholesterol acyltransferase 2 inhibitor;
antiviral agent;
Aspergillus metabolite;
marine metabolite |
| 4-hydroxycordoin | [no description available] | low | 0 | 0 | aromatic ether;
chalcones;
polyphenol | anti-inflammatory agent;
antibacterial agent;
plant metabolite |
| n-feruloylserotonin | [no description available] | low | 0 | 0 | aromatic ether;
cinnamamides;
hydroxyindoles;
phenols;
secondary carboxamide | plant metabolite |
| tyrphostin ag825 | [no description available] | low | 0 | 0 | aromatic ether;
benzothiazoles;
enamide;
nitrile;
organic sulfide;
phenols;
primary carboxamide | epidermal growth factor receptor antagonist |
| kresoxim-methyl | [no description available] | low | 0 | 0 | aromatic ether;
methoxyiminoacetate strobilurin antifungal agent;
methyl ester;
oxime O-ether | antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic |
| 5-methoxy-3,6-diphenyl-1,2,4-triazine | [no description available] | low | 0 | 0 | aromatic ether | |
| pyrachlostrobin | [no description available] | low | 0 | 0 | aromatic ether;
carbamate ester;
carbanilate fungicide;
methoxycarbanilate strobilurin antifungal agent;
monochlorobenzenes;
pyrazoles | antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic |
| piericidin a | [no description available] | low | 0 | 0 | aromatic ether;
methylpyridines;
monohydroxypyridine;
secondary allylic alcohol | antimicrobial agent;
bacterial metabolite;
EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor;
mitochondrial respiratory-chain inhibitor |
| metrafenone | [no description available] | low | 0 | 0 | aromatic ether;
aryl phenyl ketone fungicide;
benzophenones;
organobromine compound | antifungal agrochemical |
| 2-(4-fluoro-3-(trifluoromethyl)phenoxy)-n-(phenylmethyl)butanamide | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
monocarboxylic acid amide;
monofluorobenzenes | |
| b 43 | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
cyclopentanes;
primary amino compound;
pyrrolopyrimidine | EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector |
| 5-(4-phenylbutoxy)psoralen | [no description available] | low | 0 | 0 | aromatic ether;
benzenes;
psoralens | geroprotector;
immunosuppressive agent;
potassium channel blocker |
| 5-ia-85380 | [no description available] | low | 0 | 0 | aromatic ether | |
| yunaconitine | [no description available] | low | 0 | 0 | acetate ester;
aromatic ether;
benzoate ester;
bridged compound;
diterpene alkaloid;
organic heteropolycyclic compound;
polyether;
secondary alcohol;
tertiary alcohol;
tertiary amino compound | antifeedant;
human urinary metabolite;
phytotoxin;
plant metabolite;
xenobiotic |
| ru 58668 | [no description available] | low | 0 | 0 | 17beta-hydroxy steroid;
3-hydroxy steroid;
aromatic ether;
organofluorine compound;
sulfone | anti-estrogen;
antineoplastic agent;
estrogen receptor antagonist |
| altenusin | [no description available] | low | 0 | 0 | aromatic ether;
carboxybiphenyl;
catechols;
hydroxybiphenyls;
polyphenol | antifungal agent;
fungal metabolite |
| gw 501516 | [no description available] | low | 0 | 0 | 1,3-thiazoles;
aromatic ether;
aryl sulfide;
monocarboxylic acid;
organofluorine compound | carcinogenic agent;
PPARbeta/delta agonist |
| bay 58-2667 | [no description available] | low | 0 | 0 | aromatic ether;
benzoic acids;
dicarboxylic acid;
tertiary amino compound | antihypertensive agent;
soluble guanylate cyclase activator;
vasodilator agent |
| camostat | [no description available] | low | 0 | 0 | aromatic ether;
phenols | |
| lenvatinib | [no description available] | low | 0 | 0 | aromatic amide;
aromatic ether;
cyclopropanes;
monocarboxylic acid amide;
monochlorobenzenes;
phenylureas;
quinolines | antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
fibroblast growth factor receptor antagonist;
orphan drug;
vascular endothelial growth factor receptor antagonist |
| nsc 716970 | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
indolecarboxamide;
organochlorine compound | antineoplastic agent |
| lobeglitazone | [no description available] | low | 0 | 0 | aromatic ether | |
| noviflumuron | [no description available] | low | 0 | 0 | aromatic ether;
benzoylurea insecticide;
dichlorobenzene;
organofluorine compound | |
| etomoxir | [no description available] | low | 0 | 0 | aromatic ether | |
| fr 148083 | [no description available] | low | 0 | 0 | aromatic ether;
macrolide;
phenols;
secondary alcohol;
secondary alpha-hydroxy ketone | antibacterial agent;
antineoplastic agent;
metabolite;
NF-kappaB inhibitor |
| 9-methoxycanthin-6-one | [no description available] | low | 0 | 0 | aromatic ether;
indole alkaloid;
organic heterotetracyclic compound | antineoplastic agent;
antiplasmodial drug;
metabolite |
| sb 3ct compound | [no description available] | low | 0 | 0 | aromatic ether | |
| varespladib methyl | [no description available] | low | 0 | 0 | aromatic ether;
benzenes;
indoles;
methyl ester;
primary carboxamide | anti-inflammatory drug;
antidote;
EC 3.1.1.4 (phospholipase A2) inhibitor;
prodrug |
| dapagliflozin | [no description available] | low | 0 | 0 | aromatic ether;
C-glycosyl compound;
monochlorobenzenes | hypoglycemic agent;
sodium-glucose transport protein subtype 2 inhibitor |
| naveglitazar | [no description available] | low | 0 | 0 | aromatic ether | |
| tivozanib | [no description available] | low | 0 | 0 | aromatic ether | |
| zm 447439 | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
morpholines;
polyether;
quinazolines;
secondary amino compound;
tertiary amino compound | antineoplastic agent;
apoptosis inducer;
Aurora kinase inhibitor |
| ustiloxin b | [no description available] | low | 0 | 0 | aromatic ether;
heterodetic cyclic peptide;
macrocycle;
phenols;
secondary alcohol;
secondary carboxamide;
sulfoxide | Aspergillus metabolite;
microtubule-destabilising agent;
mycotoxin |
| hypothemycin | [no description available] | low | 0 | 0 | aromatic ether;
diol;
enone;
epoxide;
macrolide;
phenols;
polyketide;
secondary alpha-hydroxy ketone | antifungal agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
fungal metabolite |
| tryprostatin a | [no description available] | low | 0 | 0 | aromatic ether;
dipeptide;
indole alkaloid;
indoles;
pyrrolopyrazine | breast cancer resistance protein inhibitor |
| cediranib | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-iodothyronamine | [no description available] | low | 0 | 0 | aromatic ether | |
| n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride | [no description available] | low | 0 | 0 | aromatic ether;
hydrochloride;
methoxybenzenes;
tertiary amino compound | antipsychotic agent;
receptor modulator |
| rubraxanthone | [no description available] | low | 0 | 0 | aromatic ether;
polyphenol;
xanthones | antibacterial agent;
antineoplastic agent;
metabolite |
| 7,8-Dihydroyangonin | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| sch 51344 | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
primary alcohol;
pyrazoloquinoline;
secondary amino compound | antineoplastic agent |
| ancistroealaine a | [no description available] | low | 0 | 0 | aromatic ether;
biaryl;
isoquinoline alkaloid;
isoquinolines;
methoxynaphthalene;
methylnaphthalenes | antileishmanial agent;
antiplasmodial drug;
metabolite;
trypanocidal drug |
| pimavanserin | [no description available] | low | 0 | 0 | aromatic ether;
monofluorobenzenes;
piperidines;
tertiary amino compound;
ureas | 5-hydroxytryptamine 2A receptor inverse agonist;
antipsychotic agent;
serotonergic antagonist |
| tolfenpyrad | [no description available] | low | 0 | 0 | aromatic amide;
aromatic ether;
organochlorine compound;
pyrazole insecticide | agrochemical;
antifungal agent;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor;
mitochondrial NADH:ubiquinone reductase inhibitor |
| SIS3 free base | [no description available] | low | 0 | 0 | aromatic ether;
enamide;
isoquinolines;
monocarboxylic acid amide;
pyrrolopyridine;
tertiary carboxamide | Smad3 inhibitor |
| apixaban | [no description available] | low | 0 | 0 | aromatic ether;
lactam;
piperidones;
pyrazolopyridine | anticoagulant;
EC 3.4.21.6 (coagulation factor Xa) inhibitor |
| bibw 2992 | [no description available] | low | 0 | 0 | aromatic ether;
enamide;
furans;
monochlorobenzenes;
organofluorine compound;
quinazolines;
secondary carboxamide;
tertiary amino compound | antineoplastic agent;
tyrosine kinase inhibitor |
| dihydrokavain | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| troglitazone sulfate | [no description available] | low | 0 | 0 | aromatic ether;
thiazolidinone | |
| arisugacin | [no description available] | low | 0 | 0 | aromatic ether;
delta-lactone;
enone;
organic heterotetracyclic compound;
tertiary alcohol | antimicrobial agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite;
Penicillium metabolite |
| saracatinib | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxoles;
diether;
N-methylpiperazine;
organochlorine compound;
oxanes;
quinazolines;
secondary amino compound | anticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
radiosensitizing agent |
| fonsecinone a | [no description available] | low | 0 | 0 | aromatic ether;
aromatic ketone;
biaryl;
cyclic ketone;
naphtho-gamma-pyrone;
polyphenol | antibacterial agent;
Aspergillus metabolite |
| crenolanib | [no description available] | low | 0 | 0 | aminopiperidine;
aromatic ether;
benzimidazoles;
oxetanes;
quinolines;
tertiary amino compound | angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| aiphanol | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxine;
lignan;
stilbenoid | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor |
| nigerloxin | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
benzoic acids;
phenols;
styrenes | antioxidant;
Aspergillus metabolite;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
lipoxygenase inhibitor;
radical scavenger |
| msdc-0160 | [no description available] | low | 0 | 0 | aromatic ether | |
| dihydroxanthohumol | [no description available] | low | 0 | 0 | aromatic ether;
dihydrochalcones;
polyphenol | EC 1.14.13.39 (nitric oxide synthase) inhibitor;
metabolite |
| PB28 | [no description available] | low | 0 | 0 | aromatic ether;
piperazines;
tetralins | anticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
sigma-2 receptor agonist |
| 7-phloroeckol | [no description available] | low | 0 | 0 | aromatic ether;
phlorotannin | antioxidant;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
metabolite |
| 3,5-dimethoxy-4-hydroxybenzyl alcohol-4-O-beta-D-glucopyranoside | [no description available] | low | 0 | 0 | aromatic ether;
benzyl alcohols;
beta-D-glucoside;
monosaccharide derivative;
primary alcohol | antineoplastic agent;
metabolite |
| PDGF receptor tyrosine kinase inhibitor III | [no description available] | low | 0 | 0 | aromatic ether;
N-arylpiperazine;
N-carbamoylpiperazine;
phenylureas;
quinazolines;
tertiary amino compound | EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| fluoxastrobin | [no description available] | low | 0 | 0 | aromatic ether;
dioxazine;
monochlorobenzenes;
organofluorine compound;
oxime O-ether;
pyrimidines;
strobilurin antifungal agent | antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor |
| flumorph | [no description available] | low | 0 | 0 | aromatic ether;
enamide;
morpholines;
organofluorine compound;
tertiary carboxamide | |
| regorafenib | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
phenylureas;
pyridinecarboxamide | antineoplastic agent;
hepatotoxic agent;
tyrosine kinase inhibitor |
| erastin | [no description available] | low | 0 | 0 | aromatic ether;
diether;
monochlorobenzenes;
N-acylpiperazine;
N-alkylpiperazine;
quinazolines;
tertiary carboxamide | antineoplastic agent;
ferroptosis inducer;
voltage-dependent anion channel inhibitor |
| brivanib | [no description available] | low | 0 | 0 | aromatic ether;
diether;
fluoroindole;
pyrrolotriazine;
secondary alcohol | angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
drug metabolite;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
fibroblast growth factor receptor antagonist |
| fg-4592 | [no description available] | low | 0 | 0 | aromatic ether;
isoquinolines;
N-acylglycine | EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor;
EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor |
| picoxystrobin | [no description available] | low | 0 | 0 | aromatic ether;
enoate ester;
enol ether;
methoxyacrylate strobilurin antifungal agent;
organofluorine compound;
pyridines | antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor |
| cenicriviroc | [no description available] | low | 0 | 0 | aromatic ether;
benzazocine;
diether;
imidazoles;
secondary carboxamide;
sulfoxide | anti-HIV agent;
anti-inflammatory agent;
antirheumatic drug;
chemokine receptor 2 antagonist;
chemokine receptor 5 antagonist |
| mandipropamid | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid amide;
monochlorobenzenes;
terminal acetylenic compound | |
| glyceryl ferulate | [no description available] | low | 0 | 0 | 1-monoglyceride;
aromatic ether;
enoate ester;
phenols | antioxidant;
plant metabolite;
ultraviolet filter |
| ki 8751 | [no description available] | low | 0 | 0 | aromatic ether | |
| ceratamine a | [no description available] | low | 0 | 0 | alkaloid;
aromatic ether;
cyclic ketone;
organic heterobicyclic compound;
organobromine compound;
secondary amino compound;
tertiary amine | antimitotic;
metabolite |
| azd 8931 | [no description available] | low | 0 | 0 | aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
piperidines;
quinazolines;
secondary amino compound;
tertiary amino compound | EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
epidermal growth factor receptor antagonist |
| bay94 9172 | [no description available] | low | 0 | 0 | (18)F radiopharmaceutical;
aromatic ether;
polyether;
secondary amino compound;
stilbenoid;
substituted aniline | radioactive imaging agent |
| olodaterol | [no description available] | low | 0 | 0 | aromatic ether;
benzoxazine;
phenols;
secondary alcohol;
secondary amino compound | beta-adrenergic agonist;
bronchodilator agent |
| dorsomorphin | [no description available] | low | 0 | 0 | aromatic ether;
piperidines;
pyrazolopyrimidine;
pyridines | bone morphogenetic protein receptor antagonist;
EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitor |
| cj-042794 | [no description available] | low | 0 | 0 | aromatic ether | |
| hu 308 | [no description available] | low | 0 | 0 | aromatic ether;
bridged compound;
carbobicyclic compound;
primary allylic alcohol;
synthetic cannabinoid | anti-inflammatory agent;
antihypertensive agent;
apoptosis inhibitor;
bone density conservation agent;
CB2 receptor agonist |
| ki11502 | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
quinolines;
thioureas | antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| apremilast | [no description available] | low | 0 | 0 | aromatic ether;
N-acetylarylamine;
phthalimides;
sulfone | non-steroidal anti-inflammatory drug;
phosphodiesterase IV inhibitor |
| PF-00835231 | [no description available] | low | 0 | 0 | aromatic ether;
indolecarboxamide;
L-leucine derivative;
primary alcohol;
pyrrolidin-2-ones;
secondary carboxamide | anticoronaviral agent;
drug metabolite;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor |
| 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine | [no description available] | low | 0 | 0 | aminopyridine;
aromatic ether;
dichlorobenzene;
organofluorine compound;
pyrazolylpiperidine;
racemate | antineoplastic agent;
biomarker;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| chir-265 | [no description available] | low | 0 | 0 | aromatic ether | |
| aminocandin | [no description available] | low | 0 | 0 | aromatic ether;
echinocandin;
homodetic cyclic peptide | antiinfective agent |
| zk 756326 | [no description available] | low | 0 | 0 | aromatic ether | |
| bay 60-6583 | [no description available] | low | 0 | 0 | aminopyridine;
aromatic ether;
aryl sulfide;
cyanopyridine;
cyclopropanes;
monocarboxylic acid amide | adenosine A2B receptor agonist;
anti-inflammatory agent;
cardioprotective agent |
| empagliflozin | [no description available] | low | 0 | 0 | aromatic ether;
C-glycosyl compound;
monochlorobenzenes;
tetrahydrofuryl ether | hypoglycemic agent;
sodium-glucose transport protein subtype 2 inhibitor |
| 4-[5-(4-ethoxyphenyl)-3-isoxazolyl]-N-[(4-methylphenyl)methyl]butanamide | [no description available] | low | 0 | 0 | aromatic ether | |
| bgt226 | [no description available] | low | 0 | 0 | aromatic ether;
imidazoquinoline;
N-arylpiperazine;
organofluorine compound;
pyridines | antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor |
| n-desmethylrosiglitazone | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(5-methyl-3-nitro-1-pyrazolyl)-N-[3-(4-methylphenoxy)-5-nitrophenyl]butanamide | [no description available] | low | 0 | 0 | aromatic ether | |
| verruculogen | [no description available] | low | 0 | 0 | aromatic ether;
diol;
indole alkaloid;
organic heterohexacyclic compound;
organic peroxide | Aspergillus metabolite;
GABA modulator;
mycotoxin;
Penicillium metabolite;
potassium channel blocker |
| 1-O-feruloyl-beta-D-glucose | [no description available] | low | 0 | 0 | aromatic ether;
beta-D-glucoside;
cinnamate ester;
phenols | antioxidant;
plant metabolite |
| 2,2',4,5'-tetrabromodiphenyl ether | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound | |
| hexabromodiphenyl ether 154 | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound | |
| bde 183 | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound | |
| l-798106 | [no description available] | low | 0 | 0 | aromatic ether;
bromobenzenes;
N-sulfonylcarboxamide | prostaglandin receptor antagonist |
| aflatoxin m1 | [no description available] | low | 0 | 0 | aflatoxin;
aromatic ether;
aromatic ketone;
tertiary alcohol | Aspergillus metabolite;
human xenobiotic metabolite;
mammalian metabolite |
| macitentan | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound;
pyrimidines;
ring assembly;
sulfamides | antihypertensive agent;
endothelin receptor antagonist;
orphan drug |
| CDN1163 | [no description available] | low | 0 | 0 | aromatic ether;
quinolines;
secondary carboxamide | SERCA activator |
| e 7050 | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[(5-chloro-2-thiophenyl)methyl]-5-[(2,6-difluorophenoxy)methyl]-3-isoxazolecarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| dafadine C | [no description available] | low | 0 | 0 | aromatic amide;
aromatic ether;
difluorobenzene;
isoxazoles;
N-acylpiperidine;
pyridines | P450 inhibitor |
| dafadine B | [no description available] | low | 0 | 0 | aromatic amide;
aromatic ether;
isoxazoles;
monochlorobenzenes;
monofluorobenzenes;
N-acylpiperidine;
pyridines | P450 inhibitor |
| 3-[5-(5-methyl-2-thiophenyl)-1,3,4-oxadiazol-2-yl]-N-[2-(3-pyridinyloxy)propyl]propanamide | [no description available] | low | 0 | 0 | aromatic ether | |
| violaceol II | [no description available] | low | 0 | 0 | aromatic ether;
catechols;
resorcinols | mycotoxin |
| pamapimod | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
difluorobenzene;
diol;
primary alcohol;
pyridopyrimidine;
secondary amino compound | antirheumatic drug;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| gsk690693 | [no description available] | low | 0 | 0 | 1,2,5-oxadiazole;
acetylenic compound;
aromatic amine;
aromatic ether;
imidazopyridine;
piperidines;
primary amino compound;
tertiary alcohol | antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| cnf 2024 | [no description available] | low | 0 | 0 | 2-aminopurines;
aromatic ether;
organochlorine compound;
pyridines | antineoplastic agent;
Hsp90 inhibitor |
| uk 453,061 | [no description available] | low | 0 | 0 | aromatic ether | |
| 8-{1-[4-(dimethylamino)phenyl]-3-(pyrrolidin-1-yl)propyl}-5,7-dimethoxy-4-pentyl-2H-chromen-2-one | [no description available] | low | 0 | 0 | aromatic ether;
coumarins;
pyrrolidines;
tertiary amino compound | |
| zm323881 | [no description available] | low | 0 | 0 | aromatic ether;
benzyl ether;
fluorophenol;
halophenol;
monofluorobenzenes;
organic cation;
quinazolines;
secondary amino compound;
substituted aniline | vascular endothelial growth factor receptor antagonist |
| compound w | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[[4-[2-[(2-methylpropan-2-yl)oxy]anilino]-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanol | [no description available] | low | 0 | 0 | aromatic ether | |
| interiotherin b | [no description available] | low | 0 | 0 | aromatic ether;
fatty acid ester;
lignan;
organic heteropentacyclic compound;
oxacycle | anti-HIV agent;
metabolite |
| 5,7-dihydroxy-3-(3-hydroxy-4-methoxybenzyl)-6-methoxychroman-4-one | [no description available] | low | 0 | 0 | aromatic ether;
homoisoflavonoid;
polyphenol | angiogenesis modulating agent;
plant metabolite |
| ph 797804 | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
organobromine compound;
organofluorine compound;
pyridone | anti-inflammatory agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| diorcinol | [no description available] | low | 0 | 0 | aromatic ether;
phenols | fungal metabolite;
marine metabolite;
metabolite |
| 2-[[4-(2-phenoxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanol | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[[4-(1-pyrrolidinyl)-6-[2-(trifluoromethoxy)anilino]-1,3,5-triazin-2-yl]amino]ethanol | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[[4-(5-chloro-2-ethoxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanol | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[[4-(5-chloro-2-propan-2-yloxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanol | [no description available] | low | 0 | 0 | aromatic ether | |
| mk 5108 | [no description available] | low | 0 | 0 | aromatic ether | |
| lde225 | [no description available] | low | 0 | 0 | aminopyridine;
aromatic ether;
benzamides;
biphenyls;
morpholines;
organofluorine compound;
tertiary amino compound | antineoplastic agent;
Hedgehog signaling pathway inhibitor;
SMO receptor antagonist |
| 1-azepanyl-[5-[(4-chloro-3,5-dimethylphenoxy)methyl]-3-isoxazolyl]methanone | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(1-((5-((2,6-dimethylphenoxy)methyl)-3-isoxazolyl)carbonyl)-4-piperidinyl)pyridine | [no description available] | low | 0 | 0 | aromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
pyridines | geroprotector;
P450 inhibitor |
| dafadine D | [no description available] | low | 0 | 0 | aromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
organofluorine compound;
pyridines | P450 inhibitor |
| 1-[(1-ethyl-3-methyl-4-pyrazolyl)methyl]-N-[4-(2-fluorophenoxy)phenyl]-4-piperidinecarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| dafadine O | [no description available] | low | 0 | 0 | aromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
pyridines;
ring assembly | P450 inhibitor |
| 5-[(3,4-dimethylphenoxy)methyl]-N-methyl-N-(4-oxanylmethyl)-3-isoxazolecarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| pci 32765 | [no description available] | low | 0 | 0 | acrylamides;
aromatic amine;
aromatic ether;
N-acylpiperidine;
pyrazolopyrimidine;
tertiary carboxamide | antineoplastic agent;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor |
| florbetapir f 18 | [no description available] | low | 0 | 0 | (18)F radiopharmaceutical;
aromatic ether;
organofluorine compound;
pyridines;
substituted aniline | radioactive imaging agent |
| AMG-208 | [no description available] | low | 0 | 0 | aromatic ether;
quinolines;
triazolopyridazine | antineoplastic agent;
c-Met tyrosine kinase inhibitor |
| 6-methoxyspirotryprostatin b | [no description available] | low | 0 | 0 | aromatic ether;
azaspiro compound;
indole alkaloid;
indolones | antineoplastic agent;
Aspergillus metabolite |
| lucitanib | [no description available] | low | 0 | 0 | aromatic ether;
cyclopropanes;
naphthalenecarboxamide;
primary amino compound;
quinolines | antineoplastic agent;
fibroblast growth factor receptor antagonist;
vascular endothelial growth factor receptor antagonist |
| act-132577 | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound;
pyrimidines;
sulfamides | antihypertensive agent;
drug metabolite;
endothelin receptor antagonist;
xenobiotic metabolite |
| cabozantinib | [no description available] | low | 0 | 0 | aromatic ether;
dicarboxylic acid diamide;
organofluorine compound;
quinolines | antineoplastic agent;
tyrosine kinase inhibitor |
| poziotinib | [no description available] | low | 0 | 0 | acrylamides;
aromatic ether;
dichlorobenzene;
diether;
monofluorobenzenes;
N-acylpiperidine;
quinazolines;
secondary amino compound;
substituted aniline | antineoplastic agent;
apoptosis inducer;
epidermal growth factor receptor antagonist |
| gsk 2126458 | [no description available] | low | 0 | 0 | aromatic ether;
difluorobenzene;
pyridazines;
pyridines;
quinolines;
sulfonamide | anticoronaviral agent;
antineoplastic agent;
autophagy inducer;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor;
radiosensitizing agent |
| gsk 1363089 | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(methylsulfonyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-propan-2-ylurea | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(methylsulfonyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-3-propan-2-ylurea | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-cyclohexyl-1-[[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-8-[[oxo-(propan-2-ylamino)methyl]amino]-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-1-methylurea | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-cyclohexyl-1-[[(2S,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-10-[[oxo-(propan-2-ylamino)methyl]amino]-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-1-methylurea | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[(4-phenoxyphenyl)methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-4-pyridinecarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(3,5-dimethyl-4-isoxazolyl)-3-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]urea | [no description available] | low | 0 | 0 | aromatic ether | |
| monepantel | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
aryl sulfide;
nitrile;
secondary carboxamide | anthelminthic drug;
nematicide |
| an2728 | [no description available] | low | 0 | 0 | aromatic ether;
benzoxaborole;
nitrile | antipsoriatic;
non-steroidal anti-inflammatory drug;
phosphodiesterase IV inhibitor |
| grazoprevir | [no description available] | low | 0 | 0 | aromatic ether;
azamacrocycle;
carbamate ester;
cyclopropanes;
lactam;
N-sulfonylcarboxamide;
quinoxaline derivative | antiviral drug;
hepatitis C protease inhibitor;
hepatoprotective agent |
| hordatine a | [no description available] | low | 0 | 0 | aromatic ether;
benzofurans;
dicarboxylic acid diamide;
guanidines;
phenols | adrenergic antagonist;
metabolite |
| 5-chloro-2-(3,5-dimethylphenyl)-4-(4-methoxyphenoxy)-3-pyridazinone | [no description available] | low | 0 | 0 | aromatic ether | |
| tak-632 | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
benzothiazoles;
cyclopropylcarboxamide;
monofluorobenzenes;
nitrile;
secondary carboxamide | antineoplastic agent;
apoptosis inducer;
B-Raf inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
necroptosis inhibitor |
| lrrk2-in1 | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
N-acylpiperidine;
N-alkylpiperazine;
pyrimidobenzodiazepine;
secondary amino compound;
tertiary amino compound | antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| quinolobactin | [no description available] | low | 0 | 0 | aromatic ether;
monohydroxyquinoline;
phenols;
quinolinemonocarboxylic acid | bacterial metabolite;
siderophore |
| AZD1979 | [no description available] | low | 0 | 0 | aromatic ether;
azaspiro compound;
carboxamide;
N-acylazetidine;
oxadiazole;
oxaspiro compound;
oxetanes | melanin-concentrating hormone receptor antagonist |
| ML240 | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
benzimidazoles;
primary amino compound;
quinazolines;
secondary amino compound | antineoplastic agent |
| aripiprazole lauroxil | [no description available] | low | 0 | 0 | aromatic ether;
delta-lactam;
dichlorobenzene;
dodecanoate ester;
N-alkylpiperazine;
N-arylpiperazine;
quinolone | H1-receptor antagonist;
prodrug;
second generation antipsychotic;
serotonergic agonist |
| abt-199 | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
N-sulfonylcarboxamide;
oxanes;
pyrrolopyridine | antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor |
| xl765 | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
benzamides;
quinoxaline derivative;
sulfonamide | antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor |
| DMH1 | [no description available] | low | 0 | 0 | aromatic ether;
pyrazolopyrimidine;
quinolines | antineoplastic agent;
bone morphogenetic protein receptor antagonist;
protein kinase inhibitor |
| 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide | [no description available] | low | 0 | 0 | aromatic ether;
methylpyridines;
olefinic compound;
quinazolines;
secondary amino compound;
secondary carboxamide;
toluenes | |
| pf 4800567 | [no description available] | low | 0 | 0 | aromatic ether;
monochlorobenzenes;
oxanes;
pyrazolopyrimidine | EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| propenylphosphonic acid | [no description available] | low | 0 | 0 | aromatic ether | |
| abt-333 | [no description available] | low | 0 | 0 | aromatic ether;
naphthalenes;
pyrimidone;
sulfonamide | antiviral drug;
nonnucleoside hepatitis C virus polymerase inhibitor |
| naloxegol | [no description available] | low | 0 | 0 | aromatic ether;
organic heteropentacyclic compound;
phenols;
polyether;
tertiary alcohol | cathartic;
mu-opioid receptor antagonist |
| ceritinib | [no description available] | low | 0 | 0 | aminopyrimidine;
aromatic ether;
organochlorine compound;
piperidines;
secondary amino compound;
sulfone | antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| MK-8353 | [no description available] | low | 0 | 0 | aromatic ether;
dihydropyridine;
indazoles;
methyl sulfide;
N-alkylpyrrolidine;
pyridines;
pyrrolidinecarboxamide;
secondary carboxamide;
tertiary carboxamide;
triazoles | antineoplastic agent;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| HG-10-102-01 | [no description available] | low | 0 | 0 | aminopyrimidine;
aromatic ether;
monocarboxylic acid amide;
morpholines;
organochlorine compound;
secondary amino compound | EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| N-[(5-methyl-2-furanyl)methylideneamino]-2-phenoxybenzamide | [no description available] | low | 0 | 0 | aromatic ether | |
| saroglitazar | [no description available] | low | 0 | 0 | aromatic ether;
methyl sulfide;
monocarboxylic acid;
pyrroles | hypoglycemic agent;
PPARalpha agonist;
PPARgamma agonist |
| fertaric acid | [no description available] | low | 0 | 0 | aromatic ether;
cinnamate ester;
dicarboxylic acid;
phenols;
tetraric acid derivative | |
| 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
tertiary alcohol;
triazoles | |
| pf-06463922 | [no description available] | low | 0 | 0 | aminopyridine;
aromatic ether;
azamacrocycle;
benzamides;
cyclic ether;
monofluorobenzenes;
nitrile;
organic heterotetracyclic compound;
pyrazoles | antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| DDR1-IN-1 | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
benzamides;
N-alkylpiperazine;
oxindoles;
secondary carboxamide | EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| ldc4297 | [no description available] | low | 0 | 0 | aromatic ether;
piperidines;
pyrazoles;
pyrazolotriazine;
secondary amino compound | antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor |
| MLI-2 | [no description available] | low | 0 | 0 | aromatic ether;
cyclopropanes;
indazoles;
morpholines;
pyrimidines;
tertiary amino compound | EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| ap20187 | [no description available] | low | 0 | 0 | aromatic ether;
carboxylic ester;
N-acylpiperidine;
tertiary amino compound | ligand |
| biliatresone | [no description available] | low | 0 | 0 | aromatic ether;
aromatic ketone;
benzodioxoles;
enone;
phenols | plant metabolite;
toxin |
| tak 491 | [no description available] | low | 0 | 0 | 1,2,4-oxadiazole;
aromatic ether;
benzimidazoles;
carboxylic ester;
cyclic carbonate ester;
dioxolane | angiotensin receptor antagonist;
antihypertensive agent;
prodrug |
| azilsartan | [no description available] | low | 0 | 0 | 1,2,4-oxadiazole;
aromatic ether;
benzimidazolecarboxylic acid | angiotensin receptor antagonist;
antihypertensive agent |
| hydrazinocurcumin | [no description available] | low | 0 | 0 | aromatic ether;
olefinic compound;
polyphenol;
pyrazoles | angiogenesis modulating agent;
antineoplastic agent;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| mirodenafil | [no description available] | low | 0 | 0 | aromatic ether;
N-alkylpiperazine;
primary alcohol;
pyrrolopyrimidine;
sulfonamide | EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor;
vasodilator agent |
| cerulomycin | [no description available] | low | 0 | 0 | aldoxime;
aromatic ether;
bipyridines;
pyridine alkaloid | antineoplastic agent;
bacterial metabolite;
marine metabolite |
| undecylprodigiosin | [no description available] | low | 0 | 0 | alkaloid;
aromatic ether;
tripyrrole | antibacterial agent;
antineoplastic agent;
apoptosis inducer;
bacterial metabolite;
biological pigment;
immunosuppressive agent;
radiosensitizing agent |
| sb-590885 | [no description available] | low | 0 | 0 | aromatic ether;
imidazoles;
ketoxime;
pyridines;
tertiary amino compound | |
| 2-[[4-(trifluoromethoxy)phenyl]methylthio]-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-one | [no description available] | low | 0 | 0 | aromatic ether | |
| PF-07304814 | [no description available] | low | 0 | 0 | aromatic ether;
indolecarboxamide;
L-leucine derivative;
phosphate monoester;
pyrrolidin-2-ones;
secondary carboxamide | anticoronaviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
prodrug |