Page last updated: 2024-12-10

2-(4-(1-(4-hydroxyphenyl)-2-(4-isopropylphenyl)-1-butenyl)phenoxy)-n,n-dimethylethylamine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

The chemical you've described, **2-(4-(1-(4-hydroxyphenyl)-2-(4-isopropylphenyl)-1-butenyl)phenoxy)-N,N-dimethylethylamine**, is a complex organic molecule with a long and descriptive name. To break it down and understand its potential importance in research:

**Structure and Components:**

* **Basic Structure:** It's likely a substituted amine with a long, branched alkyl chain connected to the amine nitrogen. This chain contains multiple aromatic rings and functional groups.
* **Aromatic Rings:** The presence of phenyl groups (C6H5) indicates benzene rings. 4-hydroxyphenyl suggests a benzene ring with an OH (hydroxyl) group at the 4th position. 4-isopropylphenyl indicates a benzene ring with an isopropyl group (CH(CH3)2) at the 4th position.
* **Alkyl Chain:** The butenyl suggests a four-carbon chain containing a double bond.
* **Functional Groups:** N,N-dimethylethylamine tells us the molecule is an amine with two methyl groups (CH3) attached to the nitrogen atom. The phenoxy portion indicates an ether linkage (R-O-R') between an aromatic ring and the alkyl chain.

**Potential Research Significance:**

Given the complexity of this molecule and its various functional groups, it's likely to have potential applications in several research areas:

1. **Pharmaceuticals:**
* **Drug Development:** The presence of aromatic rings, a hydroxyl group, and an amine suggests this molecule could potentially interact with biological systems. It could have activity as a drug candidate for conditions like:
* **Central Nervous System (CNS) Disorders:** The amine group is common in neurotransmitters and drugs acting on the CNS.
* **Inflammation:** The hydroxyl group can contribute to anti-inflammatory properties.
* **Targeting Specific Receptors:** The structure might be designed to bind to specific receptors or enzymes.
2. **Materials Science:**
* **Polymers:** This molecule might serve as a building block in the synthesis of new polymers with desirable properties, such as conductivity, strength, or biocompatibility.
3. **Analytical Chemistry:**
* **Chromatography:** Its unique structure could make it a useful standard for developing new analytical methods.

**Important Considerations:**

* **Specificity:** Without further information, it's impossible to definitively say what the molecule's exact function or purpose is.
* **Research Context:** The significance of the molecule will depend heavily on the specific research project or context in which it's being investigated.

**To learn more, you would need additional information:**

* **What is the molecule's purpose in the research?**
* **What are the specific biological or chemical properties of the molecule?**
* **What are the results of the research involving this molecule?**

By researching the specific context of its use, you can gain a better understanding of the importance of this chemical in research.

2-(4-(1-(4-hydroxyphenyl)-2-(4-isopropylphenyl)-1-butenyl)phenoxy)-N,N-dimethylethylamine: structure given in first source; DP-TAT-59 is the Z isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID3037015
CHEMBL ID2074961
SCHEMBL ID34173
MeSH IDM0177898

Synonyms (19)

Synonym
miproxifene
dp-tat-59
(z)-alpha-(p-(2-(dimethylamino)ethoxy)phenyl)-alpha'-ethyl-4'-isopropyl-4-stilbenol
miproxifene [inn]
129612-87-9
phenol, 4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-(4-(1-methyletthyl)phenyl)-1-butenyl)-, (z)-
bgj4z7930w ,
unii-bgj4z7930w
2-oh-dm-dp
2-(4-(1-(4-hydroxyphenyl)-2-(4-isopropylphenyl)-1-butenyl)phenoxy)-n,n-dimethylethylamine
CHEMBL2074961
miproxifene [who-dd]
(z)-.alpha.-(p-(2-(dimethylamino)ethoxy)phenyl)-.alpha.'-ethyl-4'-isopropyl-4-stilbenol
SCHEMBL34173
C21549
(z)-2-(4-(1-(4-hydroxyphenyl)-2-(4-isopropyl-phenyl)-1-butenyl)phenoxy)-n,n-dimethyl-ethylamine
4-[(z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-(4-propan-2-ylphenyl)but-1-enyl]phenol
Q27274659
DTXSID301318241
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID681343TP_TRANSPORTER: inhibition of topotecan uptake in BCRP-expressing K562 cells2003Molecular cancer therapeutics, Jan, Volume: 2, Issue:1
Reversal of breast cancer resistance protein-mediated drug resistance by estrogen antagonists and agonists.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's6 (75.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.82

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.82 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.21 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.82)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (11.11%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (88.89%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]