2-(3-ethylureido)-6-methylpyridine profile

The chemical name 2-(3-ethylureido)-6-methylpyridine refers to a specific organic compound.

**Structure:**

* **Pyridine:** The core structure is a pyridine ring, which is a six-membered aromatic ring containing one nitrogen atom.
* **Substitutions:**
* **Methyl group:** A methyl group (CH3) is attached at the 6-position of the pyridine ring.
* **Ethylureido group:** An ethylureido group (-NHCONHCH2CH3) is attached at the 2-position of the pyridine ring.

**Potential Importance for Research:**

While I don't have access to specific research papers, it's possible that this compound could be important for research in the following areas:

* **Pharmacology/Medicinal Chemistry:**
* **Drug Discovery:** The molecule could be a lead compound for developing new drugs. Its specific structure might interact with biological targets, like enzymes or receptors, leading to therapeutic effects.
* **Structure-Activity Relationship (SAR):** Studying modifications to this molecule could help scientists understand how changes in structure affect its biological activity.

* **Materials Science:**
* **Polymers/Organic Electronics:** This compound could potentially be used as a monomer to synthesize novel polymers with unique properties, such as conductivity or light-emitting capabilities.

* **Chemical Synthesis:**
* **Building Blocks:** This compound could serve as a starting material or intermediate for synthesizing other complex molecules.

**How to Find More Information:**

To learn more about the specific research significance of this compound, you would need to:

1. **Consult scientific databases:** Databases like PubMed (for biomedical research), SciFinder (for chemical information), or Google Scholar can help you find relevant research papers.
2. **Search for patents:** If this compound has potential applications, it might be mentioned in patent databases.
3. **Contact experts:** Reach out to researchers in related fields (e.g., medicinal chemistry, organic synthesis) who might have knowledge of this molecule.

**Note:** Without a clear context or specific research goal, it's impossible to definitively say why this compound is important. The importance depends on the specific research being conducted.

2-(3-ethylureido)-6-methylpyridine: a potent inducer of cell differentiation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	126618
CHEMBL ID	1977341
MeSH ID	M0269172

Synonym
NCI60_019706
nsc-656958
nsc656958
udp 4
1-ethyl-3-(6-methylpyridin-2-yl)urea
2-(3-ethylureido)-6-methylpyridine
urea, n-ethyl-n'-(6-methyl-2-pyridinyl)-
udp-4
n-ethyl-n'-(6-methyl-2-pyridinyl)urea
141766-10-1
CHEMBL1977341
DTXSID70161819

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	1 (20.00)	18.7374
1990's	1 (20.00)	18.2507
2000's	2 (40.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (20.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
dimethyl sulfoxide Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.. dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.	2.41	2	sulfoxide; volatile organic compound	alkylating agent; antidote; Escherichia coli metabolite; geroprotector; MRI contrast agent; non-narcotic analgesic; polar aprotic solvent; radical scavenger
uracil 2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder	1.93	1	pyrimidine nucleobase; pyrimidone	allergen; Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; prodrug; Saccharomyces cerevisiae metabolite
urea pseudourea: clinical use; structure. isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.	3.09	5	isourea; monocarboxylic acid amide; one-carbon compound	Daphnia magna metabolite; Escherichia coli metabolite; fertilizer; flour treatment agent; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
tetradecanoylphorbol acetate Tetradecanoylphorbol Acetate: A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA.. phorbol ester : Esters of phorbol, originally found in croton oil (from Croton tiglium, of the family Euphorbiaceae). A number of phorbol esters possess activity as tumour promoters and activate the mechanisms associated with cell growth. Some of these are used in experiments as activators of protein kinase C.. phorbol 13-acetate 12-myristate : A phorbol ester that is phorbol in which the hydroxy groups at the cyclopropane ring juction (position 13) and the adjacent carbon (position 12) have been converted into the corresponding acetate and myristate esters. It is a major active constituent of the seed oil of Croton tiglium. It has been used as a tumour promoting agent for skin carcinogenesis in rodents and is associated with increased cell proliferation of malignant cells. However its function is controversial since a decrease in cell proliferation has also been observed in several cancer cell types.	1.99	1	acetate ester; diester; phorbol ester; tertiary alpha-hydroxy ketone; tetradecanoate ester	antineoplastic agent; apoptosis inducer; carcinogenic agent; mitogen; plant metabolite; protein kinase C agonist; reactive oxygen species generator
adenosine quinquefolan B: isolated from roots of Panax quinquefolium L.; RN not in Chemline 10/87; RN from Toxlit	2.41	2	adenosines; purines D-ribonucleoside	analgesic; anti-arrhythmia drug; fundamental metabolite; human metabolite; vasodilator agent
n-methyladenosine N-methyladenosine: is a inhibitor of cell differentiation. N(6)-methyladenosine : A methyladenosine compound with one methyl group attached to N(6) of the adenine nucleobase.	2.41	2	methyladenosine
tretinoin Tretinoin: An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).. retinoic acid : A retinoid consisting of 3,7-dimethylnona-2,4,6,8-tetraenoic acid substituted at position 9 by a 2,6,6-trimethylcyclohex-1-en-1-yl group (geometry of the four exocyclic double bonds is not specified).. all-trans-retinoic acid : A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.	2.41	1	retinoic acid; vitamin A	anti-inflammatory agent; antineoplastic agent; antioxidant; AP-1 antagonist; human metabolite; keratolytic drug; retinoic acid receptor agonist; retinoid X receptor agonist; signalling molecule
epidermal growth factor Epidermal Growth Factor: A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form.	1.99	1

Condition	Relationship Strength	Studies
(pPNET) Peripheral Primitive Neuroectodermal Tumors [description not available]	1.99	1
Rhabdomyosarcoma A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9)	1.99	1
Neuroectodermal Tumors, Primitive, Peripheral A group of highly cellular primitive round cell neoplasms which occur extracranially in soft tissue and bone and are derived from embryonal neural crest cells. These tumors occur primarily in children and adolescents and share a number of characteristics with EWING SARCOMA.	1.99	1
Di Guglielmo Disease [description not available]	2.41	2
Leukemia, Erythroblastic, Acute A myeloproliferative disorder characterized by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood.	2.41	2

2-(3-ethylureido)-6-methylpyridine

Description

Cross-References

Synonyms (12)

Research

Studies (5)

Market Indicators

Research Demand Index: 12.74

Study Types