2-(3-chlorophenyl)-5-(prop-2-enylamino)-4-oxazolecarbonitrile

2-(3-chlorophenyl)-5-(prop-2-enylamino)-4-oxazolecarbonitrile, also known as **GW842507X**, is a **potent and selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4)**.

Here's why it's important for research:

* **Diabetes Treatment:** DPP-4 is a key enzyme involved in the degradation of incretin hormones, like GLP-1 and GIP, which play a crucial role in regulating blood glucose levels. Inhibiting DPP-4 allows these incretins to persist in the bloodstream for longer, leading to increased insulin secretion and improved glucose control. This makes GW842507X a promising candidate for the treatment of type 2 diabetes.
* **Metabolic Disorders:** DPP-4 inhibition has also been linked to benefits in other metabolic disorders, such as obesity and cardiovascular disease.
* **Drug Development:** GW842507X has served as a valuable tool in understanding the role of DPP-4 in various physiological processes. Its high selectivity and potency have made it a useful model compound for the development of novel DPP-4 inhibitors with improved therapeutic properties.
* **Research into DPP-4:** GW842507X's ability to inhibit DPP-4 has allowed researchers to study the enzyme's function in more detail and explore its potential involvement in other biological processes.

**It's important to note that:**

* While GW842507X holds promise as a potential drug, it is not currently commercially available.
* Further research is ongoing to evaluate its safety and efficacy in humans.

Overall, 2-(3-chlorophenyl)-5-(prop-2-enylamino)-4-oxazolecarbonitrile (GW842507X) is a significant research tool that has contributed to our understanding of DPP-4 and its potential as a target for drug development. It is a potent and selective inhibitor of DPP-4, which makes it valuable for studying the role of this enzyme in various metabolic disorders and for developing new treatments for diabetes and other related conditions.