2-(2-thenyl)sulfonyl-5-bromopyrimidine

Description

2-(2-Thenyl)sulfonyl-5-bromopyrimidine is a chemical compound with the molecular formula C₉H₇BrN₂O₂S. It is a derivative of pyrimidine, a heterocyclic aromatic compound found in many biological systems, including DNA and RNA.

Here's a breakdown of its structure and why it is important for research:

**Structure:**

* **Pyrimidine core:** The molecule is based on a pyrimidine ring, a six-membered ring containing two nitrogen atoms.
* **Thiophene ring:** It has a thiophene ring (C₄H₄S) attached to the pyrimidine ring via a methylene bridge (-CH₂-).
* **Sulfonyl group:** A sulfonyl group (-SO₂-) is attached to the thiophene ring.
* **Bromine substituent:** A bromine atom is attached to the pyrimidine ring at the 5-position.

**Importance for Research:**

This specific compound is of interest to researchers for several potential applications:

* **Pharmaceutical Research:**
* **Anti-cancer activity:** Some pyrimidine derivatives, including those with sulfonyl groups, have shown potential as anticancer agents. The bromine substitution might influence its activity.
* **Anti-inflammatory activity:** Some thiophene derivatives have shown anti-inflammatory properties. This compound might exhibit similar activity.
* **Organic Chemistry:**
* **New synthetic methods:** The compound could serve as a starting material for the synthesis of other complex organic molecules.
* **Mechanistic studies:** Its reactivity and properties can be studied to gain a better understanding of chemical transformations.
* **Materials Science:**
* **Photoluminescence:** Some thiophene-containing molecules exhibit interesting photoluminescent properties, potentially useful in organic light-emitting diodes (OLEDs).
* **Conductivity:** The sulfonyl group and the aromatic rings could influence the conductivity of the compound, making it potentially relevant for electronic applications.

**Overall:** 2-(2-Thenyl)sulfonyl-5-bromopyrimidine is a relatively new molecule with a unique combination of structural features. Its potential as a lead compound in drug discovery, a synthetic reagent, or a functional material is currently under investigation.

**Important Note:** Research on this specific compound is likely in its early stages. It's essential to consult peer-reviewed scientific publications or specialist databases for the latest findings and to avoid making assumptions about its exact biological or chemical properties without solid research evidence.

2-(2-thenyl)sulfonyl-5-bromopyrimidine: induces cell cycle specific inhibition in metaphase; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]