2-(2-chlorophenyl)-5-(2-methylpropylamino)-4-oxazolecarbonitrile

2-(2-chlorophenyl)-5-(2-methylpropylamino)-4-oxazolecarbonitrile is a chemical compound with the molecular formula C14H14ClN3O. It is a **selective inhibitor of the enzyme carbonic anhydrase IX (CAIX)**.

Here's why this compound is important for research:

**Carbonic Anhydrase IX (CAIX)**

* **Role in cancer:** CAIX is an enzyme that plays a crucial role in tumor growth and metastasis. It helps regulate the pH of the tumor microenvironment, making it more acidic and promoting cancer cell survival.
* **Potential therapeutic target:** Inhibiting CAIX has emerged as a promising therapeutic strategy for cancer treatment.

**2-(2-chlorophenyl)-5-(2-methylpropylamino)-4-oxazolecarbonitrile as a CAIX inhibitor:**

* **High selectivity:** This compound exhibits strong inhibitory activity against CAIX while having minimal effects on other isoforms of carbonic anhydrase, making it a promising lead compound for drug development.
* **Potential applications:** This compound and its analogues are being investigated for their potential in:
* **Cancer therapy:** Preventing tumor growth and metastasis.
* **Diagnostic imaging:** Developing imaging agents for detecting tumors.

**Research significance:**

* **Understanding CAIX biology:** This compound serves as a valuable tool to further investigate the role of CAIX in cancer development and the mechanisms of its inhibition.
* **Drug discovery:** The development of selective CAIX inhibitors like this compound represents a significant advancement in the fight against cancer.

**Note:** This compound is still under investigation and is not currently approved for clinical use. However, its promising properties make it a valuable target for further research and development.