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2-(2,5-dimethoxy-4-methylphenyl)cyclopropylamine

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Description

2-(2,5-dimethoxy-4-methylphenyl)cyclopropylamine: RN given refers to parent cpd without isomeric designation; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID3017965
CHEMBL ID13530
SCHEMBL ID20970871
MeSH IDM0071739

Synonyms (6)

Synonym
CHEMBL13530
2-(2,5-dimethoxy-4-methylphenyl)cyclopropylamine
4-methyl-2,5-methoxyphenylcyclopropylamine
Q4637171
SCHEMBL20970871
DTXSID10990120
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (7)

Assay IDTitleYearJournalArticle
AID178581Effective dose to cause hallucinogenic activity in rats using drug discrimination assay by intraperitoneal administration1984Journal of medicinal chemistry, Sep, Volume: 27, Issue:9
Synthesis and evaluation of substituted 2-phenylcyclobutylamines as analogues of hallucinogenic phenethylamines: lack of LSD-like biological activity.
AID29136Acid dissociation constant was determined1981Journal of medicinal chemistry, Jul, Volume: 24, Issue:7
Synthesis and serotonin-like activity of 2-amino-5,8-dimethoxy-6-methyl-1,2-dihydronaphthalene.
AID123358Evaluated for ear-scratch response (hallucinogen like activity) in mice at a dose of 5.00 mg/Kg1982Journal of medicinal chemistry, May, Volume: 25, Issue:5
Isomeric cyclopropyl ring-methylated homologues of trans-2-(2,5-dimethoxy-4-methylphenyl)cyclopropylamine, an hallucinogen analogue.
AID123227Evaluated for ear-scratch response (hallucinogen like activity) in mice at a dose of 10.00 mg/Kg1982Journal of medicinal chemistry, May, Volume: 25, Issue:5
Isomeric cyclopropyl ring-methylated homologues of trans-2-(2,5-dimethoxy-4-methylphenyl)cyclopropylamine, an hallucinogen analogue.
AID123356Evaluated for ear-scratch response (hallucinogen like activity) in mice at a dose of 20.00 mg/Kg1982Journal of medicinal chemistry, May, Volume: 25, Issue:5
Isomeric cyclopropyl ring-methylated homologues of trans-2-(2,5-dimethoxy-4-methylphenyl)cyclopropylamine, an hallucinogen analogue.
AID185012Compound was evaluated for mean % LSD correct responses at a dos e of 0.75 mg/kg in rats using drug discrimination assay1984Journal of medicinal chemistry, Sep, Volume: 27, Issue:9
Synthesis and evaluation of substituted 2-phenylcyclobutylamines as analogues of hallucinogenic phenethylamines: lack of LSD-like biological activity.
AID91217Compound tested for hallucinogenic activity in humans was reported; Value reported in (A)= Mescaline units1998Journal of medicinal chemistry, Sep-24, Volume: 41, Issue:20
The frontier orbital phase angles: novel QSAR descriptors for benzene derivatives, applied to phenylalkylamine hallucinogens.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]