2-(2',3',5'-triiodobenzoyl)ethyl methacrylate

Description

## 2-(2',3',5'-Triiodobenzoyl)ethyl methacrylate: A Key Player in Bio-Imaging

**2-(2',3',5'-Triiodobenzoyl)ethyl methacrylate (TIBEM)** is a specialized monomer used in the synthesis of **polymers with high X-ray opacity**. This unique property makes TIBEM crucial for a range of research applications, particularly in the fields of:

**1. Bio-Imaging:**

* **Contrast enhancement in X-ray imaging:** Due to the presence of three iodine atoms in its structure, TIBEM-based polymers exhibit strong X-ray absorption. This property makes them ideal for use in contrast agents, allowing for clearer visualization of internal structures in medical imaging techniques like X-ray computed tomography (CT) scans.
* **Visualization of biological processes:** By incorporating TIBEM into polymers, researchers can track the movement and distribution of these polymers within biological systems. This capability allows for studying cell migration, tissue regeneration, and drug delivery pathways in real-time.

**2. Biomedical Applications:**

* **Drug delivery:** TIBEM-based polymers can serve as carriers for drugs, enabling targeted delivery to specific tissues or organs. Their high X-ray opacity allows for monitoring the delivery process and ensuring efficient drug distribution.
* **Biocompatible materials:** The polymer structure can be tailored to achieve biocompatibility, making them suitable for use in implants, tissue engineering scaffolds, and other medical devices.

**3. Other Applications:**

* **Microfluidics:** The X-ray opacity of TIBEM allows for the visualization of microfluidic devices, enabling precise control over fluid flow and the study of microfluidic systems.
* **Polymer chemistry:** The unique properties of TIBEM make it a valuable tool for understanding polymer structure, properties, and interactions.

**In summary:**

TIBEM is a versatile monomer that plays a significant role in advancing research across various fields. Its unique ability to impart high X-ray opacity to polymers opens doors for improving diagnostic imaging techniques, facilitating drug delivery, and developing new materials with diverse applications.

2-(2',3',5'-triiodobenzoyl)ethyl methacrylate: used for making biocompatible materials [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]