Compounds > 2-(2-(3-iodo-4-hydroxyphenyl)-6-benzimidazolyl)-6-(1-methyl-4-piperazyl)benzimidazole
Page last updated: 2024-12-07
2-(2-(3-iodo-4-hydroxyphenyl)-6-benzimidazolyl)-6-(1-methyl-4-piperazyl)benzimidazole
Description
The compound you're describing, 2-(2-(3-iodo-4-hydroxyphenyl)-6-benzimidazolyl)-6-(1-methyl-4-piperazyl)benzimidazole, is a complex organic molecule with several interesting features:
**Structure:**
* It contains two benzimidazole rings connected by a phenyl ring.
* One benzimidazole ring is substituted with a 1-methyl-4-piperazyl group.
* The other benzimidazole ring is substituted with a 3-iodo-4-hydroxyphenyl group.
**Potential Biological Activity:**
This molecule is a **synthetic derivative of a natural product** called **benzimidazole alkaloids**. Benzimidazole alkaloids are known to possess a wide range of biological activities, including:
* **Anti-cancer properties:** Some benzimidazoles have shown promise in treating various cancers due to their ability to inhibit cell growth and induce apoptosis (programmed cell death).
* **Anti-inflammatory activity:** Certain benzimidazoles can reduce inflammation by targeting inflammatory pathways.
* **Antimicrobial effects:** They can act against bacteria, fungi, and parasites.
* **Immunostimulatory effects:** Some benzimidazoles can enhance the immune response.
**Importance for Research:**
The specific compound you mentioned (2-(2-(3-iodo-4-hydroxyphenyl)-6-benzimidazolyl)-6-(1-methyl-4-piperazyl)benzimidazole) has not been extensively studied yet. However, its complex structure and potential biological activity make it an intriguing molecule for research. Researchers are interested in:
* **Understanding its mechanism of action:** How does this compound interact with biological targets to exert its effects?
* **Exploring its potential therapeutic applications:** Could this molecule be used to develop new drugs for various diseases?
* **Optimizing its properties:** Can researchers modify the structure of this compound to enhance its potency, selectivity, or bioavailability?
**Further Research:**
Before any potential therapeutic applications can be considered, further research is necessary to investigate the compound's safety, efficacy, and pharmacokinetic properties. This includes:
* **In vitro studies:** Evaluating the compound's activity in cell cultures.
* **In vivo studies:** Testing the compound in animal models.
* **Clinical trials:** Conducting human trials to assess the compound's safety and effectiveness.
Overall, 2-(2-(3-iodo-4-hydroxyphenyl)-6-benzimidazolyl)-6-(1-methyl-4-piperazyl)benzimidazole is a promising candidate for drug development research due to its potential biological activity and structural complexity. However, significant research is still required to fully understand its properties and explore its therapeutic potential.
2-(2-(3-iodo-4-hydroxyphenyl)-6-benzimidazolyl)-6-(1-methyl-4-piperazyl)benzimidazole: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
PubMed CID | 129169 |
SCHEMBL ID | 10070224 |
MeSH ID | M0176731 |
Synonyms (12)
Synonym |
iodohoechst 33258 |
HY-15630 |
CS-1318 |
106050-84-4 |
2-(2-(3-iodo-4-hydroxyphenyl)-6-benzimidazolyl)-6-(1-methyl-4-piperazyl)benzimidazole |
phenol, 2-iodo-4-(5-(4-methyl-1-piperazinyl)(2,5'-bi-1h-benzimidazol)-2'-yl)- |
SCHEMBL10070224 |
A906052 |
(e)-2-iodo-4-(6-(4-methylpiperazin-1-yl)-1',3'-dihydro-1h,2'h-[2,5'-bibenzo[d]imidazol]-2'-ylidene)cyclohexa-2,5-dien-1-one |
2-iodo-4-[6-[6-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]-1h-benzimidazol-2-yl]phenol |
AKOS040744080 |
PD118611 |
Research
Studies (4)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (50.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.56
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 12.56 (24.57) | Research Supply Index | 1.79 (2.92) | Research Growth Index | 4.36 (4.65) | Search Engine Demand Index | 0.00 (26.88) | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |