Page last updated: 2024-11-13
19,20-epoxycytochalasin q
Description
## 19,20-Epoxycytochalasin Q: A Powerful Tool for Actin Research
**19,20-Epoxycytochalasin Q** is a **potent inhibitor of actin polymerization** and a valuable research tool for studying the role of actin in various cellular processes.
**Here's a breakdown:**
* **Cytochalasins:** These are a family of fungal metabolites known to disrupt actin filament assembly and function.
* **19,20-Epoxycytochalasin Q:** This specific cytochalasin is a **highly effective inhibitor of actin polymerization**. It acts by binding to the barbed end of actin filaments, effectively blocking the addition of new actin monomers.
**Why is it important for research?**
1. **Understanding Actin Dynamics:** Actin is a ubiquitous protein essential for many cellular functions, including cell motility, division, and intracellular transport. 19,20-Epoxycytochalasin Q allows researchers to **study the effects of inhibiting actin polymerization** in various cell types and experimental systems. This provides valuable insights into the dynamic nature of actin filaments and their roles in cellular processes.
2. **Investigating Cellular Processes:** This inhibitor can be used to **disrupt specific actin-dependent processes** and explore their underlying mechanisms. This can help researchers understand how actin polymerization contributes to various cellular functions and how its disruption can lead to different diseases.
3. **Drug Development:** The potent inhibitory activity of 19,20-Epoxycytochalasin Q makes it a promising lead compound for **developing new drugs targeting actin polymerization** in diseases involving aberrant actin dynamics.
**In summary,** 19,20-Epoxycytochalasin Q is a valuable research tool with wide-ranging applications in cell biology and drug development. Its ability to effectively inhibit actin polymerization provides researchers with a powerful tool to dissect the intricate roles of actin in various cellular processes.
**Note:** This information is for general knowledge and educational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional for any health concerns.
19,20-epoxycytochalasin Q: from Xylaria sp.; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
Synonyms (3)
Synonym |
19,20-epoxycytochalasin q |
bdbm50242055 |
CHEMBL449278 , |
Protein Targets (1)
Inhibition Measurements
Biological Processes (20)
Molecular Functions (10)
Ceullar Components (5)
Research
Studies (5)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 3 (60.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.56
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 12.56 (24.57) | Research Supply Index | 1.79 (2.92) | Research Growth Index | 4.36 (4.65) | Search Engine Demand Index | 0.00 (26.88) | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |