15,16-dihydro-11-methylcyclopenta(a)phenanthren-17-one profile

15,16-Dihydro-11-methylcyclopenta(a)phenanthren-17-one is a synthetic compound that is not commonly known by this name. It is likely a chemical structure that needs further context to be fully understood.

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15,16-dihydro-11-methylcyclopenta(a)phenanthren-17-one: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	3034752
SCHEMBL ID	3346375
MeSH ID	M0047532

Synonym
ccris 972
15,16-dihydro-11-methyl-17h-cyclopenta(a)phenanthren-17-one
brn 2280058
15,16-dihydro-11-methylcyclopenta(a)phenanthren-17-one
17h-cyclopenta(a)phenanthren-17-one, 15,16-dihydro-11-methyl-
11-methyl-15,16-dihydro-17-oxocyclopenta(a)phenanthrene
11-methyl-15,16-dihydro-17h-cyclopenta(a)phenanthren-17-one
11-methyl-15,16-dihydrocyclopenta[a]phenanthren-17-one
unii-xf4wdu563x
11-ch3-cpp-17-one
11-methyl-15,16-dihydrocyclopenta(a)phenanthren-17-one
892-17-1
xf4wdu563x ,
SCHEMBL3346375
15,16-dihydro-11-methyl-17h-cyclopenta[a]phenanthren-17-one
DTXSID00237571
15,16-dihydro-11-methylcyclopenta[a]phenanthrene-17-one
cyclopenta(a)phenanthrene-11-methyl-15,16-dihydro-17-one
11-methyl-15h-cyclopenta(a)phenanthren-17(16h)-one
dihydro-11-methyl-17h-cyclopenta(a)phenanthren-17-one, 15,16-

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	11 (68.75)	18.7374
1990's	5 (31.25)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	17 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
croton oil [no description available]	1.96	1	N-acyl-hexosamine
benzo(a)pyrene Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.. benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.	1.96	1	ortho- and peri-fused polycyclic arene	carcinogenic agent; mouse metabolite
2-naphthylamine 2-Naphthylamine: A naphthalene derivative with carcinogenic action.. 2-naphthylamine : A naphthylamine carrying the amino group at position 2.	1.96	1	naphthylamine	carcinogenic agent
tetradecanoylphorbol acetate Tetradecanoylphorbol Acetate: A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA.. phorbol ester : Esters of phorbol, originally found in croton oil (from Croton tiglium, of the family Euphorbiaceae). A number of phorbol esters possess activity as tumour promoters and activate the mechanisms associated with cell growth. Some of these are used in experiments as activators of protein kinase C.. phorbol 13-acetate 12-myristate : A phorbol ester that is phorbol in which the hydroxy groups at the cyclopropane ring juction (position 13) and the adjacent carbon (position 12) have been converted into the corresponding acetate and myristate esters. It is a major active constituent of the seed oil of Croton tiglium. It has been used as a tumour promoting agent for skin carcinogenesis in rodents and is associated with increased cell proliferation of malignant cells. However its function is controversial since a decrease in cell proliferation has also been observed in several cancer cell types.	1.98	1	acetate ester; diester; phorbol ester; tertiary alpha-hydroxy ketone; tetradecanoate ester	antineoplastic agent; apoptosis inducer; carcinogenic agent; mitogen; plant metabolite; protein kinase C agonist; reactive oxygen species generator
15,16-dihydrocyclopenta(a)phenanthren-17-one 15,16-dihydrocyclopenta(a)phenanthren-17-one: structure	2.37	2
guanine [no description available]	1.96	1	2-aminopurines; oxopurine; purine nucleobase	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite

Condition	Relationship Strength	Studies
Aneuploid [description not available]	1.96	1
Experimental Neoplasms [description not available]	2.65	3
Cancer of Skin [description not available]	3.22	6
Cocarcinogenesis The combination of two or more different factors in the production of cancer.	2.36	2
Skin Neoplasms Tumors or cancer of the SKIN.	3.22	6
Breast Cancer [description not available]	1.98	1
Breast Neoplasms Tumors or cancer of the human BREAST.	1.98	1
Experimental Mammary Neoplasms [description not available]	1.95	1
Papilloma, Squamous Cell [description not available]	2.38	2
Papilloma A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)	2.38	2
Adenoma, Basal Cell [description not available]	1.97	1
Granulocytic Leukemia [description not available]	1.97	1
Cancer of Lung [description not available]	1.97	1
Adenoma A benign epithelial tumor with a glandular organization.	1.97	1
Leukemia, Myeloid Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.	1.97	1
Lung Neoplasms Tumors or cancer of the LUNG.	1.97	1
Mesothelioma A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)	1.97	1
Hepatocellular Carcinoma [description not available]	1.96	1
Cancer of Liver [description not available]	1.96	1
Carcinoma, Hepatocellular A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.	1.96	1
Liver Neoplasms Tumors or cancer of the LIVER.	1.96	1

15,16-dihydro-11-methylcyclopenta(a)phenanthren-17-one

Description

Cross-References

Synonyms (20)

Research

Studies (16)

Market Indicators

Research Demand Index: 11.46

Study Types