14-methylhexadecanoic acid profile

14-methylhexadecanoic acid, also known as **myristopalmitic acid**, is a branched-chain fatty acid.

Here's a breakdown:

* **Structure:** It has a 16-carbon chain with a methyl group (CH3) attached to the 14th carbon atom. The carboxylic acid group (-COOH) is located at the end of the chain.
* **Occurrence:** It's naturally found in small amounts in some animal fats and oils, including those from cows, sheep, and pigs.
* **Synthesis:** It can also be synthesized artificially.

**Why is it important for research?**

14-methylhexadecanoic acid has attracted attention in various research fields, including:

* **Biochemistry:** Its unique structure and presence in certain lipids make it interesting for studies on lipid metabolism, membrane fluidity, and the role of branched-chain fatty acids in biological processes.
* **Biomedical Research:** Research has suggested potential connections between 14-methylhexadecanoic acid and various health conditions. For example:
* **Cancer:** Studies have investigated its potential role in tumor growth and development.
* **Cardiovascular Disease:** Research has explored its influence on cholesterol levels and heart health.
* **Neurological Disorders:** Some studies have suggested a link to neurological function.
* **Food Chemistry:** Its presence in certain food sources has led to research on its potential impact on food quality and flavor.
* **Materials Science:** 14-methylhexadecanoic acid's chemical properties can be useful in developing new materials with specific characteristics.

**Ongoing Research:**

There is ongoing research to further understand the properties, roles, and potential applications of 14-methylhexadecanoic acid. This research will likely shed more light on its biological significance and potential applications in various fields.

It's crucial to note that research on 14-methylhexadecanoic acid is still relatively limited. Further studies are needed to fully understand its implications for human health and other areas of interest.

14-methylhexadecanoic acid: RN given refers to cpd without isomeric designation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

14-methylhexadecanoic acid : A methyl-branched fatty acid that is hexadecanoic acid (palmitic acid) substituted by a methyl group at position 14. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

ID Source	ID
PubMed CID	22207
CHEBI ID	84874
SCHEMBL ID	347119
MeSH ID	M0133838

Synonym
14-methylhexadecanoic acid
anteisoheptadecanoic acid
14-methyl-hexadecanoic acid
anteisomargaric acid
(+)-14-methyl palmitic acid
LMFA01020011
14-methylpalmitic acid
CHEBI:84874
hexadecanoic acid, 14-methyl-
5918-29-6
SCHEMBL347119
FXUKWLSZZHVEJD-UHFFFAOYSA-N
Q27158141
[1,3,5]triazine-2,4,6-trithiol
DTXSID60974612
CS-0083720
PD078020
HY-121940

Role	Description
plant metabolite	Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
mammalian metabolite	Any animal metabolite produced during a metabolic reaction in mammals.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
methyl-branched fatty acid	Any branched-chain fatty acid containing methyl branches only.
branched-chain saturated fatty acid	Any saturated fatty acid with a carbon side-chain or isopropyl termination.
long-chain fatty acid	A fatty acid with a chain length ranging from C13 to C22.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	6 (50.00)	18.7374
1990's	1 (8.33)	18.2507
2000's	3 (25.00)	29.6817
2010's	1 (8.33)	24.3611
2020's	1 (8.33)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	12 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
palmitic acid Palmitic Acid: A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.. hexadecanoic acid : A straight-chain, sixteen-carbon, saturated long-chain fatty acid.	2.33	2	long-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; Daphnia magna metabolite; EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor; plant metabolite
urea pseudourea: clinical use; structure. isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.	2.03	1	isourea; monocarboxylic acid amide; one-carbon compound	Daphnia magna metabolite; Escherichia coli metabolite; fertilizer; flour treatment agent; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
1-anilino-8-naphthalenesulfonate 1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd. 8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.	2.02	1	aminonaphthalene; naphthalenesulfonic acid	fluorescent probe
2-methylbutanoic acid 2-methylbutanoic acid: RN given refers to parent cpd without isomeric designation. 2-methylbutyric acid : A methylbutyric acid comprising a butyric acid core carrying a 2-methyl substituent. Produced from amino acid leucine during nutrient starvation in bacteria.	1.97	1	methylbutyric acid	bacterial metabolite; human metabolite
aseanostatin p5 aseanostatin P5: from actinomycetes; inhibits myeloperoxidase release from human polymorphonuclear leukocytes; structure given in first source; RN given refers to cpd without isomeric designation. 12-methyltetradecanoic acid : A branched-chain saturated fatty acid comprising tetradecanoic acid carrying a 12-methyl substituent.	2.67	3	branched-chain saturated fatty acid; long-chain fatty acid
silver Silver: An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.	2.03	1	copper group element atom; elemental silver	Escherichia coli metabolite
4-pentenoic acid 4-pentenoic acid: inhibitor of fatty acid oxidation; RN given refers to parent cpd. pent-4-enoic acid : A pentenoic acid having the double bond at position 4.	2.02	1	pentenoic acid
carcinolipin carcinolipin: structure	1.96	1
betadex beta-Cyclodextrins: Cyclic GLUCANS consisting of seven (7) glucopyranose units linked by 1,4-glycosidic bonds.	2.03	1	cyclodextrin
dimyristoylphosphatidylcholine 1,2-di-O-myristoyl-sn-glycero-3-phosphocholine : A 1,2-diacyl-sn-glycero-3-phosphocholine where the two phosphatidyl acyl groups are specified as tetradecanoyl (myristoyl).. dimyristoyl phosphatidylcholine : A phosphatidylcholine where the phosphatidyl acyl groups are specified as tetradecanoyl (myristoyl).	2.04	1	1,2-diacyl-sn-glycero-3-phosphocholine; phosphatidylcholine 28:0; tetradecanoate ester	antigen; mouse metabolite
heptakis(2,6-o-dimethyl)beta-cyclodextrin heptakis(2,6-O-dimethyl)beta-cyclodextrin: stimulant for Bordetella pertussis Phase I	2.03	1
glucagon Glucagon: A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511). glucagon : A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence.	2.1	1	peptide hormone
glycolipids [no description available]	2.02	1
leptin Leptin: A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.	2.1	1

Condition	Relationship Strength	Studies
Liver Steatosis [description not available]	2.1	1
Fatty Liver Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.	2.1	1
Carcinoma 256, Walker A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed)	1.96	1

14-methylhexadecanoic acid

Description

Cross-References

Synonyms (18)

Roles (2)

Drug Classes (3)

Research

Studies (12)

Market Indicators

Research Demand Index: 19.89

Study Types