Page last updated: 2024-12-08

13-methyltetradecanoic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

13-methyltetradecanoic acid, also known as **myristopalmitic acid**, is a branched-chain fatty acid. It's a relatively uncommon fatty acid found in various sources, including:

* **Animal fats:** Particularly in milk fat, but also found in other animal products.
* **Some plants:** Notably, in certain palm oils.

**Importance in Research:**

While it's not as widely studied as other fatty acids, 13-methyltetradecanoic acid has garnered interest in research due to its potential role in:

* **Inflammatory responses:** Some studies suggest it might have anti-inflammatory properties, potentially beneficial for conditions like rheumatoid arthritis or inflammatory bowel disease.
* **Lipid metabolism:** Its unusual structure might affect how it's processed by the body compared to other fatty acids, influencing lipid metabolism and potentially impacting cardiovascular health.
* **Antimicrobial activity:** Some research suggests it might possess antimicrobial activity against certain bacteria.
* **Biomarker potential:** Its presence in certain tissues or fluids might serve as a biomarker for specific conditions or metabolic states.

**Key Research Directions:**

Current research focuses on understanding:

* **Its biological mechanisms:** How it interacts with cellular processes and pathways.
* **Its health implications:** Potential benefits and risks associated with its presence in the diet or its metabolism.
* **Its potential applications:** Exploring its use in pharmaceuticals, supplements, or other applications.

**Limitations:**

Despite the interest, research on 13-methyltetradecanoic acid is still in its early stages. More research is needed to fully understand its properties, mechanisms, and potential applications.

**Overall, 13-methyltetradecanoic acid is a relatively uncommon fatty acid with potential implications for health and research. While more studies are needed to fully elucidate its role and significance, its unique structure and potential benefits make it a promising area of investigation.**

isopentadecanoic acid : A branched-chain saturated fatty acid comprising tetradecanoic (myristic) acid substituted at position 13 by a methyl group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID151014
CHEMBL ID495851
CHEBI ID39250
SCHEMBL ID366393
MeSH IDM0088939

Synonyms (37)

Synonym
13-methylmyristic acid, >=98% (capillary gc)
i-15:0
13-methyl tetradecanoic acid
CHEBI:39250 ,
13-methyltetradecanoic acid
2485-71-4
iso-c15
13-methyl-tetradecansaeure
iso-c15:0
13-mtd
i-c15:0
15:0 iso
13-methylmyristic acid
isopentadecanoic acid
subtilopentadecanoic acid
isopentadecylic acid
LMFA01020009
13-methyl-tetradecanoic acid
CHEMBL495851
tetradecanoic acid, 13-methyl-
unii-m09t9m1lty
m09t9m1lty ,
13-methylmyristate
iso-pentadecanoic acid
SCHEMBL366393
13-methyltetradecanoicacid
DTXSID90179552
J-015704
FT-0714166
Q20179071
ledsf3
A928069
MS-23435
HY-131503
CS-0136053
PD078182
AKOS040748729

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" The ID50 dosage of 13-MTD for these tumor cells ranged from 10 to 25 microg/ml."( Induction of apoptotic cell death and in vivo growth inhibition of human cancer cells by a saturated branched-chain fatty acid, 13-methyltetradecanoic acid.
Chen, H; Chen, X; Huang, M; Liu, S; Yang, Z; Zheng, J, 2000
)
0.51
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (3)

ClassDescription
long-chain fatty acidA fatty acid with a chain length ranging from C13 to C22.
branched-chain saturated fatty acidAny saturated fatty acid with a carbon side-chain or isopropyl termination.
methyl-branched fatty acidAny branched-chain fatty acid containing methyl branches only.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID380058Antimicrobial activity against Streptococcus mutans MT5092000Journal of natural products, May, Volume: 63, Issue:5
Identification and total synthesis of a novel dimethylated fatty acid from the Caribbean sponge Calyx podatypa.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (19)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (26.32)18.7374
1990's3 (15.79)18.2507
2000's8 (42.11)29.6817
2010's3 (15.79)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 19.00

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index19.00 (24.57)
Research Supply Index3.04 (2.92)
Research Growth Index4.41 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (19.00)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other20 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]