13-acetoxysarcocrassolide: cytotoxic, from Sarcophyton crassocaule; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Sarcophyton | genus | [no description available] | Orchidaceae | A plant family of the order Asparagales. All members of the orchid family have the same bilaterally symmetrical flower structure, with three sepals, but the flowers vary greatly in color and shape.[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 21775908 |
| CHEMBL ID | 485787 |
| MeSH ID | M0574755 |
| Synonym |
|---|
| 13-acetoxysarcocrassolide |
| CHEMBL485787 |
| [(1s,3s,5s,8e,12e,14s,15s)-5,9,13-trimethyl-18-methylidene-17-oxo-4,16-dioxatricyclo[13.3.0.03,5]octadeca-8,12-dien-14-yl] acetate |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID378590 | Cytotoxicity against mouse P388 cells | 2000 | Journal of natural products, Dec, Volume: 63, Issue:12 | Cytotoxic cembrenolides and steroids from the formosan soft coral Sarcophyton crassocaule. |
| AID461536 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated iNOS protein expression by measuring iNOS protein level at 10 uM by Western blot relative to untreated control | 2010 | Bioorganic & medicinal chemistry, Mar-01, Volume: 18, Issue:5 | Cytotoxic and anti-inflammatory cembranoids from the Dongsha Atoll soft coral Sarcophyton crassocaule. |
| AID378589 | Cytotoxicity against human KB cells | 2000 | Journal of natural products, Dec, Volume: 63, Issue:12 | Cytotoxic cembrenolides and steroids from the formosan soft coral Sarcophyton crassocaule. |
| AID378588 | Cytotoxicity against human HT29 cells | 2000 | Journal of natural products, Dec, Volume: 63, Issue:12 | Cytotoxic cembrenolides and steroids from the formosan soft coral Sarcophyton crassocaule. |
| AID378587 | Cytotoxicity against human A549 cells | 2000 | Journal of natural products, Dec, Volume: 63, Issue:12 | Cytotoxic cembrenolides and steroids from the formosan soft coral Sarcophyton crassocaule. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.98) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||