11-mercaptoundecanol profile

**11-Mercaptoundecanol** is a long-chain fatty alcohol with a thiol group (sulfhydryl group, -SH) at the end of the molecule.

**Chemical Structure:**

CH3(CH2)10CH2SH

**Properties:**

* **Appearance:** Colorless to light yellow liquid
* **Odor:** Strong, pungent odor
* **Solubility:** Insoluble in water, soluble in organic solvents
* **Boiling Point:** 190-195 °C (374-383 °F) at 15 mmHg

**Importance in Research:**

11-Mercaptoundecanol is used in research for various purposes, including:

* **Biomedical Research:**
* **Cell Signaling:** It is a potential signaling molecule involved in cell communication and regulation.
* **Drug Delivery:** Its thiol group can be used to attach drugs or other molecules for targeted delivery.
* **Antioxidant Activity:** Its thiol group can act as a reducing agent and protect cells from oxidative damage.

* **Materials Science:**
* **Self-Assembled Monolayers (SAMs):** Its thiol group allows it to form self-assembled monolayers on gold surfaces, creating a protective coating.
* **Polymer Synthesis:** It can be used as a building block for the synthesis of polymers with specific properties.

* **Analytical Chemistry:**
* **Chromatographic Analysis:** It can be used as a stationary phase in gas chromatography for the separation of volatile compounds.

**Specific Applications:**

* **Cancer Research:** Studies have shown that 11-mercaptoundecanol can inhibit the growth of cancer cells.
* **Neurodegenerative Diseases:** It is being investigated as a potential therapeutic agent for Alzheimer's disease and Parkinson's disease.
* **Biomaterial Development:** Its thiol group makes it suitable for modifying biomaterials, such as hydrogels and nanoparticles.

**Note:** 11-Mercaptoundecanol is a relatively new research chemical, and its full potential in various fields is still under investigation.

**Disclaimer:** The information provided is for general knowledge and informational purposes only, and does not constitute medical advice. Consult a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.

11-mercaptoundecanol: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	261824
SCHEMBL ID	343853
MeSH ID	M0511573

Synonym
nsc94792
73768-94-2
nsc-94792
11-mercapto-1-undecanol, 97%
NCIOPEN2_006068
11-mercaptoundecanol
11-sulfanylundecan-1-ol
undecane-1,11-dithiol;11-mercaptoundecan-1-ol
A837916
11-mercapto-1-undecanol
AKOS015913280
11-hydroxyundecanethiol
11-mercaptoundecan-1-ol
SCHEMBL343853
11-sulfanyl-1-undecanol #
1-undecanol, 11-mercapto-
11-mercapto-1-undecanol, 99%
DTXSID30294152
c11h24os
DS-11407
mfcd00239433
AMY37881
C76355
YCA76894
11-mercapto-1-undecanethiol

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (31.25)	29.6817
2010's	10 (62.50)	24.3611
2020's	1 (6.25)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	16 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
ethylene glycol Ethylene Glycol: A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.. ethanediol : Any diol that is ethane or substituted ethane carrying two hydroxy groups.. ethylene glycol : A 1,2-glycol compound produced via reaction of ethylene oxide with water.	2.47	2	ethanediol; glycol	metabolite; mouse metabolite; solvent; toxin
sulfites Sulfites: Inorganic salts of sulfurous acid.. sulfites : Any sulfurous acid derivative that is a salt or an ester of sulfurous acid.. organosulfonate oxoanion : An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid.. sulfite : A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H2SO3).	2.05	1	divalent inorganic anion; sulfur oxide; sulfur oxoanion
tyrosine Tyrosine: A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.. tyrosine : An alpha-amino acid that is phenylalanine bearing a hydroxy substituent at position 4 on the phenyl ring.	2.06	1	amino acid zwitterion; erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid; proteinogenic amino acid; tyrosine	EC 1.3.1.43 (arogenate dehydrogenase) inhibitor; fundamental metabolite; micronutrient; nutraceutical
histidine Histidine: An essential amino acid that is required for the production of HISTAMINE.. L-histidine : The L-enantiomer of the amino acid histidine.. histidine : An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3.	2.02	1	amino acid zwitterion; histidine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite
3-mercaptopropionic acid 3-Mercaptopropionic Acid: An inhibitor of glutamate decarboxylase. It decreases the GAMMA-AMINOBUTYRIC ACID concentration in the brain, thereby causing convulsions.. 3-mercaptopropanoic acid : A mercaptopropanoic acid that is propanoic acid carrying a sulfanyl group at position 3.	2.21	1	mercaptopropanoic acid	algal metabolite
dodecylmercaptan dodecylmercaptan: used in polymerization of neoprenes; structure	2.06	1
silver Silver: An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.	2.51	2	copper group element atom; elemental silver	Escherichia coli metabolite
gold Gold: A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.	3.58	8	copper group element atom; elemental gold
tirofiban Tirofiban: Tyrosine analog and PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX antagonist that inhibits PLATELET AGGREGATION and is used in the treatment of ACUTE CORONARY SYNDROME.. tirofiban : A member of the class of piperidines that is L-tyrosine in which a hydrogen attached to the amino group is replaced by a butylsulfonyl group and in which the hydrogen attached to the phenolic hydroxy group is replaced by a 4-(piperidin-4-yl)butyl group.	2.06	1	L-tyrosine derivative; piperidines; sulfonamide	anticoagulant; fibrin modulating drug; platelet glycoprotein-IIb/IIIa receptor antagonist
fibrinogen Fibrinogen: Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.. D-iditol : The D-enantiomer of iditol.	2.06	1	iditol	fungal metabolite
11-mercaptoundecanoic acid [no description available]	3.15	5
laccase Laccase: A copper-containing oxidoreductase enzyme that catalyzes the oxidation of 4-benzenediol to 4-benzosemiquinone. It also has activity towards a variety of O-quinols and P-quinols. It primarily found in FUNGI and is involved in LIGNIN degradation, pigment biosynthesis and detoxification of lignin-derived products.	2.15	1
16-mercaptohexadecanoic acid [no description available]	2.15	1
cytochrome c-t Cytochromes c: Cytochromes of the c type that are found in eukaryotic MITOCHONDRIA. They serve as redox intermediates that accept electrons from MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III and transfer them to MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV.	2.45	2
oligonucleotides [no description available]	2.05	1

Condition	Indicated	Relationship Strength	Studies	Trials
Electrolytes Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)	0	2.03	1	0

11-mercaptoundecanol

Description

Cross-References

Synonyms (25)

Research

Studies (16)

Market Indicators

Research Demand Index: 21.64

Study Types