Page last updated: 2024-12-05

11-aminoundecanoic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

11-Aminoundecanoic acid, also known as ω-aminoundecanoic acid, is a long-chain amino acid with a variety of potential applications. It is a key building block in the synthesis of nylon-11, a high-performance polymer known for its excellent toughness, flexibility, and resistance to chemicals and abrasion. 11-Aminoundecanoic acid can be synthesized through different methods, including the hydroformylation of undecylenic acid, the hydrogenation of 11-cyanoundecanoic acid, and the ring-opening polymerization of ε-caprolactam followed by hydrolysis. It is also a precursor to other valuable chemicals, such as undecylenic acid and 11-amino-1-undecanol, which find uses in pharmaceuticals, cosmetics, and lubricants. 11-Aminoundecanoic acid is an important intermediate in the production of various polymers and has been studied for its potential applications in biomaterials, drug delivery, and biocompatible coatings. Research is ongoing to explore its potential in these areas, as its unique properties make it an attractive candidate for various technological advancements.'

11-aminoundecanoic acid: N1 is same as NM; first source discusses ammonium salt of the cpd; RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID17083
CHEMBL ID1903820
CHEBI ID82387
SCHEMBL ID35890
MeSH IDM0081477

Synonyms (60)

Synonym
nsc-240503
undecanoic acid, 11-amino-
nsc240503
nsc-662428
nsc 662428
nsc 240503
brn 1767291
nci-c50613
hsdb 4349
11-aminoundecylic acid
ccris 39
einecs 219-417-6
11-aminoundecanoic acid
2432-99-7
nsc662428
LMFA01100004
11-amino-undecanoic acid
11-aminoundecanoic acid, 97%
NCGC00163971-01
25587-80-8
omega-aminoundecylic acid;aminoundecanoicacid
A22758
rilsan t
25035-04-5
rilsan w 1482
reilsan es natural
C19325
ec 219-417-6
unii-sfu34976hb
4-04-00-02823 (beilstein handbook reference)
sfu34976hb ,
FT-0634271
AKOS015855192
11-aminoundecanoic acid [hsdb]
aminoundecanoic acid, 11-
11-aminoundecanoic acid [iarc]
AM82457
SCHEMBL35890
CHEBI:82387 ,
W-107330
CHEMBL1903820
11-aminoundecanoicacid
.omega.-aminoundecanoic acid
DTXSID5020077
mfcd00008150
11-aminoundecanoic acid, purum, >=97.0% (nt)
F0001-0827
CS-W015547
2-methylthio-4,6-pyrimideniol
F14580
AS-16035
Q15632699
h-aund(11)-oh
EN300-116808
HY-W014831
aminoundecanoic acid; nsc 240503; nsc 662428; undecanoic acid, 11-amino-;
11-aminoundecanoic acid 100 microg/ml in acetonitrile:methanol
PD124920
SY012650
BP-28235
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
medium-chain fatty acidAny fatty acid with a chain length of between C6 and C12.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (5)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency0.01120.000214.376460.0339AID588532
retinoid X nuclear receptor alphaHomo sapiens (human)Potency25.11890.000817.505159.3239AID588546
pregnane X nuclear receptorHomo sapiens (human)Potency44.66840.005428.02631,258.9301AID720659
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency0.00280.010039.53711,122.0200AID588545
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency1.53550.000627.21521,122.0200AID720636
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (36.36)18.7374
1990's1 (9.09)18.2507
2000's3 (27.27)29.6817
2010's2 (18.18)24.3611
2020's1 (9.09)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 34.95

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index34.95 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index4.66 (4.65)
Search Engine Demand Index43.27 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (34.95)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other12 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]